Regulation of Cellulose Biosynthesis in Commercially Important Cereal Crop Species. The long term strategic research alliance with DuPont Pioneer will lead to the development of breakthrough science in emerging technologies that are relevant: a) to agricultural production, b) to human health and c) to renewable bio-fuel production from crop residues. The alliance will attract significant international investment in Australian research and foster an intellectual environment for world-class resear ....Regulation of Cellulose Biosynthesis in Commercially Important Cereal Crop Species. The long term strategic research alliance with DuPont Pioneer will lead to the development of breakthrough science in emerging technologies that are relevant: a) to agricultural production, b) to human health and c) to renewable bio-fuel production from crop residues. The alliance will attract significant international investment in Australian research and foster an intellectual environment for world-class research training of postgraduate students and postdoctoral scientists, in both a higher education and an industry context.Read moreRead less
Carbon neutral communities: making the transition. This project has well defined National benefits, both economic and social, for the collaborative partners, the business community, policy makers, community groups and the broader Australian community. It contributes toward NRP 1, through developing practical measures for reducing GHG emissions in Australian urban areas, and strategies for overcoming barriers to greater uptake of energy efficiency and alternative technologies; and helping Austra ....Carbon neutral communities: making the transition. This project has well defined National benefits, both economic and social, for the collaborative partners, the business community, policy makers, community groups and the broader Australian community. It contributes toward NRP 1, through developing practical measures for reducing GHG emissions in Australian urban areas, and strategies for overcoming barriers to greater uptake of energy efficiency and alternative technologies; and helping Australia to meet its greenhouse reduction targets. The project economic benefits to through energy savings; stimulating innovation in urban design, building design and transport use; promoting new business opportunities; and encouraging more sustainable lifestyle decisions. Read moreRead less
Campus: Building Modern Australian Universities. This project plans to examine the post-World War Two evolution of the Australian university campus. Modern campuses created opportunities for the realisation of innovative solutions in urban planning, architecture and landscape. The project plans to reveal the physical impacts of political, institutional, social and cultural demands through comparative thematic investigation, digital visualisation and detailed case studies. Foregrounding landscape ....Campus: Building Modern Australian Universities. This project plans to examine the post-World War Two evolution of the Australian university campus. Modern campuses created opportunities for the realisation of innovative solutions in urban planning, architecture and landscape. The project plans to reveal the physical impacts of political, institutional, social and cultural demands through comparative thematic investigation, digital visualisation and detailed case studies. Foregrounding landscape and site, the project aims to establish new historical knowledge, identify campuses as catalysts for urban thinking, and demonstrate strategies for their conservation and adaptation to meet future needs in the tertiary sector.Read moreRead less
Recomputing the canon: using computational methods to develop an alternative understanding of the history of 20th century architecture. Because buildings are designed to last for many generations, and they represent a substantial economic investment, architecture remains one of the most tangible and persistent reflections of a culture's spiritual, social and political values. This is why it is said, to understand architecture is to understand society and its principles. This research develops an ....Recomputing the canon: using computational methods to develop an alternative understanding of the history of 20th century architecture. Because buildings are designed to last for many generations, and they represent a substantial economic investment, architecture remains one of the most tangible and persistent reflections of a culture's spiritual, social and political values. This is why it is said, to understand architecture is to understand society and its principles. This research develops an alternative history of 20th century architecture that will not only allow for a deeper understanding of, and appreciation for, our own constructed heritage, but will also inform the design and production of future buildings which are both socially and culturally responsive.Read moreRead less
The Role Of UPF3B And Nonsense Mediated MRNA Decay Surveillance In The Pathology Of Intellectual Disability.
Funder
National Health and Medical Research Council
Funding Amount
$789,954.00
Summary
Proper functioning of the nonsense mediated mRNA decay (NMD or 'mRNA police') is crucial for any cell to ensure normal development and function. When NMD is compromised the outcome is learning and memory problems, autism or schizophrenia. Under this project we study malfunctioning NMD using stem and neuronal cells derived from patients' skin cells. Some of the affected genes might be considered for therapeutic interventions. NMD is relevant to 1000s of human disorders and as such it is of fundam ....Proper functioning of the nonsense mediated mRNA decay (NMD or 'mRNA police') is crucial for any cell to ensure normal development and function. When NMD is compromised the outcome is learning and memory problems, autism or schizophrenia. Under this project we study malfunctioning NMD using stem and neuronal cells derived from patients' skin cells. Some of the affected genes might be considered for therapeutic interventions. NMD is relevant to 1000s of human disorders and as such it is of fundamental importance.Read moreRead less
Cultural heritage in the sustainability of remote planned communities. The project responds to one objective of ARC Linkage grants 'to support collaborative research on issues of benefit to regional and rural communities'. It will assist remote settlements struggling for survival because of the demise or downturn of specialised employment bases. Focusing on the heritage importance and attraction of planned settlements in particular, economic and social benefits include increased knowledge of the ....Cultural heritage in the sustainability of remote planned communities. The project responds to one objective of ARC Linkage grants 'to support collaborative research on issues of benefit to regional and rural communities'. It will assist remote settlements struggling for survival because of the demise or downturn of specialised employment bases. Focusing on the heritage importance and attraction of planned settlements in particular, economic and social benefits include increased knowledge of the design history and heritage of Australian post-WW2 planned special-purpose towns in international perspective; strategies for identifying how cultural heritage might be harnessed to revitalise and sustain at risk communities; and postgraduate training in applied history and heritage. Read moreRead less
Innovative procurement theories to optimise education per cost of school. Innovative procurement theories to optimise education per cost of school. This project aims to develop a whole-of-life procurement decision-making framework so schools can make delivering better education more cost effective. This framework—which draws on state-of-the-art and Nobel prize-winning theories and a new theory the project will develop—will be used in government and private schools. The effectiveness of this fram ....Innovative procurement theories to optimise education per cost of school. Innovative procurement theories to optimise education per cost of school. This project aims to develop a whole-of-life procurement decision-making framework so schools can make delivering better education more cost effective. This framework—which draws on state-of-the-art and Nobel prize-winning theories and a new theory the project will develop—will be used in government and private schools. The effectiveness of this framework in improving schools will be shown using a new approach to make school facilities deliver educational outcomes and account for their total production and transaction costs. This research is expected to deliver more efficient ways to future-proof schools to create a well performing school system and more resilient infrastructure vital to Australia’s future prosperity.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150100328
Funder
Australian Research Council
Funding Amount
$374,000.00
Summary
Minimising transaction costs in Murray-Darling Basin water reform. Transaction costs provide social, economic, environmental and political barriers to the effectiveness of water reallocation policy in Australia. These costs are often difficult to quantify, but potentially are subject to measurement. This project aims to develop a comprehensive transaction cost framework for the Murray-Darling Basin that can be used to capture and measure transaction costs related to water policy. Further, the sc ....Minimising transaction costs in Murray-Darling Basin water reform. Transaction costs provide social, economic, environmental and political barriers to the effectiveness of water reallocation policy in Australia. These costs are often difficult to quantify, but potentially are subject to measurement. This project aims to develop a comprehensive transaction cost framework for the Murray-Darling Basin that can be used to capture and measure transaction costs related to water policy. Further, the scope of the cost measurement will involve a variety of data collection approaches. Outcomes include better water policy and management from arrangements that will span the divide between the Basin Plan and its implementation.Read moreRead less
Increasing confidence in Australian carbon disclosures. This project aims to investigate whether carbon disclosures made by Australian resource firms are less than actual emissions (i.e., carbonwashing) using satellite imagery technology. New knowledge will be generated by triangulating carbonwashing information against firm data, such as valuation, other disclosures, and hiring practices, to understand if and how carbonwashing impacts firm values and organisational controls. Expected outcomes i ....Increasing confidence in Australian carbon disclosures. This project aims to investigate whether carbon disclosures made by Australian resource firms are less than actual emissions (i.e., carbonwashing) using satellite imagery technology. New knowledge will be generated by triangulating carbonwashing information against firm data, such as valuation, other disclosures, and hiring practices, to understand if and how carbonwashing impacts firm values and organisational controls. Expected outcomes include improved ways to detect carbonwashing and its relationship to management control weaknesses, benefiting all stakeholders (including investors and regulators) in supporting government-proposed reforms to the Australian Safeguard Mechanism in instilling confidence in Australian carbon disclosures.Read moreRead less
About one in eight known genetic disorders involve DNA alteration that activates a cellular quality control mechanism that disables the affected gene. This mechanism is more efficient in some individuals than others. It can influence disease outcomes and severity. We will engineer and apply tools and models to measure and manipulate this crucial cellular mechanism. This will allow us to predict disease severity as well as to intervene where a manipulation of this mechanism will be beneficial.