Chromatic Inputs to Cortical Receptive Fields in Primates. The human eye contains three kinds of receptors for daytime vision, named blue, green and red cones for their sensitivity to different regions of the visible spectrum. It is known that blue cones contribute to brain pathways for colour vision, but recent data suggest there is also 'cross-talk' of blue cone signals to pathways for motion and high-acuity vision. This project comprises precise measurement of blue cone signals, and anatomica ....Chromatic Inputs to Cortical Receptive Fields in Primates. The human eye contains three kinds of receptors for daytime vision, named blue, green and red cones for their sensitivity to different regions of the visible spectrum. It is known that blue cones contribute to brain pathways for colour vision, but recent data suggest there is also 'cross-talk' of blue cone signals to pathways for motion and high-acuity vision. This project comprises precise measurement of blue cone signals, and anatomical tracing of blue cone pathways, in a primate model for human vision. The data will improve our basic knowledge of how the brain processes sensory signals.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0452971
Funder
Australian Research Council
Funding Amount
$102,900.00
Summary
Optical imaging of brain activity: Studies of the neural basis of sensory perception, plasticity and behaviour. Basic to the understanding of the brain is to know how the overall architecture of the nervous system relates to its function. We propose to study this by directly visualising the regions that are functionally active in the living brains of animals, down to resolution limits of less than 100 micrometres. Such "optical imaging" will be done by recording light reflected from the surfac ....Optical imaging of brain activity: Studies of the neural basis of sensory perception, plasticity and behaviour. Basic to the understanding of the brain is to know how the overall architecture of the nervous system relates to its function. We propose to study this by directly visualising the regions that are functionally active in the living brains of animals, down to resolution limits of less than 100 micrometres. Such "optical imaging" will be done by recording light reflected from the surface of the brain, which in turn depends upon activity-dependent intrinsic signals (eg. degree of oxygenation of haemoglobin). These signals will be recorded by a special camera and amplified using the requested system.Read moreRead less
Position perception, attention, object motion, and action. The research will achieve a deeper understanding of the neural processing of the visual perception of position, and of the associated behavioural limits. This will provide a foundation for the development of a range of technologies to assist disabled and elderly people. The results will help reveal the link between the perception of moving objects and the capacity for visually guided movement. This link will benefit areas such as enginee ....Position perception, attention, object motion, and action. The research will achieve a deeper understanding of the neural processing of the visual perception of position, and of the associated behavioural limits. This will provide a foundation for the development of a range of technologies to assist disabled and elderly people. The results will help reveal the link between the perception of moving objects and the capacity for visually guided movement. This link will benefit areas such as engineering of vehicles and road systems, and the design of telepresence systems. The first applications are likely to be in the rehabilitation of brain injury and the decline of mental function with age.Read moreRead less
Complex Motion Processing in Primate Visual Cortex. As we move through the world, a dynamic visual image is projected onto our retinas. The pattern of movement in the retinal image contains information about three-dimensional structure in the environment and the time of impending collisions. Our visual systems are expert at exploiting this information, enabling us to navigate through complex visual environments at a level far beyond the most sophisticated artificial systems. We plan to investiga ....Complex Motion Processing in Primate Visual Cortex. As we move through the world, a dynamic visual image is projected onto our retinas. The pattern of movement in the retinal image contains information about three-dimensional structure in the environment and the time of impending collisions. Our visual systems are expert at exploiting this information, enabling us to navigate through complex visual environments at a level far beyond the most sophisticated artificial systems. We plan to investigate complex motion processing in the primate brain by recording the responses of neurons in identified regions of the visual cortex of macaque monkeys to a range of behaviourally relevant motion stimuli.Read moreRead less
Motion and Spatial Coding in Vision. The results of this project will have implications for the design and implementation of artificial visual systems. Completion of this project will depend upon international collaboration - forging links between a young Australian investigator and outstanding overseas scientists as well as providing excellent training opportunities. Subsequent publication of the research in top-ranking international journals will further promote Australian science abroad.
Reconciling perceptual and cognitive accounts of dyslexia: The neural rate deficit hypothesis. The proposed research will form part of a co-ordinated program to understand the causes of dyslexia, a disorder that affects a large number of children and often persists into adulthood. It complements parallel efforts to elucidate the genetic basis of dyslexia, the heterogeneity and subtypes of dyslexia, and the developmental precursors to the disorder. This research will inform early intervention and ....Reconciling perceptual and cognitive accounts of dyslexia: The neural rate deficit hypothesis. The proposed research will form part of a co-ordinated program to understand the causes of dyslexia, a disorder that affects a large number of children and often persists into adulthood. It complements parallel efforts to elucidate the genetic basis of dyslexia, the heterogeneity and subtypes of dyslexia, and the developmental precursors to the disorder. This research will inform early intervention and remediation efforts and will also assist in the understanding of the normal process of reading acquisition in children.Read moreRead less
Functional Assessment of Head-eye Coordination during Driving. 238 people per 100,000 population were hospitalized and 9 people per 100,000 died as a result of road-transport related injury in Australia in 2002. We will address this issue by assessing the head eye coordination strategies for young drivers, for proficient drivers and for aged drivers to determine those behaviors and strategies that are associated with various levels of performance. This insight could be affectively communicated t ....Functional Assessment of Head-eye Coordination during Driving. 238 people per 100,000 population were hospitalized and 9 people per 100,000 died as a result of road-transport related injury in Australia in 2002. We will address this issue by assessing the head eye coordination strategies for young drivers, for proficient drivers and for aged drivers to determine those behaviors and strategies that are associated with various levels of performance. This insight could be affectively communicated to others and would provide the basis for educational material and methods that would improve operator skill, safety, and performance. These individual improvements would provide overall benefits such as improved transport efficiency, reduced accident rates, saved lives and a reduction in related social costs.Read moreRead less
Sensory Coding Mechanisms in Rat Somatosensory System; A Combined Behavioural and Electrophysiological Approach. This inter-disciplinary project spans behavioural sciences, neurophysiology and computational neuroscience. It investigates fundamental questions such as how different aspects of stimuli are presented in sensory areas of the brain and how the animal interprets the neuronal activity in such areas to generate the relevant behaviour. A major problem with making prosthetic sensory devices ....Sensory Coding Mechanisms in Rat Somatosensory System; A Combined Behavioural and Electrophysiological Approach. This inter-disciplinary project spans behavioural sciences, neurophysiology and computational neuroscience. It investigates fundamental questions such as how different aspects of stimuli are presented in sensory areas of the brain and how the animal interprets the neuronal activity in such areas to generate the relevant behaviour. A major problem with making prosthetic sensory devices is the way by which these devices can communicate with the brain. Research into the coding of different features of simple stimuli will provide basic knowledge which can be implemented in prosthetic sensory devices. Read moreRead less
The roles of spectral cues and auditory plasticity in auditory localisation, speech segregation and speech intelligibility. Our recent work shows that high frequency energy in speech is important for the localisation of speech and may also aid in improving speech intelligibility in noisy environments. The work proposed here will systematically explore this somewhat surprising new finding and the results will be incorporated into a predictive model of speech intelligibility under spatial listenin ....The roles of spectral cues and auditory plasticity in auditory localisation, speech segregation and speech intelligibility. Our recent work shows that high frequency energy in speech is important for the localisation of speech and may also aid in improving speech intelligibility in noisy environments. The work proposed here will systematically explore this somewhat surprising new finding and the results will be incorporated into a predictive model of speech intelligibility under spatial listening conditions. This work includes a systematic study of auditory functional plasticity to changes in the spatial cues. Taken together, the outcomes of this work will unlock a range of new approaches to enhancing spatial hearing in multi-channel communication devices and spatial hearing aids.Read moreRead less
Acoustic, spatial and informational cues used to solve the cocktail party problem. Speech is the principal mode of human communication and yet we understand little about how we are able to concentrate on one talker against a noisy background. Significant improvements in supporting listening by the hearing impaired, in teleconferencing systems and computer speech interfaces are dependent on a more advanced understanding of how we solve this cocktail party problem. This research explores the acous ....Acoustic, spatial and informational cues used to solve the cocktail party problem. Speech is the principal mode of human communication and yet we understand little about how we are able to concentrate on one talker against a noisy background. Significant improvements in supporting listening by the hearing impaired, in teleconferencing systems and computer speech interfaces are dependent on a more advanced understanding of how we solve this cocktail party problem. This research explores the acoustic, spatial and informational cues used by the healthy auditory system to achieve this remarkable feat of signal processing. There is significant potential for commercialization of the IP that will arise from this research.Read moreRead less