The genetics of resistance to devil facial tumour disease. Tasmanian devils are on the brink of extinction due to a new contagious cancer: Devil Facial Tumour Disease (DFTD). The aim of this project is to determine the genetic nature of DFTD resistance in order to directly contribute to the conservation management of this iconic and ecologically important species. This research will generate fundamental information about genetic diversity in Tasmanian devils and establish the feasibility of bree ....The genetics of resistance to devil facial tumour disease. Tasmanian devils are on the brink of extinction due to a new contagious cancer: Devil Facial Tumour Disease (DFTD). The aim of this project is to determine the genetic nature of DFTD resistance in order to directly contribute to the conservation management of this iconic and ecologically important species. This research will generate fundamental information about genetic diversity in Tasmanian devils and establish the feasibility of breeding resistant animals for release into the wild. Read moreRead less
Complex trait analyses based on genome-wide approaches. This project aims to develop whole genome approaches that can improve the estimation and prediction power by using information from the dynamic genetic architecture of complex traits (i.e. the changes of genetic characteristics and effects when varying effective population size and genetic backgrounds). The project intends to deliver advanced statistical models, efficient algorithms and design by combining data from close relatives, populat ....Complex trait analyses based on genome-wide approaches. This project aims to develop whole genome approaches that can improve the estimation and prediction power by using information from the dynamic genetic architecture of complex traits (i.e. the changes of genetic characteristics and effects when varying effective population size and genetic backgrounds). The project intends to deliver advanced statistical models, efficient algorithms and design by combining data from close relatives, population samples or from different populations (e.g. multi-ethnicities or multi-breeds). The expected outcome is to better understand the dynamic architecture of complex traits and develop methods with improved power, precision and accuracy in genomic analyses.Read moreRead less