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The effect of mitochondrial and nuclear-cytoplasmic variation on longevity, metabolism and stress resistance in Drosophila. Much research points to a major role of free radical damage in aging, thus the belief that antioxidants might be beneficial in delaying aging. Free radicals are mostly formed in the subcellular organelles which consume oxygen and produce energy, and this may be the major site of age-related damage. This project seeks to understand the degree to which variation among these ....The effect of mitochondrial and nuclear-cytoplasmic variation on longevity, metabolism and stress resistance in Drosophila. Much research points to a major role of free radical damage in aging, thus the belief that antioxidants might be beneficial in delaying aging. Free radicals are mostly formed in the subcellular organelles which consume oxygen and produce energy, and this may be the major site of age-related damage. This project seeks to understand the degree to which variation among these subcellular organelles affect free radical damage and aging, using the fruitfly Drosophila melanogaster as a model organism.Read moreRead less
From Suspician to Intervention : Improving responsiveness to abuse of the elderly in acute and sub-acute health care. Early identification of risk and an integrated multidisciplinary response across the health service would be effective in responding to the multiple and complex behavioural and social issues which contribute to aged abuse as it presents in emergency, acute and sub-acute care, but are currently often ignored in health services and the literature. We propose that effective use of ....From Suspician to Intervention : Improving responsiveness to abuse of the elderly in acute and sub-acute health care. Early identification of risk and an integrated multidisciplinary response across the health service would be effective in responding to the multiple and complex behavioural and social issues which contribute to aged abuse as it presents in emergency, acute and sub-acute care, but are currently often ignored in health services and the literature. We propose that effective use of this "window of opportunity in health care" could extend the level of community response to this vulnerable group of people. Read moreRead less
Community Engagement for Productive Ageing: Models to support rural healthy ageing through the maintenance of community involvement and contribution. Governments at all levels are concerned about the looming social and economic challenges flowing from an ageing population. At present, ageing services are largely focussed on caring for the frail dependent aged. Yet, ultimately, the key to meeting the ageing challenge will lie in how successful we are in supporting our healthy independent aged to ....Community Engagement for Productive Ageing: Models to support rural healthy ageing through the maintenance of community involvement and contribution. Governments at all levels are concerned about the looming social and economic challenges flowing from an ageing population. At present, ageing services are largely focussed on caring for the frail dependent aged. Yet, ultimately, the key to meeting the ageing challenge will lie in how successful we are in supporting our healthy independent aged to stay contributing and productive members of their community. By developing evidence-based interventions that focus on preventing social disengagement before it occurs, the project provides a cost effective approach to ensuring that Australia's rapidly growing aged cohort remain social assets and do not become social burdens.Read moreRead less
Connecting younger second language learners and older bilinguals: Intergenerational, intercultural encounters and second language development. This project brings together upper secondary school learners of Chinese, German or Spanish and older speakers of the language, promoting mutually beneficial inter-cultural, intergenerational encounters. Valuable community language resources will be tapped to motivate and enhance the second language learning for the social, cultural and economic benefits. ....Connecting younger second language learners and older bilinguals: Intergenerational, intercultural encounters and second language development. This project brings together upper secondary school learners of Chinese, German or Spanish and older speakers of the language, promoting mutually beneficial inter-cultural, intergenerational encounters. Valuable community language resources will be tapped to motivate and enhance the second language learning for the social, cultural and economic benefits. The model promises to make senior secondary second language learning more effective. Australia's social fabric will be enhanced by interactions between cultures and between generations. The project addresses two important goals of the research Priority II --- It is strengthening the Australian social and economic fabric and ageing well, ageing productively.Read moreRead less
Gene-environment Interaction In Healthy Brain Ageing And Age Related Neurodegeneration
Funder
National Health and Medical Research Council
Funding Amount
$2,162,805.00
Summary
Healthy ageing is characterised by low level of disability, high cognitive and functional capacity, and an active engagement in life. The most important ingredient of healthy ageing is a healthy brain, bereft of age-related diseases and dysfunction. Brain ageing and brain diseases are determined by multiple genetic factors that interact with environmental influences. The genes are multiple, the majority of which have a small influence. This study is an attempt to identify some of these genes and ....Healthy ageing is characterised by low level of disability, high cognitive and functional capacity, and an active engagement in life. The most important ingredient of healthy ageing is a healthy brain, bereft of age-related diseases and dysfunction. Brain ageing and brain diseases are determined by multiple genetic factors that interact with environmental influences. The genes are multiple, the majority of which have a small influence. This study is an attempt to identify some of these genes and investigate their interactions with environmental factors. It will use a unique resource, the NHMRC Australian Twin Registry (ATR) to identify elderly twins, and will also include the siblings of these twins so as to increase the ability to identify the important factors. The participants, who are listed on the ATR and recruited from NSW, Queensland and Victoria, will receive detailed neurological, psychiatric and cognitive assessments, and will undergo brain MRI scans. Their blood samples will be used to measure key chemicals that may affect brain ageing and to extract DNA for genetic tests. They will be followed-up every two years thereafter, and changes in their brain structure and cognitive functioning will be examined. Available statistical models will be used to examine gene-environment interactions and specific genes will be explored for their contribution to the additive genetic effects. This study will yield an important resource for national and international collaborations and has the potential to discover new genes.Read moreRead less
Telehealth In Residential Aged Care Facilities: Improving Access To Specialist Care
Funder
National Health and Medical Research Council
Funding Amount
$972,606.00
Summary
People in long term residential care have complex and chronic care issues. The staff may be able to provide more focused care if they have the support of specialists for advice on the care of residents. This project considers the value of a geriatric specialist assessment for all new residents via video conferencing, directly to the residential care facility. This will be supplemented by access to a wide range of other specialists coordinated through a telehealth service model on an "as needs" b ....People in long term residential care have complex and chronic care issues. The staff may be able to provide more focused care if they have the support of specialists for advice on the care of residents. This project considers the value of a geriatric specialist assessment for all new residents via video conferencing, directly to the residential care facility. This will be supplemented by access to a wide range of other specialists coordinated through a telehealth service model on an "as needs" basis.Read moreRead less
Peopling educational policy: realising the new Australian English and mathematics curricula. Implementation of Australian curricula in English and mathematics provides an opportunity for school systems to re-examine practice. This project will identify resources and teacher learning opportunities needed to facilitate implementation of these curricula and use findings to develop interventions identified as likely to optimise implementation.
The Lexicon Project: Analysing pedagogical naming systems from different cultures to reconceptualise classroom practice and advance educational theory. Classrooms remain the principal site of institutionalised learning. Their cultural specificity poses challenges for international comparative research. New approaches are needed. Internationally, our educational theories, research and descriptions of practice are framed in English, which names some aspects of the classroom, but ignores key aspect ....The Lexicon Project: Analysing pedagogical naming systems from different cultures to reconceptualise classroom practice and advance educational theory. Classrooms remain the principal site of institutionalised learning. Their cultural specificity poses challenges for international comparative research. New approaches are needed. Internationally, our educational theories, research and descriptions of practice are framed in English, which names some aspects of the classroom, but ignores key aspects named in other languages. This limits our capacity to access, connect and adapt the wisdom of other cultures. The Lexicon Project will initiate cross-cultural dialogue to identify pedagogical terms from selected Asian and European educational communities and use these as analytical tools to categorise, interrogate and enrich our classroom practice, classroom research, and educational theorising.Read moreRead less
Using mathematics to solve real world problems. This project aims to identify, apply and refine teaching approaches that help secondary students learn mathematical modelling, using mathematics to solve real world problems. The study will investigate the mathematical, cognitive, social and environmental factors that "enable" Year 10/11 students to develop mathematical representations of a real world problem. This project expects to generate theoretical and practical insights into how these enable ....Using mathematics to solve real world problems. This project aims to identify, apply and refine teaching approaches that help secondary students learn mathematical modelling, using mathematics to solve real world problems. The study will investigate the mathematical, cognitive, social and environmental factors that "enable" Year 10/11 students to develop mathematical representations of a real world problem. This project expects to generate theoretical and practical insights into how these enablers promote successful modelling, tasks that support students' development as modellers, and effective teaching approaches that promote student capability and interest in mathematics.Read moreRead less
Investigating the relationship between teacher expectations, student persistence and the learning of mathematics. There is a culture in many classrooms in which teachers are encouraged by students to pose easy tasks. The project will explore what is needed to encourage students to embrace challenges and to persist even when tasks are difficult. The outcome will be enhanced mathematics learning and improved student confidence.