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Erosion processes in soils across scales. This project aims to develop a monitoring tool for predicting the evolution of internal erosion in dams based on innovative electromagnetic observation methods. Internal erosion is an insidious process occurring in the obscurity of the soil’s pore system until its consequences become visible and threaten the stability of the dams. These water retaining structures are vital for the future water and energy supply for our society and their failure can be ca ....Erosion processes in soils across scales. This project aims to develop a monitoring tool for predicting the evolution of internal erosion in dams based on innovative electromagnetic observation methods. Internal erosion is an insidious process occurring in the obscurity of the soil’s pore system until its consequences become visible and threaten the stability of the dams. These water retaining structures are vital for the future water and energy supply for our society and their failure can be catastrophic. By establishing an improved understanding of internal erosion as a sequence of processes on various scales, from the onset of erosion until the failure of the structure, this project will place Australia at the forefront of dam safety assessment.Read moreRead less
Bottom-up multiscale modelling of expansive soils in natural environments . Expansive soils, highly sensitive to the environment, undergo dramatic strength and volume changes. This project aims to advance our understanding of expansive soils under different temperatures, hydraulic conditions, mechanical loads, and aqueous salinities. The project expects to use a combination of multidisciplinary knowledge, multiscale experiments and numerical simulations. The outcomes are a new multiscale model a ....Bottom-up multiscale modelling of expansive soils in natural environments . Expansive soils, highly sensitive to the environment, undergo dramatic strength and volume changes. This project aims to advance our understanding of expansive soils under different temperatures, hydraulic conditions, mechanical loads, and aqueous salinities. The project expects to use a combination of multidisciplinary knowledge, multiscale experiments and numerical simulations. The outcomes are a new multiscale model and advanced analysis/design tool for evaluating the performance of expansive soils under different conditions. The outcomes should provide the efficient way to mitigate the significant damage caused to infrastructure by expansive soils and facilitate the application of expansive soil products in waste disposal systems.Read moreRead less
Designing functional biomaterials with superior cellular interactions. This proposal aims to make a new class of biomaterials that direct important cellular functions such as adhesion, proliferation, and differentiation. This will be achieved by developing materials that leverage a previously unexplored mechanism that was recently identified in my lab: the co-engagement of integrin and syndecan-4 cell receptors. We will use these biomaterials to 1) fabricate 3D printed tissue engineering scaffo ....Designing functional biomaterials with superior cellular interactions. This proposal aims to make a new class of biomaterials that direct important cellular functions such as adhesion, proliferation, and differentiation. This will be achieved by developing materials that leverage a previously unexplored mechanism that was recently identified in my lab: the co-engagement of integrin and syndecan-4 cell receptors. We will use these biomaterials to 1) fabricate 3D printed tissue engineering scaffolds with a superior ability to promote the development of new tissue, and 2) create surfaces that will enable us to answer fundamental scientific questions regarding cell adhesion and cell/material interactions.Read moreRead less
How is the blood cell population size controlled? Macrophage-like cells are an ancient animal blood cell lineage critically important for development, immunity, and homeostasis. This fellowship seeks to reveal the genes and control mechanisms used by animals to achieve an optimally-sized army of these cells - to contain threats for survival upon infection, heal following acute stress exposures, or for development, ongoing maintenance, and repair of wear and tear. By marrying the genetic tractabi ....How is the blood cell population size controlled? Macrophage-like cells are an ancient animal blood cell lineage critically important for development, immunity, and homeostasis. This fellowship seeks to reveal the genes and control mechanisms used by animals to achieve an optimally-sized army of these cells - to contain threats for survival upon infection, heal following acute stress exposures, or for development, ongoing maintenance, and repair of wear and tear. By marrying the genetic tractability of the model organism Drosophila and its simple, yet conserved blood cell system, this project will yield new insights into the mechanisms that govern the animal blood cell population. This will benefit our fundamental understanding of how animals maximise their health throughout life.Read moreRead less
Advanced hydrodynamics for next generation of offshore infrastructure. This project aims to develop rigorous and precise prediction models for next generation offshore infrastructure, by capturing nonlinear wave-structure interaction. This project expects to generate new knowledge in offshore hydrodynamics (a branch of fluid mechanics) applicable to Ocean Engineering, using cutting-edge numerical technology, state-of-the-art physical modelling, and unique full-scale field data. The expected outc ....Advanced hydrodynamics for next generation of offshore infrastructure. This project aims to develop rigorous and precise prediction models for next generation offshore infrastructure, by capturing nonlinear wave-structure interaction. This project expects to generate new knowledge in offshore hydrodynamics (a branch of fluid mechanics) applicable to Ocean Engineering, using cutting-edge numerical technology, state-of-the-art physical modelling, and unique full-scale field data. The expected outcomes include enhanced capacity to estimate hydrodynamic response and advanced design tools for floating wind, floating solar and offshore aquaculture. This will provide significant benefit by enabling cost-efficient and viable designs, thereby accelerating the development of offshore renewable energy.Read moreRead less
Next-generation computational models to understand human joints . This project aims to investigate human joint systems through combining state-of-the-art imaging and high-fidelity biomechanical models. The methods developed in this project are expected to generate new ways of studying the dynamic response of musculoskeletal tissues to activity, including how musculoskeletal physiology can adapt to biomechanical stimuli. Expected outcomes include establishing a non-invasive method for characteris ....Next-generation computational models to understand human joints . This project aims to investigate human joint systems through combining state-of-the-art imaging and high-fidelity biomechanical models. The methods developed in this project are expected to generate new ways of studying the dynamic response of musculoskeletal tissues to activity, including how musculoskeletal physiology can adapt to biomechanical stimuli. Expected outcomes include establishing a non-invasive method for characterising whole joint systems. This project will provide significant knowledge gain on the biomechanical regulation of human joints across form, function, dynamics and loading which may help across many facets of society to guide physical activity choices.Read moreRead less
Anchoring the next generation of offshore floating infrastructure. This project aims to advance the fundamental scientific understanding of embedded anchor behaviour and to develop engineering solutions to secure the next generation of floating platforms, wind turbines and submerged tunnels. This is significant because limited understanding of anchors under long-term sustained and cyclic loading, and in how wave-chain-anchor systems behave, is hindering confident deployment in deep water and har ....Anchoring the next generation of offshore floating infrastructure. This project aims to advance the fundamental scientific understanding of embedded anchor behaviour and to develop engineering solutions to secure the next generation of floating platforms, wind turbines and submerged tunnels. This is significant because limited understanding of anchors under long-term sustained and cyclic loading, and in how wave-chain-anchor systems behave, is hindering confident deployment in deep water and harsh conditions. This project will address this challenge by combining precise observations from sophisticated physical and numerical experiments into an analysis framework that integrates system response. Outcomes will include numerical software, analytical tools and design charts for engineers to use in design.Read moreRead less
Resolving the impact of pressure on hot and low-oxygen combustion. Despite the important role of renewable energy sources, combustion will remain essential for transportation into the foreseeable future. This project aims to investigate flames burning in a hot and low-oxygen environment. The objective is to better understand how these conditions could be applied to gas turbines. This project expects to generate new knowledge to enable a reduction in emissions, improvement in efficiency and incre ....Resolving the impact of pressure on hot and low-oxygen combustion. Despite the important role of renewable energy sources, combustion will remain essential for transportation into the foreseeable future. This project aims to investigate flames burning in a hot and low-oxygen environment. The objective is to better understand how these conditions could be applied to gas turbines. This project expects to generate new knowledge to enable a reduction in emissions, improvement in efficiency and increase in power output. Expected outcomes of this project include improved understanding of the governing physics to enable development of design tools for next-generation engines. This should provide significant benefits, such as reduced reliance on fossil fuels and a critical reduction in greenhouse gas emissions.Read moreRead less
Innovative Data Driven Techniques for Structural Condition Monitoring . Safe and sustainable infrastructure involves the development and application of structural monitoring and assessment techniques for condition evaluation. This project develops an innovative structure condition monitoring approach based on the emerging digital technologies on image processing, data analytics and machine learning techniques, for better infrastructure asset management under operational environment. Expected out ....Innovative Data Driven Techniques for Structural Condition Monitoring . Safe and sustainable infrastructure involves the development and application of structural monitoring and assessment techniques for condition evaluation. This project develops an innovative structure condition monitoring approach based on the emerging digital technologies on image processing, data analytics and machine learning techniques, for better infrastructure asset management under operational environment. Expected outcomes of this project enhance the capacity to conduct the operational monitoring and data interpretation to deliver the best life cycle performance of infrastructure. This project should provide significant benefits to Australia in infrastructure asset management by reducing the interruption of infrastructure operations.Read moreRead less
Linking microstructural evolutions across the scales of granular failure. This project expects to transform the understanding of granular materials and their behaviour by establishing explicit links between the macroscopic responses of the materials and their evolving microstructural properties. This should lead to revolutionary constitutive models for granular materials that possess true mechanisms of evolving grain-scale structures. The proliferation of these new models should allow developmen ....Linking microstructural evolutions across the scales of granular failure. This project expects to transform the understanding of granular materials and their behaviour by establishing explicit links between the macroscopic responses of the materials and their evolving microstructural properties. This should lead to revolutionary constitutive models for granular materials that possess true mechanisms of evolving grain-scale structures. The proliferation of these new models should allow development of reliable predictive computational tools for the modelling and assessment of field-scale failure involving granular materials, enhancing the capability to assess the integrity and stability of earth structures, and benefitting the Australian economy, environment and public safety.Read moreRead less