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Prevalence Of Genital HPV Infection In Males Following Introduction Of Universal Male HPV Vaccination
Funder
National Health and Medical Research Council
Funding Amount
$320,891.00
Summary
As Australia is the first and only country to implement a free universal school based male human papillomavirus (HPV) vaccination program (in 2013), this project has the unique opportunity to be first to study to assess the effectiveness of the male HPV vaccination program in Australia by measuring a change in the prevalence of HPV among young (aged 17-20) heterosexual and homosexual men following the implementation of the vaccination program.
Reducing Disparities In Cervical Cancer Incidence For Aboriginal And Torres Strait Islander Women Through Screening And Vaccination
Funder
National Health and Medical Research Council
Funding Amount
$329,768.00
Summary
This program of research will aim to reduce cervical cancer incidence for Indigenous women by developing and trialling health systems interventions to increase cervical screening participation and HPV vaccination coverage. This research will be led by an Indigenous researcher with Indigenous people and for Indigenous people.
The Prevalence, Incidence And Natural History Of Anal Cellular Abnormalities In Mature-aged Homosexual Men
Funder
National Health and Medical Research Council
Funding Amount
$144,725.00
Summary
Anal cancer is one of the most common cancers in homosexual men and rates in Australia are now higher than those of cervical cancer prior to the introduction of routine cervical screening in women. The Mature Aged Gay MenÍs Anal Health Study will enrol 1000 men over 45 years old and follow them for up to 5 years to investigate the progression of anal pre-cancerous lesions in men and the potential of a screening program to allow early detection of these lesions.
Immune Modulatory Interventions In People With HIV And Cancer: Prevention, Treatment, And Implications For HIV Eradication.
Funder
National Health and Medical Research Council
Funding Amount
$344,644.00
Summary
People with HIV are at increased risk of many cancers. New therapies that target the immune system may be useful in treating these cancers, and may also target the cells where HIV persists thereby assisting in eradication of HIV. This research program includes three clinical studies in people with HIV and cancer: one to learn more about their immunity; one to prevent, and one to treat certain cancers by modulating the immune system. Each also explores any effect on HIV eradication.
Human Papillomavirus Infection In Gay Australian Men: Natural History Of The Serological Response And The Relationship Between Seropositivity, Risk Factors And Anal Disease
Funder
National Health and Medical Research Council
Funding Amount
$185,822.00
Summary
Anal cancer rates are increasing globally. Gay men are 20 times more likely than other men to develop anal cancer and for those people living with HIV, the risk is even higher. Human papillomaviruses (HPV) have been shown to cause anal cancer. This research explores the natural history of anal HPV infection and the relationship between HPV infection and anal cancer. These results will potentially inform the development of guidelines for an anal cancer screening program for gay Australian men.
Anogenital Human Papillomavirus Infection And Its Outcomes In Men
Funder
National Health and Medical Research Council
Funding Amount
$333,433.00
Summary
Anal human papillomavirus (HPV) infection is common in homosexual men. Low risk types cause anal warts and high risk types of HPV cause anal cancer. This study will determine incidence and risk factors for HPV infection in a cohort of young homosexual men, the association of anal warts treatment with HIV risk, and the specific association of HPV subtypes with anal cancer. The findings of this research will help delineate the potential benefits of HPV vaccination in this population.
Understanding The Establishment Of HIV Reservoirs And Development Of HIV Eradication Strategies
Funder
National Health and Medical Research Council
Funding Amount
$380,891.00
Summary
Understanding why, when, how and at what pace the HIV virus hides and establishes itself in one's body will allow us to design new ways for preventing and eliminating this reservoir of hidden HIV. As a clinician scientist in HIV and infectious diseases, I will drive clinical studies to explore the kinetics of HIV in patients who recently acquired HIV, those who start HIV treatment early, and those chronically infected with HIV so as to investigate novel means to minimise HIV hiding spots.