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Research Topic : heart development
Scheme : NHMRC Strategic Awards
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  • Funded Activity

    Detection And Management Of Depression In General Practice Patients With Chronic Manifestations Of Ischaemic Heart Disea

    Funder
    National Health and Medical Research Council
    Funding Amount
    $499,797.00
    Summary
    This research will investigate the impact of ischemic heart disease on the prevalence and severity of patients with depression. This will be done via a 12 month general practice based program of 1) systematic screening for depression 2) informing general practitioners of best-practice guidelines for management of depression in these patients, and 3) providing the treating general practitioner with patient-specific, psychiatric advice.
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    Funded Activity

    Provision Of Secondary Cardiac Preventive Australian General Practice

    Funder
    National Health and Medical Research Council
    Funding Amount
    $499,513.00
    Summary
    This study will provide a comprehensive description of secondary preventative activities for patients with ischaemic heart disease, with the aim of determining those factors that can most contribute to reducing the increased risk of further events which they experience, and thereby reducing the burden of this disease.
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    Funded Activity

    Body Composition Changes In Cardiac Cachexia: Pathophysiology, Quantification And Approaches To Therapy

    Funder
    National Health and Medical Research Council
    Funding Amount
    $120,000.00
    Summary
    Cachexia is weight loss and weakness caused by disease, or as a side effect of illness. Congestive heart failure is a common cardiovascular condition that is accompanied by high mortality (up to 50% over 2 years) and considerable suffering. People with congestive heart failure often develop cachexia. This project will explore the mechanisms responsible for the development of cachexia using an animal model of cardiac cachexia that the researchers have developed. It will be complemented by an exam .... Cachexia is weight loss and weakness caused by disease, or as a side effect of illness. Congestive heart failure is a common cardiovascular condition that is accompanied by high mortality (up to 50% over 2 years) and considerable suffering. People with congestive heart failure often develop cachexia. This project will explore the mechanisms responsible for the development of cachexia using an animal model of cardiac cachexia that the researchers have developed. It will be complemented by an examination of the effects of exercise on measures of cachexia in patients with congestive heart failure. The researchers believe that this study will supply valuable new information about the development of cachexia and lead to new therapies for this syndrome.
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    Funded Activity

    Sadness And Heart Disease

    Funder
    National Health and Medical Research Council
    Funding Amount
    $29,650.00
    Summary
    This project will examine the acceptability and validity of a depression screening tool for use with Aboriginal and Torres Strait Islander patient with ischaemic heart disease, and concurrently determine depression prevalence in the sample population attending an urban Aboriginal community controlled health service.
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    Funded Activity

    A Ramdomised Trial Of Telephone Support For Chronic Heart Failure Patients At High Rish Of Re-hospital

    Funder
    National Health and Medical Research Council
    Funding Amount
    $347,750.00
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    Funded Activity

    Oxygen To Relieve Dyspnoea In Non-hypoxaemic Patients With End-stage Heart Failure

    Funder
    National Health and Medical Research Council
    Funding Amount
    $445,658.00
    Summary
    Chronic heart failure is a cause of suffering and a major cause of death in the Australian community. Patients who have chronic heart failure suffer from a range of symptoms that severely impacts every aspect of their life. One of the most common and distressing symptoms is breathlessness. As people with heart failure near death, their breathlessness may worsen not only in terms of its frequency, but also in its intensity. This worsening of symptoms is a source of great distress, both to patient .... Chronic heart failure is a cause of suffering and a major cause of death in the Australian community. Patients who have chronic heart failure suffer from a range of symptoms that severely impacts every aspect of their life. One of the most common and distressing symptoms is breathlessness. As people with heart failure near death, their breathlessness may worsen not only in terms of its frequency, but also in its intensity. This worsening of symptoms is a source of great distress, both to patients as well as their carers and family. Breathlessness is also the most common cause of admission to hospital for patients. A key strategy for managing this distressing symptom in the home is the supply of oxygen. However, due to a lack of scientific evidence for the benefit of home oxygen for people with heart failure, who do not necessarily have low levels of oxygen, it is very difficult for clinicians to access this therapy for their patients. This study seeks to assess if a specific breathlessness action plan alone or if the addition of either oxygen or air can relieve this distressing symptom. The scientific evaluation of these strategies will assist in improving the palliative care of people with chronic heart failure.
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    Funded Activity

    Strengthing Health Literacy Among Indigenous People Living With Cardiovascular Disease, Their Familes And Health Care Pr

    Funder
    National Health and Medical Research Council
    Funding Amount
    $506,933.00
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    Funded Activity

    Which Heart Failure Intervention Is Most Cost-effective And Consumer Friendly In Reducing Hospital Care: The Which

    Funder
    National Health and Medical Research Council
    Funding Amount
    $921,640.00
    Summary
    Chronic heart failure (CHF) is a costly, debilitating and deadly condition that has reached near epidemic proportions in Australia. In the absence of a permanent cure for CHF, the number of people affected by CHF has risen beyond 350,000 and is expected to increase by 20-30% in the next 20 years. We recently reviewed the benefits of applying nurse-led, CHF management programs (CHF-MPs) to typically old and fragile patients, in whom recurrent hospital admissions and a premature death are common. .... Chronic heart failure (CHF) is a costly, debilitating and deadly condition that has reached near epidemic proportions in Australia. In the absence of a permanent cure for CHF, the number of people affected by CHF has risen beyond 350,000 and is expected to increase by 20-30% in the next 20 years. We recently reviewed the benefits of applying nurse-led, CHF management programs (CHF-MPs) to typically old and fragile patients, in whom recurrent hospital admissions and a premature death are common. We confirmed the results of pioneering Australian research that CHF-MPs dramatically improve health outcomes in CHF. CHF-MPs now form part of the recommended gold-standard management of CHF. However, we also have evidence that only a small proportion of patients are exposed to a CHF-MP in Australia. Residual issues such as consumer preference and the cost of applying these programs are hindering their wide-spread application. The WHICH? Study addresses this _road block� to implementing a potentially valuable health care service by tackling a number of critical issues: which form of CHF-MP (home or specialist clinic-based follow-up), will produce the best health outcomes, save the most money and meet the needs of consumers at the same time? To answer this question, we will undertake a randomised, head-to-head study of a home versus clinic-based CHF-MP, in 1000 recently hospitalised CHF patients recruited from SA, VIC, NSW and QLD. Patterns and of health care and consumer preferences and quality of life will then be compared for these two different forms of CHF-MP from a combined health economic, health policy and consumer perspective to determine the best form of CHF-MP to be applied. A _consensus� vision for applying an Australia-wide service will then be developed. The potential impact of the results of the study will then be modelled on the status of Australian CHF-MPs in the year 2010 and a blue-print for action devised.
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    Funded Activity

    Improving The Cost-effectiveness Of Health Services For The Prevention And Treatment Of Coronary Heart Disease

    Funder
    National Health and Medical Research Council
    Funding Amount
    $206,383.00
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    Funded Activity

    Improving Care Of The Dying With Chronic Heart Failure

    Funder
    National Health and Medical Research Council
    Funding Amount
    $130,000.00
    Summary
    Chronic heart failure is increasing in prevalence and is primarily a condition of ageing. Although chronic heart failure has worse outcomes than many cancers, patients are often denied the benefits of palliative care with its emphasis on symptom management, spirituality, emotional health and focus on family issues. This project seeks to assess the state of knowledge in Australia related to palliative care in chronic heart failure. Guidelines and care maps appropriate to Australian conditions wil .... Chronic heart failure is increasing in prevalence and is primarily a condition of ageing. Although chronic heart failure has worse outcomes than many cancers, patients are often denied the benefits of palliative care with its emphasis on symptom management, spirituality, emotional health and focus on family issues. This project seeks to assess the state of knowledge in Australia related to palliative care in chronic heart failure. Guidelines and care maps appropriate to Australian conditions will be developed and their usefulness assessed in improving care of patients and their families.
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