Near Unsupervised Learning for Early Discovery of Novel Patterns: Methods, Scalability and Label Dependability. This project aims to predict the unknown class labels using the existing small number of class labels. The outcomes of the project have direct relevance to the economy, environment, energy and health sectors due to the abundance of data coming out of these areas. For example, if an oncogene, a gene that can cause cancer when mutated can be found using data with only few labels and a la ....Near Unsupervised Learning for Early Discovery of Novel Patterns: Methods, Scalability and Label Dependability. This project aims to predict the unknown class labels using the existing small number of class labels. The outcomes of the project have direct relevance to the economy, environment, energy and health sectors due to the abundance of data coming out of these areas. For example, if an oncogene, a gene that can cause cancer when mutated can be found using data with only few labels and a large amount of unlabelled data, the costs and time needed for lab experimentation can be greatly reduced enabling pharmaceutical companies to develop corresponding medicines quicker. It will not only save more lives but also generates millions of dollars of income.Read moreRead less
Intelligent Image Processing Techniques for Novel Biomarker Discovery. This project will make an impact on Australia's international research profile by seeking a solution to a worldwide challenging problem in biomarker discovery for the detection of diseases at an early stage which requires the incorporation of the skills and knowledge from biology, medicine, engineering, computer science, and information technology. The successful outcomes of this research will make an impact on Australia's e ....Intelligent Image Processing Techniques for Novel Biomarker Discovery. This project will make an impact on Australia's international research profile by seeking a solution to a worldwide challenging problem in biomarker discovery for the detection of diseases at an early stage which requires the incorporation of the skills and knowledge from biology, medicine, engineering, computer science, and information technology. The successful outcomes of this research will make an impact on Australia's engagement in using advanced image analysis and intelligent methods for the emerging research and development of targeted drug discovery. Read moreRead less
Evolutionary algorithms for problems in functional genomics data analysis. Skin cancer has a high incidence in the Australian population. Schizophrenia is a psychiatric disorder that affects a significant proportion of the population worldwide. Both illnesses have genetic roots and can be triggered by environmental factors. We will uncover genetic relationship to disease and their responses to environmental conditions using computational methods and mathematical algorithms that can aid in the de ....Evolutionary algorithms for problems in functional genomics data analysis. Skin cancer has a high incidence in the Australian population. Schizophrenia is a psychiatric disorder that affects a significant proportion of the population worldwide. Both illnesses have genetic roots and can be triggered by environmental factors. We will uncover genetic relationship to disease and their responses to environmental conditions using computational methods and mathematical algorithms that can aid in the determination of function, especially in disease states. Understanding the complex genetic interactions that trigger these illnesses would give great benefits in preventive health care, skin cancer and schizophrenia genetic basis, and may lay the ground for building new methods for "personalized medicine".
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An Automated Bioimaging System for High-Content Cell-Cycle Screening. 1) Providing a better understanding of the biological complexities
that will advance knowledge in life science research and facilitate the development of new anti-cancer drugs.
2) Supporting Australian academic institutions in a challenging field of innovative research through international, interdisciplinary collaborations, and publications in journals of high quality scientific research.
3) Providing research training ....An Automated Bioimaging System for High-Content Cell-Cycle Screening. 1) Providing a better understanding of the biological complexities
that will advance knowledge in life science research and facilitate the development of new anti-cancer drugs.
2) Supporting Australian academic institutions in a challenging field of innovative research through international, interdisciplinary collaborations, and publications in journals of high quality scientific research.
3) Providing research training in a research venture that requires expertise and collaboration in the disciplines of biology, engineering, computer science, and mathematics.
4) Bringing economic and social benefits for Australia by enhancing important industries and existing technologies in medicine, and biotechnology.
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On-line and Incremental EM-based Neural Networks: Application to Hospital Utlilization and Gene Expression Data. Artificial neural networks have been widely applied as universal classifiers in many fields, such as biomedicine. However, misunderstanding of fundamental statistical principles, which can cause misleading findings, has been frequently observed in the literature. This project aims to integrate statistical methodologies in neural networks to provide a unified approach to improve its ....On-line and Incremental EM-based Neural Networks: Application to Hospital Utlilization and Gene Expression Data. Artificial neural networks have been widely applied as universal classifiers in many fields, such as biomedicine. However, misunderstanding of fundamental statistical principles, which can cause misleading findings, has been frequently observed in the literature. This project aims to integrate statistical methodologies in neural networks to provide a unified approach to improve its applicability and efficiency in implementation. The system developed from this proposed cross-disciplinary research will be applied to hospital utilization data (hospital morbidity database, Western Australia) and gene expression data (DNA microarrays databases, Harvard University). This collaborative research will advance the international standard of Australian research communities.
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Special Research Initiatives - Grant ID: SR0354599
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
An Integrated Intelligent Bio-machines Network. The increasing use of computing, advanced materials, electronic control with biological or human applications has provided the need to strengthen the nexus of these discipline areas. This proposal is expected to identify the critical areas of integration that can be realistically developed into meaningful technologies and products in the short-to-medium term. The significance of this network is to enhance the science and technology required for sy ....An Integrated Intelligent Bio-machines Network. The increasing use of computing, advanced materials, electronic control with biological or human applications has provided the need to strengthen the nexus of these discipline areas. This proposal is expected to identify the critical areas of integration that can be realistically developed into meaningful technologies and products in the short-to-medium term. The significance of this network is to enhance the science and technology required for systems and products such as bionic eyes, legs, muscles and larynxes. These products and systems characterize the essence of this network: The integration of hardware and software with wetware (Humans).Read moreRead less
AUSLearn: AUtomated Sample Learning for Object Recognition. This project aims to enable computers to learn how to effectively use training samples for object recognition. Training sample is the only source used by computers to learn recognising objects. This project creates a new research direction that will enable the first full exploration of the power of samples. The aims will be enabled by leveraging the recent advances in reinforcement learning, fast training algorithms, and by developing n ....AUSLearn: AUtomated Sample Learning for Object Recognition. This project aims to enable computers to learn how to effectively use training samples for object recognition. Training sample is the only source used by computers to learn recognising objects. This project creates a new research direction that will enable the first full exploration of the power of samples. The aims will be enabled by leveraging the recent advances in reinforcement learning, fast training algorithms, and by developing novel deep learning algorithms. The new algorithms will benefit a wide range of applications, e.g. to effectively use car crash training samples for accurately identifying potential road crashes in transport and to effectively use rare medical imaging training data for robustly diagnosing diseases in health.Read moreRead less
Computational Intelligence Methods for Financial Applications. Complex financial problems can be better addressed with software that can learn from available data and adapt to environmental changes. It is therefore essential to develop technologies that enable prediction and optimisation in constrained and dynamic environments. There are currently some limitations in existing business decision support systems despite their ubiquity providing an opportunity for Australia to be at the forefront as ....Computational Intelligence Methods for Financial Applications. Complex financial problems can be better addressed with software that can learn from available data and adapt to environmental changes. It is therefore essential to develop technologies that enable prediction and optimisation in constrained and dynamic environments. There are currently some limitations in existing business decision support systems despite their ubiquity providing an opportunity for Australia to be at the forefront as new standards in the field are developed. Furthermore, the fund management industry (particularly superannuation) is significant to the Australian economy and development of this technology has the potential to enhance its performance and reputation.Read moreRead less
Improving the modelling of insolvency risk and financial health assessment of global companies using hybrid intelligent techniques. The social and economic impacts of corporate collapses are severe, and much research has modelled financial health and insolvency risk of companies. Most research, however, uses simple and out-dated financial ratios used by Altman (1968), and attempts to develop a universal model valid for specific (non-global) markets. Our approach is to improve the relevance of th ....Improving the modelling of insolvency risk and financial health assessment of global companies using hybrid intelligent techniques. The social and economic impacts of corporate collapses are severe, and much research has modelled financial health and insolvency risk of companies. Most research, however, uses simple and out-dated financial ratios used by Altman (1968), and attempts to develop a universal model valid for specific (non-global) markets. Our approach is to improve the relevance of the information provided to the models (including measures of strategy, recent accounting metrics, global context). We also challenge the merits of a universal model by developing and testing a novel hybrid intelligent approach combining neural networks, genetic algorithms and self-organising maps, applicable to global markets.Read moreRead less
Modelling and Removal of Noise and Artefacts in Surveillance and Security Video for Forensic Image Analysis and Enhancement. This project spearheads research in advanced digital image and video processing technology, placing Australia at the forefront of both theoretical and applied research to safeguard Australia. It tackles fundamental issues identified in our earlier research in this area and consulting work for Victoria and NSW Police Departments in forensic investigations since 2000. Althou ....Modelling and Removal of Noise and Artefacts in Surveillance and Security Video for Forensic Image Analysis and Enhancement. This project spearheads research in advanced digital image and video processing technology, placing Australia at the forefront of both theoretical and applied research to safeguard Australia. It tackles fundamental issues identified in our earlier research in this area and consulting work for Victoria and NSW Police Departments in forensic investigations since 2000. Although the main investigation focuses on video surveillance and security systems for public safety, policing, crime prevention and border control, the outcomes of the investigation will have other applications, including digital photography for fine-art, medical imaging, picture archiving and communication systems for telemedicine and rural healthcare systems.Read moreRead less