Immuno-epidemiological insights into the development of immunity to malaria and drug resistance. This project aims to better understand the maintenance and acquisition of immunity to malaria in high risk groups. It will also attempt to elucidate how immunity can interfere with the therapeutic efficacy of antimalarials, especially in the assessment of emerging drug resistance. The over-riding hypothesis is that differences in malaria transmission will lead to differential acquisition of immunity ....Immuno-epidemiological insights into the development of immunity to malaria and drug resistance. This project aims to better understand the maintenance and acquisition of immunity to malaria in high risk groups. It will also attempt to elucidate how immunity can interfere with the therapeutic efficacy of antimalarials, especially in the assessment of emerging drug resistance. The over-riding hypothesis is that differences in malaria transmission will lead to differential acquisition of immunity and efficacy of malaria interventions within and between populations. Understanding immunity to malaria is pivotal to develop new interventions, to understand the effectiveness of current malaria treatment and control programs to reduce the global burden of malarial disease.Read moreRead less
Evaluation of the potential of colostrum-derived anti-influenza antibody for the treatment and prevention of influenza. The project addresses a common disease problem, influenza, with a novel application of antibody technology. The technology may safely provide protection and cost effective treatment for those members of the community who are least protected by current approaches. The product can be cost-effective and readily available to enable the public to self medicate in high risk situation ....Evaluation of the potential of colostrum-derived anti-influenza antibody for the treatment and prevention of influenza. The project addresses a common disease problem, influenza, with a novel application of antibody technology. The technology may safely provide protection and cost effective treatment for those members of the community who are least protected by current approaches. The product can be cost-effective and readily available to enable the public to self medicate in high risk situations, or to be used as a public health tool in situtions to control outbreaks in those most susceptible to serious disease. The production system that enabled the creation of the technology is the advanced Australian dairy industry. Farmers with herds participating will receive a significant income benefit from, what was before, largely a waste product.Read moreRead less