Enhancing Grain Yield Potential and Quality of Lupin. Sustainability of wheat production in Western Australia depends on the continued use of legumes, specifically lupins, in farming systems. The low returns to growers for lupins has jeopardised these sustainable systems. This project aims to gather new information to develop novel genetic strategies to increase yield potential and modify seed composition in lupins, enhancing their commercial worth.
Brassica genome organisation and evolution: unlocking the potential of using genome-specific repetitive elements for crop improvement. Introgression of chromosome segments from related Brassica species provides an opportunity to develop locally adapted varieties with improved agronomic and quality traits. There is a need to understand Brassica genome organisation and how this information can be used for enhancing the efficiency of cultivar development. Dispersed and tandem repetitive DNA sequen ....Brassica genome organisation and evolution: unlocking the potential of using genome-specific repetitive elements for crop improvement. Introgression of chromosome segments from related Brassica species provides an opportunity to develop locally adapted varieties with improved agronomic and quality traits. There is a need to understand Brassica genome organisation and how this information can be used for enhancing the efficiency of cultivar development. Dispersed and tandem repetitive DNA sequences provide valuable information on the organisation and evolution of plant chromosomes. Methods for monitoring chromosome segment transfer across Brassica species will be developed based on detecting and quantifying genome-specific repetitive DNA sequences. Australian Brassica improvement programs could benefit from this research by adopting methods to detect chromosome segment transfer during interspecific hybridisation.Read moreRead less
Exploiting the Arabidopsis genome sequence as a molecular 'toolbox' for Brassica improvement. Australia's position as a major exporter of canola (Brassica napus) is under threat from genetic improvements in yield and quality being made by our international competitors. We will identify genes from Arabidopsis (the 'tool-box') that will be used to increase the speed of selection of new canola varieties with improved oleic acid content, disease resistance, and agronomic traits such as early flower ....Exploiting the Arabidopsis genome sequence as a molecular 'toolbox' for Brassica improvement. Australia's position as a major exporter of canola (Brassica napus) is under threat from genetic improvements in yield and quality being made by our international competitors. We will identify genes from Arabidopsis (the 'tool-box') that will be used to increase the speed of selection of new canola varieties with improved oleic acid content, disease resistance, and agronomic traits such as early flowering and cold tolerance. Genome similarity between Arabidopsis and canola will be exploited to map specific genes from Arabidopsis directly into canola. Based on this knowledge, we will develop gene-specific molecular markers for rapid selection of Australian-adapted canola varieties.Read moreRead less
Fast tracking pea weevil resistance into field pea cultivars through interspecific hybridisation. Field pea is a high value export product of Australia and increased adoption will lead to greater sustainability of agriculture, improved farm income and value adding opportunities (eg. food industry) in regional Australia. Novel breeding tools used within this project will accelerate the development of pea weevil resistant field peas that are less dependent on the application of pesticides than cur ....Fast tracking pea weevil resistance into field pea cultivars through interspecific hybridisation. Field pea is a high value export product of Australia and increased adoption will lead to greater sustainability of agriculture, improved farm income and value adding opportunities (eg. food industry) in regional Australia. Novel breeding tools used within this project will accelerate the development of pea weevil resistant field peas that are less dependent on the application of pesticides than current varieties. Their availability will encourage further uptake of field pea into Australian cropping systems, contributing to environmentally sustainable farming systems by improving soil nitrogen levels and reducing the environmental effect of pesticides.Read moreRead less
Genetic variation in narrow leafed lupin (NLL) accessions and breeding programs. The centre of origin of a crop plant is expected to have the greatest extant genetic variation of wild relatives. Development of modern cultivars may be accompanied by a severe genetic bottleneck, whereby subsequent breeding efforts are hampered by lack of significant genetic variation within domesticated breeding material. This proposal will research the extent to which the available genetic variation in wild acces ....Genetic variation in narrow leafed lupin (NLL) accessions and breeding programs. The centre of origin of a crop plant is expected to have the greatest extant genetic variation of wild relatives. Development of modern cultivars may be accompanied by a severe genetic bottleneck, whereby subsequent breeding efforts are hampered by lack of significant genetic variation within domesticated breeding material. This proposal will research the extent to which the available genetic variation in wild accessions of the recently developed crop Lupinus angustifolius has been utilised in breeding programs around the world. Results will be applied to broaden the gene pool and improve adaptation of new cultivars in the National Lupin Improvement Program.Read moreRead less
Evaluating The Genetic Contribution To Rheumatic Heart Disease Pathogenesis In Australian Aboriginal And Torres Strait Islander Communities
Funder
National Health and Medical Research Council
Funding Amount
$1,782,074.00
Summary
Rheumatic heart disease is highly prevalent in Aboriginal people in Australia and leads to early cardiac disease. Despite decades of research, the underlying genetic mechanisms for why it occurs are not well understood. We are conducting a genetic study to better understand why some people are susceptible to RHD and others are not. The study will involve substantial Aboriginal leadership and consultation and will be a model for the conduct of genetic studies in Aboriginal populations.
Physiological and genetic mechanisms underlying tolerance of bread wheat to ion toxicities. Ion toxicities associated with acidic or alkaline soils and waterlogging cost about $190 million per year in lost yield in Western Australia alone. Soil ameliorants and agricultural measures to deal with these constraints are non-existent (B toxicity in alkaline sodic subsoils), non-effective (liming of acidic subsoils), expensive (drainage for waterlogged soils) or a combination of the above. This projec ....Physiological and genetic mechanisms underlying tolerance of bread wheat to ion toxicities. Ion toxicities associated with acidic or alkaline soils and waterlogging cost about $190 million per year in lost yield in Western Australia alone. Soil ameliorants and agricultural measures to deal with these constraints are non-existent (B toxicity in alkaline sodic subsoils), non-effective (liming of acidic subsoils), expensive (drainage for waterlogged soils) or a combination of the above. This project will characterise wheat genotypes for tolerance to ion toxicities and will lay the groundwork for deliberate breeding effort toward pyramiding tolerance to ion toxicities in elite germplasm.Read moreRead less
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
Physiological and molecular characterisation of salinity tolerance in chickpea. Chickpea is a grain legume often grown in rotation with cereal crops to enhance profitability and environmental sustainability of broadacre cropping systems in Australia, and elsewhere. Chickpea is sensitive to salinity, and thus can not be grown on soils affected even by mild salinity. Limited grain legume options currently exist for these soils. This project will improve salt tolerance in chickpea and thus allow it ....Physiological and molecular characterisation of salinity tolerance in chickpea. Chickpea is a grain legume often grown in rotation with cereal crops to enhance profitability and environmental sustainability of broadacre cropping systems in Australia, and elsewhere. Chickpea is sensitive to salinity, and thus can not be grown on soils affected even by mild salinity. Limited grain legume options currently exist for these soils. This project will improve salt tolerance in chickpea and thus allow it to be grown in areas too saline for current cultivars. The research contributes to the National Research Priority of 'An Environmentally Sustainable Australia', as new cultivars of chickpea with improved salt tolerance will enhance the profitability and sustainability of rotational cropping systems in Australia.Read moreRead less
Gene identification and genetic marker analysis of herbicide resistance in Lolium rigidum. Herbicide resistance threatens the vibrant, export-focused Australian cropping industry and environmental sustainability. The Australian herbicide resistance problem is far greater than elsewhere in the world. Herbicide resistance must be avoided, managed and reversed to ensure profitable agriculture and an environmentally sustainable landscape. This research will contribute to the national wealth through ....Gene identification and genetic marker analysis of herbicide resistance in Lolium rigidum. Herbicide resistance threatens the vibrant, export-focused Australian cropping industry and environmental sustainability. The Australian herbicide resistance problem is far greater than elsewhere in the world. Herbicide resistance must be avoided, managed and reversed to ensure profitable agriculture and an environmentally sustainable landscape. This research will contribute to the national wealth through helping ensure the profitability of vital Australian export agricultural industries and the sustainability of the soil/land resource. This proposal will ensure that Australia leads international herbicide resistance research and will enable the capture of intellectual property and commercial opportunities. Read moreRead less