New mathematical and statistical methods that inform the control of infectious disease outbreaks. Emerging infectious diseases are an ever-present threat to our community, as highlighted by the recent SARS epidemic and current fears concerning avian influenza. The research proposed by this project will help policy makers implement effective border control and outbreak control against a variety of emerging and re-emerging infectious diseases, including SARS, influenza and the deliberate release o ....New mathematical and statistical methods that inform the control of infectious disease outbreaks. Emerging infectious diseases are an ever-present threat to our community, as highlighted by the recent SARS epidemic and current fears concerning avian influenza. The research proposed by this project will help policy makers implement effective border control and outbreak control against a variety of emerging and re-emerging infectious diseases, including SARS, influenza and the deliberate release of an infectious disease such as smallpox. The project will enhance preparedness through a better understanding of the relative merits of different control strategies, and provide new methodology that can dynamically guide border and outbreak control in the midst of an outbreak by making effective use of data. Read moreRead less
Can an anti-HIV gene in blood stem cells protect from immune depletion by HIV? Approximately 15,000 individuals in Australia are currently HIV infected. Gene therapy has the capacity to remove antiretroviral treatment related issues, dramatically decrease treatment costs and simplify treatment of HIV.
In this study we will model a new approach to treat HIV in which the patient's own cells are used as the therapy by incorporating an anti-HIV gene. These cells are then re-introduced into the p ....Can an anti-HIV gene in blood stem cells protect from immune depletion by HIV? Approximately 15,000 individuals in Australia are currently HIV infected. Gene therapy has the capacity to remove antiretroviral treatment related issues, dramatically decrease treatment costs and simplify treatment of HIV.
In this study we will model a new approach to treat HIV in which the patient's own cells are used as the therapy by incorporating an anti-HIV gene. These cells are then re-introduced into the patient.
The strong mathematical focus of this project, and its application to a promising approach against HIV, will place Australia at the forefront of the mathematics of gene research and contribute to the National Priority Area of Promoting and Maintaining Good Health and the Priority Goal of Preventative Healthcare.
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Complexity-manageable methodologies and efficient computational tools for analysis and design of large-scale systems. The tools to be developed in this project have impact on a broad range of disciplines, including system analysis, feedback control technology, signal processing, communication network, and information theory. Practically, the success of this project will create cutting edge technologies applicable to design and management of important infrastructures of the modern society such as ....Complexity-manageable methodologies and efficient computational tools for analysis and design of large-scale systems. The tools to be developed in this project have impact on a broad range of disciplines, including system analysis, feedback control technology, signal processing, communication network, and information theory. Practically, the success of this project will create cutting edge technologies applicable to design and management of important infrastructures of the modern society such as communication networks, transportation systems, electrical power grids, and collaborative intelligent machines, and water distribution networks. Success of this project will bring novel methodologies and computational tools which help engineers to systematically design and validate the performance of their engineering systems.Read moreRead less
Robustness Analysis and Control Design of Distributed and Networked Systems. The theory and computational tools to be developed in this project have impact on a broad range of areas, including various engineering disciplines, biology, and medical and environmental sciences. In terms of practical interests, this project will create cutting edge technologies which are applicable to important infrastructures of the modern society such as communication networks, transportation systems, electrical po ....Robustness Analysis and Control Design of Distributed and Networked Systems. The theory and computational tools to be developed in this project have impact on a broad range of areas, including various engineering disciplines, biology, and medical and environmental sciences. In terms of practical interests, this project will create cutting edge technologies which are applicable to important infrastructures of the modern society such as communication networks, transportation systems, electrical power grids, collaborative intelligent machines, and water distribution networks. Read moreRead less
Enhancing Performance in Controlling Finite Level Quantum Systems with Uncertainties. Australia is a recognized leader in the international race to develop quantum frontier technologies. Funding of this project will consolidate and strengthen Australia's leadership in quantum information technology by developing new theory and tractable control approaches to deal with typical uncertainties arising in practical applications and to enhance performance in controlling finite level quantum systems, a ....Enhancing Performance in Controlling Finite Level Quantum Systems with Uncertainties. Australia is a recognized leader in the international race to develop quantum frontier technologies. Funding of this project will consolidate and strengthen Australia's leadership in quantum information technology by developing new theory and tractable control approaches to deal with typical uncertainties arising in practical applications and to enhance performance in controlling finite level quantum systems, and will also enhance the capability of Australian researchers to participate in promising quantum technologies. The outcomes of this project will play an important role in establishing Australian quantum information industries, which can provide new commercial opportunities and benefit Australia's economy.Read moreRead less
Robust and Distributed Control of Quantum Systems. Australia has considerable strengths in quantum technology research. As these technologies advance, the issue of control and in particular feedback control becomes a critical one. This research project will strengthen Australia's position in quantum technology by developing new methodologies for designing high performance robust and distributed feedback controllers for quantum systems. The project will also add to Australia's strength in quantum ....Robust and Distributed Control of Quantum Systems. Australia has considerable strengths in quantum technology research. As these technologies advance, the issue of control and in particular feedback control becomes a critical one. This research project will strengthen Australia's position in quantum technology by developing new methodologies for designing high performance robust and distributed feedback controllers for quantum systems. The project will also add to Australia's strength in quantum technology by contributing to the research training of young researchers with expertise both in control systems engineering and quantum technology. This project will help Australia reap the maximum possible benefit from the new industries to emerge from the field of quantum technology.Read moreRead less
Robust Feedback Control in Quantum Technology. Australia has considerable strengths in quantum technology research. As these technologies advance, the issue of control and in particular feedback control becomes a critical one. This research project will strengthen Australia's position in quantum technology by developing new methodologies for designing high performance robust feedback controllers for quantum systems. The project will also add to Australia's strength in quantum technology by contr ....Robust Feedback Control in Quantum Technology. Australia has considerable strengths in quantum technology research. As these technologies advance, the issue of control and in particular feedback control becomes a critical one. This research project will strengthen Australia's position in quantum technology by developing new methodologies for designing high performance robust feedback controllers for quantum systems. The project will also add to Australia's strength in quantum technology by contributing to the research training of young researchers with expertise both in control systems engineering and quantum technology. This project will help Australia reap the maximum possible benefit from the new industries to emerge from the field of quantum technology.
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Uncertain Systems Theory applied to Nonlinear Robust Control and Filtering. Feedback control systems are becoming increasingly important in manufacturing industry, the automotive industry, defence applications as well as in many non-industrial applications such as the management of the environment or the economy. By developing new techniques for the design of high performance robust nonlinear controllers and filters which are widely applicable in industrial applications, this project will help m ....Uncertain Systems Theory applied to Nonlinear Robust Control and Filtering. Feedback control systems are becoming increasingly important in manufacturing industry, the automotive industry, defence applications as well as in many non-industrial applications such as the management of the environment or the economy. By developing new techniques for the design of high performance robust nonlinear controllers and filters which are widely applicable in industrial applications, this project will help make existing industrial technologies more efficient and make new industrial technologies feasible. Moreover, the research training carried out in the project will add to available a pool of experts in the areas of robust nonlinear control and filtering. Read moreRead less
New quantum and robust control theory with applications to quantum optics. The application of quantum mechanics to the creation of quantum technology promises to be one of the most exciting technological developments of this century. Possible applications of quantum technologies include vastly improved sensors to search for minerals or gravity waves, secure quantum cryptography, and quantum computing. Quantum feedback control is a key tool in quantum technology. This project will lay the fou ....New quantum and robust control theory with applications to quantum optics. The application of quantum mechanics to the creation of quantum technology promises to be one of the most exciting technological developments of this century. Possible applications of quantum technologies include vastly improved sensors to search for minerals or gravity waves, secure quantum cryptography, and quantum computing. Quantum feedback control is a key tool in quantum technology. This project will lay the foundations of systematic theories of robust, coherent and nonlinear quantum feedback control and lead to advances in the control of highly resonant systems which underlie experimental quantum and nano technology. This will enable Australia to reap great benefits as this new technological area emerges.Read moreRead less
Robust Dynamical System Identification. Innovative robust system identification methods are a Frontier Technology for Transforming Australian Industries. Robust system identification will provide a technology for generating high fidelity models by the use of breakthrough science. With the majority of advanced industrial control systems reliant on accurate models significant savings could be made due to the implicit improvement in process control. Furthermore, system identification is a key enabl ....Robust Dynamical System Identification. Innovative robust system identification methods are a Frontier Technology for Transforming Australian Industries. Robust system identification will provide a technology for generating high fidelity models by the use of breakthrough science. With the majority of advanced industrial control systems reliant on accurate models significant savings could be made due to the implicit improvement in process control. Furthermore, system identification is a key enabling technology in most modern systems (e.g. in aerospace, manufacturing, mining, minerals processing and telecommunications) and is also important in the emerging areas of nanotechnology and systems biology.Read moreRead less