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The identification, prevention and management of chronic disease risk factors and understanding impact on clinical outcomes is fundamental to improving health and well-being. The program of work encapsulated in this application utilises a number of research methods to advance our understanding and provide new directions for cardiovascular disease prevention and management.
Improving The Prevention, Treatment And Management Of Cardiovascular & Chronic Disease In The Community
Funder
National Health and Medical Research Council
Funding Amount
$774,540.00
Summary
The identification, prevention and management of cardiovascular and chronic disease risk factors and understanding impact on clinical outcomes is fundamental to improving health and well-being. The program of work encapsulated in this application utilises modern epidemiological research methods involving large scale clinical trials, registries and epidemiological modelling to advance our understanding and provide new directions for cardiovascular disease prevention and management.
Addressing Evidence-practice Gaps In Chronic Disease Prevention And Control
Funder
National Health and Medical Research Council
Funding Amount
$709,931.00
Summary
Cardiovascular diseases are the leading causes of premature death and disability worldwide. Effective treatments for prevention and control of these conditions are available however their use remains far from optimal, in Australia and globally. My current and proposed research will develop and evaluate highly innovative solutions to reduce large evidence-practice gaps in healthcare delivery. These include task shifting to non-physician health workers and novel approaches to drug delivery.
My research focus is the physical and mental health of Australian women at midlife. Over the next 5 years I will address the management of severe menopausal symptoms, midlife depression and the neglected health needs of women during and after cancer treatment, organ transplant and severe persistent mental illness. I will also investigate novel treatment approaches for menopausal symptoms. I will work closely with relevant professional and community groups in planning, implementation and translat ....My research focus is the physical and mental health of Australian women at midlife. Over the next 5 years I will address the management of severe menopausal symptoms, midlife depression and the neglected health needs of women during and after cancer treatment, organ transplant and severe persistent mental illness. I will also investigate novel treatment approaches for menopausal symptoms. I will work closely with relevant professional and community groups in planning, implementation and translation to ensure my research addresses their needs.Read moreRead less
Innovative Health Programs To Reduce Inequality In Heart Disease
Funder
National Health and Medical Research Council
Funding Amount
$876,005.00
Summary
As part of his Senior NHMRC Fellowship, Prof Simon Stewart, a world-renowned health services researcher, will lead an internationally linked team of researchers from a broad range of health disciplines to undertake a program of research designed to improve the lives of those most vulnerable to heart disease and poor health outcomes. His program of research will focus on Indigenous Australians, patients with complex forms of heart disease and urban African communities in economic transition.
Increasing Value, Reducing Waste From Incomplete Or Unusable Reports Of Medical Research
Funder
National Health and Medical Research Council
Funding Amount
$788,486.00
Summary
We estimated that the avoidable waste in research - from design flaws, non-publication, and inadequate reporting - results in over $85 Billion annual loss. I will research innovations to reduce this waste. My focus is particularly on non-drug interventions - exercises, dietary changes, self-monitoring, e-health applications – which are often effective but more difficult to use in clinical practice, and being compiled in my recently founded Handbook of Non-Drug Interventions (see RACGP website).
Professor John Simes is director of the NHMRC Clinical Trials Centre and has a background in oncology, biostatistics and epidemiology. He leads a program of clinical trials, mainly in oncology, cardiovascular disease and neonatology, with associated research into trials methods, biostatistical analysis, patient preferences, individualising treatment, decision analysis and the application of trial evidence to clinical decision making.
Defining Optimal Strategies For Sustained Control Of Infectious Diseases
Funder
National Health and Medical Research Council
Funding Amount
$763,845.00
Summary
My work helps us understand how infections spread between people, to work out the most effective use of vaccines and other protective measures. This fellowship will support research into the ways large family size, poor health care access, social connections and the environment increase infection risk in settings of poverty. We will find better ways to prevent infectious diseases in the populations worst affected, including Indigenous Australians and people living in low-income countries.
New Technologies To Reduce The Population Burden Of Sexually Transmitted Infections
Funder
National Health and Medical Research Council
Funding Amount
$772,605.00
Summary
I propose a five year program of public health research on the evaluation of innovative technologies to prevent sexually transmitted infections (STIs) and their adverse consequences in populations at highest risk; Aboriginal and Torres Strait Islander people, youth, men who have sex with men and people in high STI-burden resource-limited countries. My research over the next five years will lead to substantial improvements in the health of people at greatest risk of STIs.
Enhanced Prevention And Control Of Sexually Transmitted Infections
Funder
National Health and Medical Research Council
Funding Amount
$782,370.00
Summary
The entire developed world is witnessing dramatic increases in bacterial sexually transmitted infections (STIs), the likes of which have not been seen since prior to the emergence of the HIV epidemic in the 1980s. My vision is to reduce the burden of STIs by identifying innovative, cost-effective approaches to STI prevention and management that are acceptable to the populations affected (including healthcare workers and people are risk of STIs) and able to be implemented on a broad scale.