Human Malarial Immunity And Risk Of Malaria Post-partum And During Infancy
Funder
National Health and Medical Research Council
Funding Amount
$263,079.00
Summary
Malaria is a major cause of morbidity and mortality worldwide, particularly in children and pregnant women. This project aims to understand and identify immune responses that protect pregnant women and infants from malaria. This knowledge is critical to understanding immunity to malaria in high risk groups and for the development and use of vaccines to protect pregnant women and their babies.
A Safety, Tolerability, Pharmacokinetic And Efficacy Study Of Azithromycin Plus Piperaquine As Intermittent Presumptive Treatment In Pregnant Papua New Guinean Women
Funder
National Health and Medical Research Council
Funding Amount
$345,684.00
Summary
The purpose of this research is to investigate a new antimalarial combination therapy, azithromycin (AZI) plus piperaquine (PQ), for the prevention of malaria infection in pregnant Papua New Guinean women. It is anticipated that these studies will provide sufficient data to determine if AZI-PQ is a suitable alternative treatment option in PNG, and other countries which have similar malaria epidemiology including the presence of drug resistant parasites.