Glaucoma is a progressive, poorly understood blinding disease with limited treatment options. It is characterised by the death of the nerve cells in the eye whose fibres form the optic nerve. Results obtained in the current proposal will lead to a better understanding of key features of the early stages of the disease and, additionally, will explore the potential of a novel therapeutic approach based on regeneration of damaged nerve fibres within the optic nerve.
AGE-RELATED IMPAIRMENT OF AUTOREGULATION: A MODIFIABLE RISK FACTOR FOR GLAUCOMA
Funder
National Health and Medical Research Council
Funding Amount
$414,982.00
Summary
The prevalence and incidence of glaucoma increase dramatically with age. An impaired capacity to buffer against physiological pressure fluctuations in the eye with aging may play a key role in the development of glaucoma. This project will use non-invasive imaging to determine if impaired autoregulation increases the risk of developing glaucoma. It will determine if this age-related decline in autoregulation can be restored and in this way provide protection against glaucoma.