A Study Of The Relationship Between Vitamin D Status And The Severity And Outcomes Of Chronic Non-cholestatic Liver Disease
Funder
National Health and Medical Research Council
Funding Amount
$133,351.00
Summary
Vitamin D deficiency is associated with common and severe conditions such as cancer, cardiovascular disease, autoimmune disease and diabetes. Recent studies suggest that vitamin D deficiency also worsens the severity and prognosis of chronic liver disease and that vitamin D replacement may improve outcomes. This research will further investigate the relationship of vitamin D deficiency to liver disease caused by the common conditions hepatitis B and C and non-alcoholic fatty liver disease and th ....Vitamin D deficiency is associated with common and severe conditions such as cancer, cardiovascular disease, autoimmune disease and diabetes. Recent studies suggest that vitamin D deficiency also worsens the severity and prognosis of chronic liver disease and that vitamin D replacement may improve outcomes. This research will further investigate the relationship of vitamin D deficiency to liver disease caused by the common conditions hepatitis B and C and non-alcoholic fatty liver disease and the impact of vitamin D replacement.Read moreRead less
The Role Of Hepatitis B E Antigen Status In The Natural History And Therapeutic Outcomes Of Chronic Hepatitis B
Funder
National Health and Medical Research Council
Funding Amount
$88,342.00
Summary
Hepatitis B can cause liver failure and cancer and affects between 90,000 and 160,000 people in Australia. Effective treatments are available but these cannot eradicate the virus. We will study the natural history to try and identify reasons why some people develop severe liver disease and others do not and why some patients respond to treatment and others do not. We will also look at of the best ways to monitor patients with blood tests whether they are receiving treatment or not.