Innovations In Cancer Imaging And Targeted Radiotherapy To Improve Human Health
Funder
National Health and Medical Research Council
Funding Amount
$926,980.00
Summary
Through a process of discovery, development and investigation we will create medical devices and methods to improve cancer imaging and targeted radiotherapy. Successful completion of this program will directly impact on the treatment and lives of Australian cancer patients in the foreseeable future.This program will substantially build research capacity and productivity within Australia, raise Australia’s profile in cancer research and foster international collaboration.
Development Of A Non-invasive Magnetic Resonance Based Cartilage Damage Assessment Technique
Funder
National Health and Medical Research Council
Funding Amount
$556,131.00
Summary
This project will develop automated methods for the extraction of 3D maps of cartilage, bone and other anatomy from high field Magnetic Resonance Images of joints in the body.
MR Hip Intervention And Planning System To Enhance Clinical And Surgical Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$668,069.00
Summary
Degenerative hip disorders and osteoarthritis are a major cause of chronic pain and disability. This project will develop a software tool that allows clinicians to assess, monitor and plan patient treatment using magnetic resonance imaging. It will be the first tool that models joint motion using assessments of bone, cartilage and labral tissue. This will help guide treatment selection and improve outcomes from hip surgeries performed on over 20,000 Australians each year.
Harnessing Imaging And IT Strategies To Expedite Targeted Treatment And Improve Outcomes In Cerebrovascular Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,914,215.00
Summary
This project will expand on my 25+ years of research in combining neuroimaging methods such as CT and MRI with nascent software tools to better target and coordinate treatment and achieve improved outcomes in cerebrovascular diseases such as stroke. We will develop & improve new CT and MRI methods and leverage latest advances in computer science, such as deep learning and mobile phone app technology, to achieve faster and more accurate identification of patients who can benefit from treatment.
Improving Patient Safety In Radiation Therapy With The Watchdog Real-time Treatment Delivery Verification System
Funder
National Health and Medical Research Council
Funding Amount
$593,742.00
Summary
Radiation therapy is a highly effective cancer treatment with extremely high doses delivered using very complex treatment machines. Unfortunately errors have occurred resulting in cases of patient death and mistreatment. We have developed a novel method to assess the treatment delivery in real-time to prevent errors. The method uses imaging devices that are already present on the treatment machine meaning that this method could have a major impact on patient safety in modern radiation therapy.
Biofocussed Prostate Cancer RadioTherapy (BiRT): A Personalised Approach To Delivering The Right Dose To The Right Place
Funder
National Health and Medical Research Council
Funding Amount
$753,565.00
Summary
We propose a new approach to treating prostate cancer with radiotherapy to move from the standard whole prostate treatment to a personalised treatment that varies radiation intensity throughout the prostate. We will mathematically combine features that influence radiotherapy effect from advanced imaging, clinical and biopsy information. This model will map out the radiotherapy dose required at each part of the prostate, to maximise killing of the cancer whilst minimising harm to normal tissue
Dynamic In Vivo Size & Shape Measurement Of The Human Upper Airway Using Endoscopic Long-range Optical Coherence Tomogra
Funder
National Health and Medical Research Council
Funding Amount
$184,250.00
Summary
This project will fund the construction of a clinically deployable prototype device to measure changes in upper airway size and shape in patients with obstructive sleep apnoea. We have recently developed and validated a technique based on endoscopic optical coherence tomography (OCT). Preliminary in vivo studies have been performed in the human upper airway and the results published. To our knowledge, this is the only such system world-wide capable of making these important measurements. The tec ....This project will fund the construction of a clinically deployable prototype device to measure changes in upper airway size and shape in patients with obstructive sleep apnoea. We have recently developed and validated a technique based on endoscopic optical coherence tomography (OCT). Preliminary in vivo studies have been performed in the human upper airway and the results published. To our knowledge, this is the only such system world-wide capable of making these important measurements. The technique has wide commercially applicability as it can be used to measure the internal dimensions of any hollow organ system.Read moreRead less
Towards Predicting Brain Deformations For Image-guided Neurosurgery
Funder
National Health and Medical Research Council
Funding Amount
$304,281.00
Summary
We will significantly improve the efficiency of image-guided neurosurgery for brain tumours by creating a novel system to improve intra-operative visualisation and navigation utilising realistic prediction of brain deformations based on a biomechanical model. The system will create an augmented reality visualisation of the intra-operative configuration of the patient's brain merged with high resolution pre-operative imaging data in order to better localise the tumour and critical healthy tissues ....We will significantly improve the efficiency of image-guided neurosurgery for brain tumours by creating a novel system to improve intra-operative visualisation and navigation utilising realistic prediction of brain deformations based on a biomechanical model. The system will create an augmented reality visualisation of the intra-operative configuration of the patient's brain merged with high resolution pre-operative imaging data in order to better localise the tumour and critical healthy tissues.Read moreRead less