Steroid-Reducing Options For ReLapsING PMR (STERLING-PMR): A Pragmatic, Randomised Trial To Compare The Clinical And Cost-effectiveness Of Adding Immunosuppression To Steroid-tapering Treatment For Patients With Relapsing PMR, Versus Steroid-tapering
Funder
National Health and Medical Research Council
Funding Amount
$823,722.00
Summary
Polymyalgia rheumatica (PMR) is a common inflammatory disease of older people, treated with prednisolone (steroid tablet). About 50% will relapse and often suffer from steroid side effects (eg diabetes, bone fracture). This study will determine whether an extra treatment can reduce prednisolone use in people with relapsing PMR; and improve quality of life. The study will include participants in UK and Australia and provide a unique opportunity for further research in this under-researched area.