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Imaging the invisible. This project aims to develop imaging technology to see and quantify objects normally invisible with X-rays. It will develop an X-ray imaging system that should provide orders of magnitude greater sensitivity to subtle changes in material composition than conventional radiography. It will devise quantitative image analysis tools for isolating specific materials of interest from complex multi-material samples, including low density components that often go undetected. Indust ....Imaging the invisible. This project aims to develop imaging technology to see and quantify objects normally invisible with X-rays. It will develop an X-ray imaging system that should provide orders of magnitude greater sensitivity to subtle changes in material composition than conventional radiography. It will devise quantitative image analysis tools for isolating specific materials of interest from complex multi-material samples, including low density components that often go undetected. Industries that could benefit significantly from this technology include airport security, the mining sector, agriculture, manufacturing quality control, and biomedical researchers studying anatomical form and function.Read moreRead less
Non-destructing X-ray testing. This project aims to improve imaging with X-rays, providing better image quality with higher throughput at a lower radiation dose. It will develop an X-ray imaging system that provides orders of magnitude greater sensitivity for detecting low-density objects that are often invisible with conventional X-ray scanners, and quantitative image analysis tools that can isolate materials from complex multi-material samples and detect individual chemical elements. Significa ....Non-destructing X-ray testing. This project aims to improve imaging with X-rays, providing better image quality with higher throughput at a lower radiation dose. It will develop an X-ray imaging system that provides orders of magnitude greater sensitivity for detecting low-density objects that are often invisible with conventional X-ray scanners, and quantitative image analysis tools that can isolate materials from complex multi-material samples and detect individual chemical elements. Significant benefits from these technologies are expected in industries including airport security, mining, agriculture, manufacturing quality control, and in research fields from medicine to geology.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101222
Funder
Australian Research Council
Funding Amount
$371,392.00
Summary
The development of novel magnetic resonance imaging methods to investigate brain structure and function. Magnetic resonance imaging (MRI) is a non-invasive method that has revolutionised neuroscience. The goal of this project is to develop state-of-the-art MRI analysis methods that reveal new information about brain structure and function. These novel neuroimaging tools will be instrumental in furthering our understanding of how the brain works.
Advanced magnetic resonance imaging methods for the characterisation of brain structure and function. Magnetic resonance imaging (MRI) is a non-invasive method that has revolutionised the development of neuroscience and neurology. The goal of this project is to develop advanced MRI methods for the study of brain structure and function which will be applied to the investigation of epilepsy and stroke.
How the red blood cell loses its nucleus. This project aims to provide insights into erythroid enucleation, the process by which red blood cells extrude their nucleus so that they can circulate through the microvasculature. Although the enucleated character of mammalian red blood cells has been known for more than 150 years, the mechanism underlying this process is virtually unknown. This project will use a live imaging approach to characterise in vivo the cellular interactions and molecular pat ....How the red blood cell loses its nucleus. This project aims to provide insights into erythroid enucleation, the process by which red blood cells extrude their nucleus so that they can circulate through the microvasculature. Although the enucleated character of mammalian red blood cells has been known for more than 150 years, the mechanism underlying this process is virtually unknown. This project will use a live imaging approach to characterise in vivo the cellular interactions and molecular pathways required for enucleation. The project will provide a molecular and cellular road map of enucleation that may be utilised to enhance the bulk therapeutic in vitro production of red blood cells for veterinary and human purposes.Read moreRead less
Haemodynamic investigation of flow diverter stents for the treatment of intracranial aneurysms. This project will explore the engineering of a flow diverter, an endovascular device for the treatment of brain aneurysms. The project will determine the optimal design of new types of flow diverters, which in turn could improve the effectiveness of treatments, thus reducing the associated costs of cerebral haemorrhage and stroke.
In-vivo detection of airway injury and disease using phase contrast X-ray velocimetry. Currently diagnosis of lung disease, a major cause of death in humans, is based on clinical symptoms that do not usually manifest until the disease is well advanced. This project will develop a novel imaging technique, X-ray velocimetry, to detect changes in tissue before symptoms arise, potentially leading to strategies for managing lung diseases.
Low dose methods for detecting early lung disease using x-ray phase contrast imaging. This project will develop a highly sensitive, low-dose x-ray imaging technique for the early detection of diseases of the respiratory system. This technology will have the potential to be used as a diagnostic screening tool to reduce the incidence of respiratory related deaths from diseases such as lung cancer and emphysema.
Dynamic multi-modal x-ray imaging. This project aims to create sensitive new methods of x-ray imaging that capture multiple image modalities with a single snapshot. Conventional x-ray imaging is widely used in a range of industries, but captures only a fraction of the rich information that is available in the x-ray wavefield. This project expects to extract additional image modalities to reveal x-ray-transparent features, and detect microscopic textures. By combining these capabilities with the ....Dynamic multi-modal x-ray imaging. This project aims to create sensitive new methods of x-ray imaging that capture multiple image modalities with a single snapshot. Conventional x-ray imaging is widely used in a range of industries, but captures only a fraction of the rich information that is available in the x-ray wavefield. This project expects to extract additional image modalities to reveal x-ray-transparent features, and detect microscopic textures. By combining these capabilities with the ability to capture images of a moving sample, this project will enable innovative biomedical and materials research studies, and develop new imaging technologies for use in security, hospitals and manufacturing. New methods of x-ray imaging will have wide-ranging benefits for society, the economy and healthcare.Read moreRead less
Advanced imaging technology for measuring pulmonary form and function. Studies of the lung are often limited by difficulties associated with imaging the complex network of airways with conventional techniques. This project will develop novel phase contrast image x-ray imaging technologies to enable quantitative measurements of lung structure and function for studying lung development and assessing lung health.