Development of disulphide-rich peptides for drug design. Peptides are an outstanding source of potential drug leads. This project seeks to build on earlier breakthroughs by developing stable, peptide-based drugs to combat cancer and autoimmune diseases. The peptides, derived from natural sources, are anticipated to provide drug leads that can ultimately lead to treatments for these diseases.
Coastal governance. This project aims to discover coastal governance approaches that embrace vulnerability and change. Current coastal management approaches are failing as existing threats intensify and new threats emerge. This project expects to generate knowledge on diverse vulnerabilities, with insights advancing the disciplines of human geography and public policy through improved understanding of the relationships between people, place and change. This is expected to support ongoing economi ....Coastal governance. This project aims to discover coastal governance approaches that embrace vulnerability and change. Current coastal management approaches are failing as existing threats intensify and new threats emerge. This project expects to generate knowledge on diverse vulnerabilities, with insights advancing the disciplines of human geography and public policy through improved understanding of the relationships between people, place and change. This is expected to support ongoing economic, environmental, social and cultural benefits that are derived from the Australian coast.
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Transforming the outer suburbs through master planned estates: a governmental challenge. Master planned estates are becoming more common on the outer suburbs of capital cities and the developers of these estates are required to plan and manage a whole range of services. This project examines the role that private actors play in 'governing' suburban estates alongside traditional forms of government and the challenges that ensue.
Normalising Ability Diversity through Career Transitions:Disability at Work. This project aims to investigate how the higher education sector can better support people with disabilities to transition from economic exclusion to work. One in five Australians have a disability and of these 47.3% are not employed. This is a significant issue with regulatory failures and challenges often affecting rights to education and work being exercised on an equal basis. This project seeks to examine internatio ....Normalising Ability Diversity through Career Transitions:Disability at Work. This project aims to investigate how the higher education sector can better support people with disabilities to transition from economic exclusion to work. One in five Australians have a disability and of these 47.3% are not employed. This is a significant issue with regulatory failures and challenges often affecting rights to education and work being exercised on an equal basis. This project seeks to examine international legal norms, theories and strategic and operational practices in the higher education sector. Expected outcomes include advances in scholarship on ableism, informed policy reform, and transferable operational processes for the education and employment sectors, to improve the transition of people with disabilities to work.Read moreRead less
Defining disease: Addressing the problem of overdiagnosis. This project will investigate and define the limits of physical disease, to answer questions about when a presentation is a disease, and when it is simply a risk factor or mild condition. The ensuing account of disease will make a practical contribution to growing international concern about asymptomatic people being diagnosed and treated for conditions that will not cause any health problems ("overdiagnosis"). The research will provide ....Defining disease: Addressing the problem of overdiagnosis. This project will investigate and define the limits of physical disease, to answer questions about when a presentation is a disease, and when it is simply a risk factor or mild condition. The ensuing account of disease will make a practical contribution to growing international concern about asymptomatic people being diagnosed and treated for conditions that will not cause any health problems ("overdiagnosis"). The research will provide normative grounds for evaluating disease claims. Results will reduce the harm caused by people receiving treatment that they do not require, make a practical contribution to debates about the scope of health care, and yield findings that can help to reduce the cost-burdens associated with overdiagnosis.Read moreRead less
Caged lanthanides for use in photo-dynamic therapy and near infra-red imaging. The early detection and effective treatment of cancer are two critical factors which determine survivability. This project will provide improved drugs for photo-dynamic therapy and develop emissive probes for near infra-red imaging to allow better discrimination between healthy and diseased tissue and improve subsequent treatment.
Indigenous solutions to global challenges in the Pacific Islands. The global COVID 19 pandemic represents a unique opportunity to understand the nature and potential of Indigenous sustainable development in Pacific Island communities, where Indigenous practices have been central in responses to closed borders and industry downturns. This project proposes to analyse the efficacy and cultural value of new, pandemic-era Indigenous sustainable development initiatives in sustaining island communities ....Indigenous solutions to global challenges in the Pacific Islands. The global COVID 19 pandemic represents a unique opportunity to understand the nature and potential of Indigenous sustainable development in Pacific Island communities, where Indigenous practices have been central in responses to closed borders and industry downturns. This project proposes to analyse the efficacy and cultural value of new, pandemic-era Indigenous sustainable development initiatives in sustaining island communities. It aims to culminate in a novel geographic theory of Indigenous sustainable development, and to identify new opportunities to support the expansion of Indigenous sustainable development. This should better enable the Pacific Islands region to respond to climate change, pandemics and other global challenges.Read moreRead less
Socially just schooling: a cross-cultural analysis of gender, cultural diversity and social change within Australia and the UK. The study will examine issues of gender justice, cultural diversity and schooling. Through cross-cultural insight developed from analysis of schools in Australia and the UK, the study will enhance policy and practice associated with socially just schooling.
The internationalisation of nationalist populism. This project aims to explain the rising international cooperation between nationalist populists in democracies across the world. It expects to generate new knowledge about how and why these forces now work together to oppose common targets such as multilateral institutions, free trade and liberal democracy. Expected outcomes of this project include a sophisticated, evidence-based understanding of the dynamics and effects of contemporary nationali ....The internationalisation of nationalist populism. This project aims to explain the rising international cooperation between nationalist populists in democracies across the world. It expects to generate new knowledge about how and why these forces now work together to oppose common targets such as multilateral institutions, free trade and liberal democracy. Expected outcomes of this project include a sophisticated, evidence-based understanding of the dynamics and effects of contemporary nationalist populist cooperation. Given Australia's commitment to promoting good governance and strong democratic institutions, in addition to the interest overseas nationalist populists have shown in helping likeminded movements in Australia, the project will provide significant benefits for policymakers.Read moreRead less
New data-driven mathematical models of collective cell motion. Cancer and chronic wounds are a national, and indeed, international health problem set to worsen as our population ages. Predictive and interpretive tools are required to improve our understanding of collective cell migration in relation to cancer and chronic wounds. This project will produce new validated mathematical tools for predicting collective cell migration in a general framework that can deal with application-specific detail ....New data-driven mathematical models of collective cell motion. Cancer and chronic wounds are a national, and indeed, international health problem set to worsen as our population ages. Predictive and interpretive tools are required to improve our understanding of collective cell migration in relation to cancer and chronic wounds. This project will produce new validated mathematical tools for predicting collective cell migration in a general framework that can deal with application-specific details, such as the role of cell shape and cell size. Although cell shape and size are known to affect collective cell migration, standard mathematical models ignore these details. This project will produce new predictive mathematical modelling tools that are validated by new experimental data. Read moreRead less