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METHODS - A Randomised Controlled Trial Of METhotrexate To Treat Hand Osteoarthritis With Synovitis
Funder
National Health and Medical Research Council
Funding Amount
$770,014.00
Summary
Hand osteoarthritis (OA) is common, but has no treatment. Almost 50% of people with hand OA will have joint swelling (synovitis). The hand joint of people with synovitis are 3.5 times more likely to experience joint destruction within as little as 2 years. Drugs used to treat synovitis may reduce pain and joint destruction. We propose that treating patients with symptomatic hand OA and synovitis with the anti-synovitis drug, methotrexate, will be a major medical advance.