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Development of Knowledge Discovery for High Dimensional Biomedical Data. The recent progress in experimental techniques of molecular genetics has made available a wealth of genome data and raised the interest for analysis of DNA sequences. As the human and mouse genome projects are in a phase of systematic sequencing, computational tools based on concepts used in science fields have recently played a prominent role. Significant contributions to this project will increasingly depend upon original ....Development of Knowledge Discovery for High Dimensional Biomedical Data. The recent progress in experimental techniques of molecular genetics has made available a wealth of genome data and raised the interest for analysis of DNA sequences. As the human and mouse genome projects are in a phase of systematic sequencing, computational tools based on concepts used in science fields have recently played a prominent role. Significant contributions to this project will increasingly depend upon original application and development of algorithms for the analysis of genomic data, and of the computational systems that support them. These challenges have fostered major progress in computer science, leading to collaborative research of global significance.Read moreRead less
Male germ line transgenesis and siRNA technology for manipulating genes in domestic species. Professor Shemesh has successfully developed male germ line transgenesis in species such as bovine and chicken. This technology allows genes to be manipulated via sperm in a wide range of animals besides mice, avoiding the need for a female in vitro fertilization regimen. He is curently applying interference RNA (siRNA) transgenically to manipulate genes in vivo. Together these two technologies offer imm ....Male germ line transgenesis and siRNA technology for manipulating genes in domestic species. Professor Shemesh has successfully developed male germ line transgenesis in species such as bovine and chicken. This technology allows genes to be manipulated via sperm in a wide range of animals besides mice, avoiding the need for a female in vitro fertilization regimen. He is curently applying interference RNA (siRNA) transgenically to manipulate genes in vivo. Together these two technologies offer immense possibilities to manipulate a wide range of species for economic, biotechnological or medical research purposes. Professor Shemesh wishes to come to Adelaide to establish these technologies there as parts of ongoing research projects, related to the physiology of the ovarian hormone relaxin in aging research.Read moreRead less
User-Driven Composition of Web Services. Web service composition technology promises to revolutionise the way in which organisations interact over the Web. However existing environments for the composition of Web services are too complex to use and are usually intended for experienced application developers as they rely either on scripting languages, or on a process-modelling notations intended to be used by IT experts. However, the need for customised composition of Web services is likely to em ....User-Driven Composition of Web Services. Web service composition technology promises to revolutionise the way in which organisations interact over the Web. However existing environments for the composition of Web services are too complex to use and are usually intended for experienced application developers as they rely either on scripting languages, or on a process-modelling notations intended to be used by IT experts. However, the need for customised composition of Web services is likely to emanate from non IT-experts.
The project aims at designing, implementing, and evaluating an environment for the specification and execution of composite Web services by non-expert.Read moreRead less
Privacy-preserving Web Services Composition. Web services composition is emerging as a promising technology for the
effective automation of business-to-business collaborations. It allows
organizations to form alliances by connecting their applications and systems, in order to offer ``one-stops shops'' for their customers. However, several important issues (e.g., security and privacy) need to be properly addressed before Web services technology meets the requirements of critical applications s ....Privacy-preserving Web Services Composition. Web services composition is emerging as a promising technology for the
effective automation of business-to-business collaborations. It allows
organizations to form alliances by connecting their applications and systems, in order to offer ``one-stops shops'' for their customers. However, several important issues (e.g., security and privacy) need to be properly addressed before Web services technology meets the requirements of critical applications such as e-goverment. This project aims at providing privacy preserving Web services composition techniques. The anticipated outcome of this project is a service composition framework that provides seamless interoperability between different Web services without violiating citizens and organisations privacy.Read moreRead less
Crafting Authoritarian Politics. Although Russia is nominally a democracy, strong elements of authoritarianism remain dominant. This project examines how Russia has accommodated these authoritarian themes within a representative democracy and, more generally, seeks to shed new light on the process of democratization in postcommunist societies. Russia is the 8th largest country in the world by population and the 11th largest economy based on GDP; it also remains nuclear-armed. Understanding th ....Crafting Authoritarian Politics. Although Russia is nominally a democracy, strong elements of authoritarianism remain dominant. This project examines how Russia has accommodated these authoritarian themes within a representative democracy and, more generally, seeks to shed new light on the process of democratization in postcommunist societies. Russia is the 8th largest country in the world by population and the 11th largest economy based on GDP; it also remains nuclear-armed. Understanding the dynamics of democratization in Russia has implications for political stability across a large section of the world which is currently in transition from authoritarianism to democracy.Read moreRead less
Cooperative Management of Virtual Teams and Enterprises. Thanks to the proliferation of the Internet and web technologies, it is now possible to exploit the power of these technologies to facilitate the cooperation of teams of workers across distances. Such virtual teams and virtual enterprises are expected to overcome many problems associated in the modern service industry spanning continents. Countries (such as Australia) that are located far from the main markets (e,g, Europe and North Americ ....Cooperative Management of Virtual Teams and Enterprises. Thanks to the proliferation of the Internet and web technologies, it is now possible to exploit the power of these technologies to facilitate the cooperation of teams of workers across distances. Such virtual teams and virtual enterprises are expected to overcome many problems associated in the modern service industry spanning continents. Countries (such as Australia) that are located far from the main markets (e,g, Europe and North America) stand to gain substantially from successful deployment of such virtual organisations. Researchers from UNSW and LORIA France have been working together on the development of cooperative management models for virtual enterprises. This application seeks funding for the travel of researchers across these countries to facilitate this research.Read moreRead less
Singular and Analytic Perturbations, Slow and Fast Time Scales in Control Theory and Viability Theory and their Applications. We propose an innovative approach to several important classes of mathematical problems, whose data depend analytically on small perturbation parameters. Time scale problems, and, in particular, the interaction of two types of evolution, slow and fast, arise in many scientific domains (biotechnology, physics, engineering, etc).We expect to develop new techniques for analy ....Singular and Analytic Perturbations, Slow and Fast Time Scales in Control Theory and Viability Theory and their Applications. We propose an innovative approach to several important classes of mathematical problems, whose data depend analytically on small perturbation parameters. Time scale problems, and, in particular, the interaction of two types of evolution, slow and fast, arise in many scientific domains (biotechnology, physics, engineering, etc).We expect to develop new techniques for analysis and asymptotic optimisation of singularly perturbed control systems and Markov decision processes. In particular, we plan to establish links between general nonlinear optimal control problems with time average criteria and linear programming problems in the space of limit occupational measures generated by the underlying control system.Read moreRead less
Anti-ageing role for relaxin in blood vessels. Arteries stiffen with age. This is due to increased arterial smooth muscle tone and alterations in the extracellular matrix. In a sense, the artery undergoes ?fibrosis? with aging. In light of the anti-fibrotic attributes of the peptide hormone relaxin observed in other tissues, this collaborative project will investigate the potential role for relaxin in opposing arterial ?fibrosis? associated with aging. We will test the hypothesis that a reductio ....Anti-ageing role for relaxin in blood vessels. Arteries stiffen with age. This is due to increased arterial smooth muscle tone and alterations in the extracellular matrix. In a sense, the artery undergoes ?fibrosis? with aging. In light of the anti-fibrotic attributes of the peptide hormone relaxin observed in other tissues, this collaborative project will investigate the potential role for relaxin in opposing arterial ?fibrosis? associated with aging. We will test the hypothesis that a reduction in arterial relaxin expression in older animals is a major cause of arterial stiffening. Further studies will investigate the mechanisms by which relaxin administration can alleviate this phenomenon.Read moreRead less
Automated Interaction Technologies for Mobile Hand-held Devices. This project is concerned with developing intelligent technologies that support human interaction through handheld devices, connected to wireless digital networks. Intelligent software assistants running on these devices will interact with one another in order to coordinate the activities of multiple users. Such automated coordination may facilitate scheduling of meetings, collaboration among different members of a team, and negoti ....Automated Interaction Technologies for Mobile Hand-held Devices. This project is concerned with developing intelligent technologies that support human interaction through handheld devices, connected to wireless digital networks. Intelligent software assistants running on these devices will interact with one another in order to coordinate the activities of multiple users. Such automated coordination may facilitate scheduling of meetings, collaboration among different members of a team, and negotiating conflicts that may arise between the activities of different connected users. This will enable context-dependent task support and coordination of workers involved in industrial applications involving mobility and dynamism.Read moreRead less
Environmental quality and health in the elderly; The Australian situation and international comparison. The elderly are a vulnerable population group that should receive particular attention in health policy. They are a group of considerable and growing size that contributes disproportionately to total health burden. Although residential environment is likely to influence health and well-being among the elderly, the evidence-base for appropriate policy and practice is lacking. Improved understa ....Environmental quality and health in the elderly; The Australian situation and international comparison. The elderly are a vulnerable population group that should receive particular attention in health policy. They are a group of considerable and growing size that contributes disproportionately to total health burden. Although residential environment is likely to influence health and well-being among the elderly, the evidence-base for appropriate policy and practice is lacking. Improved understanding of the role of relevant environmental factors could lead to substantially reduced morbidity and mortality (and associated costs) for the key outcomes: falls, and cardiovascular and respiratory disease. Results will contribute to the international evidence-base in this increasingly critical area of research, policy, and practice. Read moreRead less