Discovery Early Career Researcher Award - Grant ID: DE200100259
Funder
Australian Research Council
Funding Amount
$417,755.00
Summary
Hacking Housing: Technologies, processes and practices of housing futures. Australian’s experiences of housing are changing due to rising housing unaffordability, uncertain employment prospects & digital disruptions to housing markets. A diverse housing system is resulting, as housing providers & consumers innovate with novel housing models & practices to find solutions to housing problems. Contemporary housing thinking cannot grasp this reshaping of housing. The project aims to advance a new co ....Hacking Housing: Technologies, processes and practices of housing futures. Australian’s experiences of housing are changing due to rising housing unaffordability, uncertain employment prospects & digital disruptions to housing markets. A diverse housing system is resulting, as housing providers & consumers innovate with novel housing models & practices to find solutions to housing problems. Contemporary housing thinking cannot grasp this reshaping of housing. The project aims to advance a new conceptual framework & innovative methodologies to understand the new housing landscape as digital, rented & shared. It expects to generate new empirical knowledge using digital methodologies & grow international research networks. This should provide benefits such as evidence to inform policy & a digital methods toolkit.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100021
Funder
Australian Research Council
Funding Amount
$4,999,540.00
Summary
ARC Research Hub to Combat Antimicrobial Resistance. The ARC ITRP Research Hub to Combat Antimicrobial Resistance takes on the global challenge of antimicrobial resistance (AMR) for Australia through a world-first partnership between industry, researchers, and end users. The AMR Hub fosters a pre-commercialisation environment to address both social and laboratory-based preclinical challenges to provide a highly integrated diagnostic, pharmaceutical and end user solution to the problem of AMR. A ....ARC Research Hub to Combat Antimicrobial Resistance. The ARC ITRP Research Hub to Combat Antimicrobial Resistance takes on the global challenge of antimicrobial resistance (AMR) for Australia through a world-first partnership between industry, researchers, and end users. The AMR Hub fosters a pre-commercialisation environment to address both social and laboratory-based preclinical challenges to provide a highly integrated diagnostic, pharmaceutical and end user solution to the problem of AMR. A goal of the Hub is to support the development of new molecular diagnostic technology, improve the processes for identifying potential antibiotic compounds and assess and advise on antimicrobial stewardship with a vision to transform social and health outcomes globally.Read moreRead less
Detecting, preventing and responding to image-based abuse. This project aims to investigate the efficacy of digital tools and interventions to detect, prevent and respond to image-based abuse (the non-consensual creation or distribution of intimate images). Through a digital ethnography, victim and stakeholder interviews, online surveys, and an AI chatbot, the project expects to generate evidence and theory on both image-based abuse and internet governance. The expected outcomes include: increas ....Detecting, preventing and responding to image-based abuse. This project aims to investigate the efficacy of digital tools and interventions to detect, prevent and respond to image-based abuse (the non-consensual creation or distribution of intimate images). Through a digital ethnography, victim and stakeholder interviews, online surveys, and an AI chatbot, the project expects to generate evidence and theory on both image-based abuse and internet governance. The expected outcomes include: increased understanding of the responsibility of digital platforms and the drivers of image-based abuse; improved platform and service responses; enhanced industry and scholarly collaborations; and harm reduction. Expected benefits include improved laws, polices and practices to tackle image-based abuse.Read moreRead less
Radio-magnetic nanoparticles as bimodal positron emission tomography/magnetic resonance imaging contrast agents for dendritic cell tracking. Biomedical imaging is limited by a lack of commercial dual-mode contrast agents, which may be simultaneously used for magnetic resonance (MR) and positron emission tomography (PET) imaging. This project will develop a nanotechnology-based biocompatible dual-mode contrast agent for simultaneous PET and MR imaging, reducing associated side effects.
Discovery Early Career Researcher Award - Grant ID: DE140101553
Funder
Australian Research Council
Funding Amount
$395,220.00
Summary
A flexible virus-like particle delivery platform for next-generation vaccines. Murine polyomavirus (MPyV) capsid proteins self-assemble into spherical protein shells approximately 45 nm in diameter. Such virus-like particles (VLPs) are of considerable interest as bionanotechnological tools. The unique flexibility provided by MPyV VLPs will be exploited by exploring the ability of the interior cavity to retain bioactive cargos while engineering novel functionality on the exterior surface by 'mix- ....A flexible virus-like particle delivery platform for next-generation vaccines. Murine polyomavirus (MPyV) capsid proteins self-assemble into spherical protein shells approximately 45 nm in diameter. Such virus-like particles (VLPs) are of considerable interest as bionanotechnological tools. The unique flexibility provided by MPyV VLPs will be exploited by exploring the ability of the interior cavity to retain bioactive cargos while engineering novel functionality on the exterior surface by 'mix-and-match' assembly of VLPs from modified components. As a proof of concept for next-generation vaccines that stimulate much needed, broadly protective responses against infectious diseases, model antigens will be delivered to specific immune cells using this nano-container.Read moreRead less
Coach My Ride: Mentorable Interfaces to support Older Australians' Mobility. This project aims to co-design new interfaces to support older Australians to collaboratively learn the use of automated vehicles. We will seek to understand the needs, expectations, and challenges of urban and rural residents, and the peer support strategies they deploy to learn technology. Mobility is key to the wellbeing of older people, but automated vehicles that are too complex will fail to deliver their promise o ....Coach My Ride: Mentorable Interfaces to support Older Australians' Mobility. This project aims to co-design new interfaces to support older Australians to collaboratively learn the use of automated vehicles. We will seek to understand the needs, expectations, and challenges of urban and rural residents, and the peer support strategies they deploy to learn technology. Mobility is key to the wellbeing of older people, but automated vehicles that are too complex will fail to deliver their promise of independent ageing. Outcomes will be a new theory of collaborative learning and new mentorable interfaces to allow older adults to mentor each other to access and use new mobility solutions. This will contribute to narrow the digital and mobility gap improving the independence, safety and wellbeing of ageing Australians.Read moreRead less
Framing and Enabling Children’s Active Play using Novel Technology. This project aims to address inactivity in the 3-5 age group through understanding and exploring innovative interactive active play experiences for children, with a view to increasing their physical activity over the long term. This project will be based on empirical research with real children undertaking real interactive experiences in real contexts, in order to understand issues around sustained engagement with these types of ....Framing and Enabling Children’s Active Play using Novel Technology. This project aims to address inactivity in the 3-5 age group through understanding and exploring innovative interactive active play experiences for children, with a view to increasing their physical activity over the long term. This project will be based on empirical research with real children undertaking real interactive experiences in real contexts, in order to understand issues around sustained engagement with these types of systems. We will design and develop solutions that may address the issues and test those interventions in a longitudinal manner. The outcome will be a framework which can be applied in a variety of situations and modalities by designers and developers of such systems, and feed into childhood technology guidelines.
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Discovery Early Career Researcher Award - Grant ID: DE150101518
Funder
Australian Research Council
Funding Amount
$345,000.00
Summary
Cellular responses to nanoparticles from cells on micropatterned surfaces. The mechanisms underlying cell-nanoparticle interactions remain largely unknown. It has hampered the design and development of innovative nano devices to be used for drug delivery, biomarkers and diagnostics. This project aims to explore the influences of cell size, density, geometry, intercellular communication and substrate properties on cell-nanoparticle interactions. A micropatterning technology is applied to precisel ....Cellular responses to nanoparticles from cells on micropatterned surfaces. The mechanisms underlying cell-nanoparticle interactions remain largely unknown. It has hampered the design and development of innovative nano devices to be used for drug delivery, biomarkers and diagnostics. This project aims to explore the influences of cell size, density, geometry, intercellular communication and substrate properties on cell-nanoparticle interactions. A micropatterning technology is applied to precisely control cell behaviour and provide a novel in vitro cellular model for nanoparticle studies. This project aims to significantly improve the understanding of cell-nanoparticle interactions to provide new insight into nanoparticle design and improve the efficacy of nano devices.Read moreRead less
Augmented Sociality: Enabling a Socialised Experience of Augmented Reality. This project will explore new socialised uses of Augmented Reality (AR) that expand creativity, social relations, and participation. We seek to better understand how AR content can be leveraged by people to create their own new ways of learning, collaborating, and relating with each other. To do so we will study and prototype new tools and platforms to allow non-experts to create their own AR media. We aim to enable peop ....Augmented Sociality: Enabling a Socialised Experience of Augmented Reality. This project will explore new socialised uses of Augmented Reality (AR) that expand creativity, social relations, and participation. We seek to better understand how AR content can be leveraged by people to create their own new ways of learning, collaborating, and relating with each other. To do so we will study and prototype new tools and platforms to allow non-experts to create their own AR media. We aim to enable people of all ages, education, and background, to imagine and create, and not just passively consume, AR contents, services, and applications. We will generate new applications of AR, a new platform to collaboratively create these applications, and a new theory of 'Augmented Sociality' to guide AR design.
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Autotransporter folding: insights advancing recombinant protein production. Imagine a world in which any protein could be produced using a single production platform. This project aims to make this a reality by reengineering autotransporters, a large family of bacterial virulence factors with a modular structure that makes them amenable to rational design. The project plans to examine the structures and folding behaviour of autotransporters and reengineered derivatives fused to target heterologo ....Autotransporter folding: insights advancing recombinant protein production. Imagine a world in which any protein could be produced using a single production platform. This project aims to make this a reality by reengineering autotransporters, a large family of bacterial virulence factors with a modular structure that makes them amenable to rational design. The project plans to examine the structures and folding behaviour of autotransporters and reengineered derivatives fused to target heterologous proteins using biochemical, biophysical, and structural methods. It is expected that this project will provide fundamental insights into factors that dictate autotransporter folding and stability, which may enhance recombinant protein production and drive discovery of strategies to prevent autotransporter-mediated infection.Read moreRead less