Making better decisions about built assets: learning by doing. This research will assist the built environment professions and their clients to make better decisions about new developments through a novel 'learning by doing' approach. Used successfully in other fields such as natural resource management, this idea will capitalise on the large number of asset investments undertaken to benchmark original stakeholder intentions and aspirations against the reality of current performance. Decisions w ....Making better decisions about built assets: learning by doing. This research will assist the built environment professions and their clients to make better decisions about new developments through a novel 'learning by doing' approach. Used successfully in other fields such as natural resource management, this idea will capitalise on the large number of asset investments undertaken to benchmark original stakeholder intentions and aspirations against the reality of current performance. Decisions will be re-evaluated in the context of contemporary economic, social and environmental criteria to enable existing multi-criteria models to deliver more sustainable outcomes that are also feasible and in the national interest, and consequently minimise the industry's current exposure to future climate change.Read moreRead less
Strategic Assessment of Building Adaptive Reuse Opportunities. This research will review a large database of existing buildings, many of which have exceeded their useful life. An innovative model will be developed to enable Australia's building and property industries to identify the most viable opportunities for building adaptive reuse. The model will integrate financial, environmental and social sustainability, enabling community stakeholders to make informed decisions with widespread benefits ....Strategic Assessment of Building Adaptive Reuse Opportunities. This research will review a large database of existing buildings, many of which have exceeded their useful life. An innovative model will be developed to enable Australia's building and property industries to identify the most viable opportunities for building adaptive reuse. The model will integrate financial, environmental and social sustainability, enabling community stakeholders to make informed decisions with widespread benefits. The research is aligned with the national priority area: An Environmentally Sustainable Australia: Transforming Existing Industries. The expertise developed in this project will be regionally and internationally applicable, providing momentum for the growing adaptive design and conservation market.Read moreRead less
Carbon neutral communities: making the transition. This project has well defined National benefits, both economic and social, for the collaborative partners, the business community, policy makers, community groups and the broader Australian community. It contributes toward NRP 1, through developing practical measures for reducing GHG emissions in Australian urban areas, and strategies for overcoming barriers to greater uptake of energy efficiency and alternative technologies; and helping Austra ....Carbon neutral communities: making the transition. This project has well defined National benefits, both economic and social, for the collaborative partners, the business community, policy makers, community groups and the broader Australian community. It contributes toward NRP 1, through developing practical measures for reducing GHG emissions in Australian urban areas, and strategies for overcoming barriers to greater uptake of energy efficiency and alternative technologies; and helping Australia to meet its greenhouse reduction targets. The project economic benefits to through energy savings; stimulating innovation in urban design, building design and transport use; promoting new business opportunities; and encouraging more sustainable lifestyle decisions. Read moreRead less
Campus: Building Modern Australian Universities. This project plans to examine the post-World War Two evolution of the Australian university campus. Modern campuses created opportunities for the realisation of innovative solutions in urban planning, architecture and landscape. The project plans to reveal the physical impacts of political, institutional, social and cultural demands through comparative thematic investigation, digital visualisation and detailed case studies. Foregrounding landscape ....Campus: Building Modern Australian Universities. This project plans to examine the post-World War Two evolution of the Australian university campus. Modern campuses created opportunities for the realisation of innovative solutions in urban planning, architecture and landscape. The project plans to reveal the physical impacts of political, institutional, social and cultural demands through comparative thematic investigation, digital visualisation and detailed case studies. Foregrounding landscape and site, the project aims to establish new historical knowledge, identify campuses as catalysts for urban thinking, and demonstrate strategies for their conservation and adaptation to meet future needs in the tertiary sector.Read moreRead less
Lifetime Affordable Housing in Australia: Integrating environmental performance and affordability. Existing dwellings and the locations of suburban housing with respect to employment centres result in significant greenhouse gas emissions. Water and other environmental issues are also important in housing performance, and there is currently a perceived trade-off between these factors and the affordability of housing. For the first time in Australia, this study will focus on overcoming this appare ....Lifetime Affordable Housing in Australia: Integrating environmental performance and affordability. Existing dwellings and the locations of suburban housing with respect to employment centres result in significant greenhouse gas emissions. Water and other environmental issues are also important in housing performance, and there is currently a perceived trade-off between these factors and the affordability of housing. For the first time in Australia, this study will focus on overcoming this apparent policy dilemma. The research will inform future housing policy in strengthening Australia's economic and social fabric, while contributing towards Australia's National Research Priority 1 'Environmentally Sustainable Australia'. Outcomes will provide significant national economic, social, water use and greenhouse gas benefits for Australia.Read moreRead less
Integrating Immunity And Genetics In Follicular Lymphoma To Establish A Prognostic Score Fit For The Modern Era
Funder
National Health and Medical Research Council
Funding Amount
$1,377,174.00
Summary
Follicular lymphoma (FL) is divided into early and advanced stages. Early stage FL is frequently cured, but there is no way to identify who will be cured and who won't. By contrast advanced stage FL is incurable. Our unique access to well-annotated clinical trial and population based cohorts allows us to perform a detailed biological comparison of early and advanced FL, to gain a deeper understanding of the impediments to eradicating the disease, and to predict outcome to conventional therapy.
Innovative procurement theories to optimise education per cost of school. Innovative procurement theories to optimise education per cost of school. This project aims to develop a whole-of-life procurement decision-making framework so schools can make delivering better education more cost effective. This framework—which draws on state-of-the-art and Nobel prize-winning theories and a new theory the project will develop—will be used in government and private schools. The effectiveness of this fram ....Innovative procurement theories to optimise education per cost of school. Innovative procurement theories to optimise education per cost of school. This project aims to develop a whole-of-life procurement decision-making framework so schools can make delivering better education more cost effective. This framework—which draws on state-of-the-art and Nobel prize-winning theories and a new theory the project will develop—will be used in government and private schools. The effectiveness of this framework in improving schools will be shown using a new approach to make school facilities deliver educational outcomes and account for their total production and transaction costs. This research is expected to deliver more efficient ways to future-proof schools to create a well performing school system and more resilient infrastructure vital to Australia’s future prosperity.Read moreRead less
Responding to Climate Change: Australia's Environmental Law and Regulatory Framework. Climate change presents Australia with unparalleled sustainability challenges. Impacts on environmental resources will require an integrated legal and socio-economic regulatory response. An effective and adaptable environmental law framework will be crucial for adaptation and mitigation measures. The project addresses this need by undertaking a comprehensive, interdisciplinary evaluation of Australia's legal ca ....Responding to Climate Change: Australia's Environmental Law and Regulatory Framework. Climate change presents Australia with unparalleled sustainability challenges. Impacts on environmental resources will require an integrated legal and socio-economic regulatory response. An effective and adaptable environmental law framework will be crucial for adaptation and mitigation measures. The project addresses this need by undertaking a comprehensive, interdisciplinary evaluation of Australia's legal capacity to respond to climate change, so identifying appropriate governance structures and regulatory tools. This analysis is vital to positioning Australian environmental law to manage climate change impacts and associated social, ecological and economic costs and to ensure compliance with international obligations.Read moreRead less
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
Evolution And Function Of A Novel Lateral Flagellar Locus, Flag-2, In Pathogenic Escherichia Coli
Funder
National Health and Medical Research Council
Funding Amount
$465,158.00
Summary
This project will study how the bacteria that cause infant diarrhoea colonize the intestine and induce disease. We have identified a novel genetic region that allows E. coli to survive and persist in the intestine. Similar genes are also present in closely related organisms. This project will help us to undestand how new diseases evolve and emerge and may lead to the development of new vaccines to protect against infant diarrhoea.