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Exploring The Role Of Glycogen Structure In Type 2 Diabetes.
Funder
National Health and Medical Research Council
Funding Amount
$367,126.00
Summary
The incidence of type 2 diabetes, a disease hallmarked by poor blood glucose control, is rapidly increasing in Australia. This project will investigate the role of liver-glycogen, our blood glucose buffer, in the pathology type 2 diabetes, with particular focus on the glycogen’s structure. By determining the importance of glycogen structure on its properties and how this affects diabetic’s blood glucose levels will potentially result in new drug target for the treatment of type 2 diabetes.
Glycaemia And Cardiovascular Disease Outcomes In Patients With Diabetes And CKD: Methodology, Relationship And
Funder
National Health and Medical Research Council
Funding Amount
$143,661.00
Summary
Diabetes is increasing and now the primary cause of chronic kidney disease (CKD). At present the care of people with diabetes and CKD aims to achieve normal blood glucose levels in the safest possible way in order to prevent acute and chronic complications and improve outcomes and quality of life. In this project we will examine the best means by which to measure, monitor and treat blood glucose levels in such people and explore the effect of intensive blood glucose control.
Patients With Obstructive Sleep Apnoea And Motor Control
Funder
National Health and Medical Research Council
Funding Amount
$302,798.00
Summary
Obstructive Sleep Apnoea is a major health concern, affecting at least 4% of the population, associated with obesity, and aging. The symptoms of sleep apnoea are definitively associated with cardiovascular complications. I am focused on understanding how sleep apnoea patients are remodelled with the rewiring of connections between the brain and muscles. Using neurophysiological techniques, this project will study how the anatomy and functional connections of circuits change with sleep apnoea.
Neural Control Of Human Respiratory Muscles In Health And Disease
Funder
National Health and Medical Research Council
Funding Amount
$450,132.00
Summary
This research examines how human inspiratory muscles that ‘pump’ air into the lungs are controlled in health and disease. We will study the interaction between automatic and voluntary control of breathing, about which very little is known. The control of breathing in patients who breathe against an inspiratory load (eg. asthma) and mechanically ventilated patients will be a focus of this research. Outcomes include better understanding of the control of breathing and improved patient care.
Harnessing New Media To Translate Prevention Research Evidence In To Practice And Policy
Funder
National Health and Medical Research Council
Funding Amount
$321,414.00
Summary
This project is focused on two key priority areas of prevention research: tobacco control and obesity. The main aim of this project is to strengthen the knowledge base and evidence-based application of new media for preventive health initiatives.The research will provide missing insight into how to use new media more effectively to translate prevention research findings in to policy and programs.