Some infections can start inflammation that, while controlling the infection, can also attack the body tissues of genetically susceptible people. This inflammation can initiate long term problems including arthritis, diabetes and cancer. Our research program seeks to understand who is genetically at risk of this sort of problem and why, and thus to develop new means to prevent and treat the chronic diseases that are initiated in this way.
This Program Grant brings together a world-leading team of experts to elucidate mechanisms that protect most people from infection by making antibodies, and their failure caused by genes or infections like influenza or HIV. The team will determine mechanisms that protect most people from making antibodies against normal parts of our body, whose failure causes numerous autoimmune diseases including rheumatoid arthritis. The team will develop ways to engineer better antibodies.
The Australian MRI-Linac Program: Transforming The Science And Clinical Practice Of Cancer Radiotherapy
Funder
National Health and Medical Research Council
Funding Amount
$7,001,475.00
Summary
Radiotherapy is indicated for 48% of cancer patients. The Australian MRI-Linac Program will change the science and clinical practice of radiotherapy by explicitly targeting the dynamic anatomy and physiology of cancer, increasing cancer control and decreasing treatment side effects. Successful completion of this program will have a direct impact on the treatment and lives of Australian cancer patients in the foreseeable future.