Autophagy Increases With Age And Obesity To Protect Against Cellular Damage And Age-related Disease
Funder
National Health and Medical Research Council
Funding Amount
$594,687.00
Summary
Waste recycling is a normal process through which cells clear unwanted material to maintain good health. There are some conditions that are associated with impaired waste recycling in cells (such as dementia), which make this process relevant to lifelong health. We have developed a new test that will, for the first time, enable accurate measurement of the recycling process 'in action' in humans, and may identify people who have poor cellular health.
Hybrid Optical-electrical Stimulation For Precise Neural Stimulation
Funder
National Health and Medical Research Council
Funding Amount
$935,579.00
Summary
In world-first research, we have evidence that combining electrical stimulation with optical stimulation significantly and safely improves precision of neural activation for devices such as cochlear and retinal implants. In this proposal we will use gene therapy to make nerves responsive to light in pre-clinical animal models to establish proof of concept that hybrid stimulation will significantly improve outcomes for recipients of cochlear and retinal implants.