Mechanisms And Therapies In Cardiovascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$8,360,700.00
Summary
Cardiovascular disease (CVD) claims 1 person every 10 min in Australia and causes 1 in 3 deaths worldwide. The molecular and cellular processes underlying atherosclerosis, vascular injury and thrombosis are highly complex and not well understood. A multifaceted approach is needed to effectively address these key challenges. This Program brings together world experts in these areas to interrogate gaps in our basic understanding of CVD, and to develop novel therapies for CVD patients by exploiting ....Cardiovascular disease (CVD) claims 1 person every 10 min in Australia and causes 1 in 3 deaths worldwide. The molecular and cellular processes underlying atherosclerosis, vascular injury and thrombosis are highly complex and not well understood. A multifaceted approach is needed to effectively address these key challenges. This Program brings together world experts in these areas to interrogate gaps in our basic understanding of CVD, and to develop novel therapies for CVD patients by exploiting new knowledge through integrated research.Read moreRead less
The Tasmanian Healthy Brain Project: A Longitudinal Intervention Study To Reduce The Risk Of Ageing-related Cognitive Decline And Dementia
Funder
National Health and Medical Research Council
Funding Amount
$878,792.00
Summary
It has been proposed that engagement in purposeful complex mental stimulation provides protection against dementia. The Tasmanian Healthy Brain Project (THBP) is a unique, large-scale prospective trial that examines whether university-level study in older adult population reduces ageing-related cognitive decline and risk of dementia. This project will also examine how an individual’s genetic profile may influence the potential benefits of complex mental stimulation as well as risk of dementia.
An upgraded pulsar timing array for gravitational wave detection. Millisecond pulsars are remarkably regularly-rotating neutron stars that offer the opportunity to detect gravitational waves via the technique known as pulsar timing. Australia has long been a world leader in the discovery and timing of millisecond pulsars, and the Parkes pulsar timing array is one of three major programmes in the world aimed at making the first direct detection of gravitational waves in any frequency band. This p ....An upgraded pulsar timing array for gravitational wave detection. Millisecond pulsars are remarkably regularly-rotating neutron stars that offer the opportunity to detect gravitational waves via the technique known as pulsar timing. Australia has long been a world leader in the discovery and timing of millisecond pulsars, and the Parkes pulsar timing array is one of three major programmes in the world aimed at making the first direct detection of gravitational waves in any frequency band. This project is designed to capitalise on Australia's position of strength in this field by extending the Parkes Pulsar Timing Array dataset (PPTA) so that it has the best chance of detecting gravitational waves in the nanohertz regime until the SKA pathfinders start to come online in 2017.Read moreRead less
Weighing the Universe using fast radio bursts. Fast radio bursts are a newly-discovered astronomical phenomenon whose millisecond-timescale emission occurs at cosmological distances, rendering them exceptional probes of the matter that lies in intergalactic space. This project aims to measure the positions and obtain the distances to these bursts to make a direct measurement of the density of ordinary matter in the Universe, at least 50 per cent of which is believed to remain undetected in inter ....Weighing the Universe using fast radio bursts. Fast radio bursts are a newly-discovered astronomical phenomenon whose millisecond-timescale emission occurs at cosmological distances, rendering them exceptional probes of the matter that lies in intergalactic space. This project aims to measure the positions and obtain the distances to these bursts to make a direct measurement of the density of ordinary matter in the Universe, at least 50 per cent of which is believed to remain undetected in intergalactic space. This project will measure the distribution of this missing matter, and find how it has evolved throughout the history of the Universe. This will provide significant benefits, such as addressing two fundamental questions about our Universe: how much matter does it contain, and has a large fraction of it hitherto evaded detection in intergalactic space?Read moreRead less
Motor Functioning In Young People With Attention Deficit Hyperactivity Disorder – Combined Type: A Three-dimensional Motion Analysis Study.
Funder
National Health and Medical Research Council
Funding Amount
$477,065.00
Summary
Attention deficit hyperactivity disorder –combined type (ADHD-CT) is a complex neuropsychiatric disorder with a progressively devastating impact on psychosocial development. The first objective of this study is to use 3D-motion analysis to ‘probe’ the underlying brain dysfunction which characterises ADHD-CT. The second objective of this study is to improve our understanding of the link between movement problems, and (a) injury proneness, and (b) social-communicative problems, in children with AD ....Attention deficit hyperactivity disorder –combined type (ADHD-CT) is a complex neuropsychiatric disorder with a progressively devastating impact on psychosocial development. The first objective of this study is to use 3D-motion analysis to ‘probe’ the underlying brain dysfunction which characterises ADHD-CT. The second objective of this study is to improve our understanding of the link between movement problems, and (a) injury proneness, and (b) social-communicative problems, in children with ADHD-CT.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100206
Funder
Australian Research Council
Funding Amount
$403,000.00
Summary
Probing ultralight bosons with black holes and gravitational waves. This project aims to search for gravitational waves from ultralight boson clouds around black holes and to investigate the boson properties. It expects to generate new knowledge on currently undiscovered particles by combining cutting-edge theories and innovative signal-processing techniques. These particles are predicted to solve problems in particle and high-energy physics and are compelling dark matter candidates. Expected ou ....Probing ultralight bosons with black holes and gravitational waves. This project aims to search for gravitational waves from ultralight boson clouds around black holes and to investigate the boson properties. It expects to generate new knowledge on currently undiscovered particles by combining cutting-edge theories and innovative signal-processing techniques. These particles are predicted to solve problems in particle and high-energy physics and are compelling dark matter candidates. Expected outcomes include high-profile constraints on the particle properties and potential detection of new particles, new data-analysis techniques, and significantly enhanced capacity to build international and interdisciplinary collaborations. These should bring significant benefits to fundamental physics and cosmology.Read moreRead less
Ultra-sensitive third-generation gravitational wave detectors. Second-generation gravitational wave detectors that will directly detect gravitational waves for the first time are currently being assembled. Their sensitivity will be limited by intrinsic thermal motion of the atoms in the mirror coatings and the quantum nature of the laser beams in the detectors. This project aims to develop new designs with the aim of circumventing these limitations and developing the ultra-sensitive optical metr ....Ultra-sensitive third-generation gravitational wave detectors. Second-generation gravitational wave detectors that will directly detect gravitational waves for the first time are currently being assembled. Their sensitivity will be limited by intrinsic thermal motion of the atoms in the mirror coatings and the quantum nature of the laser beams in the detectors. This project aims to develop new designs with the aim of circumventing these limitations and developing the ultra-sensitive optical metrology required to realise those designs. It is expected that the increased sensitivity of these third-generation detectors will allow more detailed measurement of the gravitational wave signals and provide unprecedented understanding of some of the most violent events in the universe.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100008
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
Australian Seismic Imaging Array. The project aims to create a facility for developing techniques for imaging the deep earth and the surface motion in ambient seismic waves created by wind, waves and human activity. The techniques will enable sources of seismic vibrations to be identified and suppressed, and will allow mapping techniques to be developed for monitoring and discovery of resources such as ground water. Gravitational wave researchers will benefit from the ability to suppress seismic ....Australian Seismic Imaging Array. The project aims to create a facility for developing techniques for imaging the deep earth and the surface motion in ambient seismic waves created by wind, waves and human activity. The techniques will enable sources of seismic vibrations to be identified and suppressed, and will allow mapping techniques to be developed for monitoring and discovery of resources such as ground water. Gravitational wave researchers will benefit from the ability to suppress seismic vibrations, while geophysicists will benefit from new techniques and training. Read moreRead less