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Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not re ....Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not respond to the current TNF treatments. Improved anti-TNF strategies would provide enhanced health outcomes and welcome relief to many Australians. In addition, the economic benefit of the TNF market is very substantial. Therefore the potential impact of this research is very high both for health care and economical potential.Read moreRead less
CENTRE for INTEGRATIVE LEGUME RESEARCH. Legumes are essential for environmental sustainability and are important for maintaining human health. The Centre combines innovative genomic approaches to investigate the causal phenotypic links required for regulation of legume growth. The unique coexistence of multiple pluripotent meristems in shoots, roots, flowers and nodules permits the discovery of new paradigms governing legume architecture, reproductive differentiation and root-nodule developmen ....CENTRE for INTEGRATIVE LEGUME RESEARCH. Legumes are essential for environmental sustainability and are important for maintaining human health. The Centre combines innovative genomic approaches to investigate the causal phenotypic links required for regulation of legume growth. The unique coexistence of multiple pluripotent meristems in shoots, roots, flowers and nodules permits the discovery of new paradigms governing legume architecture, reproductive differentiation and root-nodule development. New knowledge of the plant growth processes through mechanistic analysis of organ induction provides the tools to optimise the legume's productivity, quality, and environment adaptation.Read moreRead less
Special Research Initiatives - Grant ID: SR0354599
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
An Integrated Intelligent Bio-machines Network. The increasing use of computing, advanced materials, electronic control with biological or human applications has provided the need to strengthen the nexus of these discipline areas. This proposal is expected to identify the critical areas of integration that can be realistically developed into meaningful technologies and products in the short-to-medium term. The significance of this network is to enhance the science and technology required for sy ....An Integrated Intelligent Bio-machines Network. The increasing use of computing, advanced materials, electronic control with biological or human applications has provided the need to strengthen the nexus of these discipline areas. This proposal is expected to identify the critical areas of integration that can be realistically developed into meaningful technologies and products in the short-to-medium term. The significance of this network is to enhance the science and technology required for systems and products such as bionic eyes, legs, muscles and larynxes. These products and systems characterize the essence of this network: The integration of hardware and software with wetware (Humans).Read moreRead less