The use of nudges as a local government environmental policy instrument. This project aims to design and rigorously test a range of behavioural nudges to improve the environmental behaviour of residents in the ACT, with a focus on adoption of low carbon technologies and the use of public transport. In partnership with the ACT Government, the proposal leverages recent research on cognitive biases to develop novel interventions and evaluate their effects via randomised controlled trials. Expected ....The use of nudges as a local government environmental policy instrument. This project aims to design and rigorously test a range of behavioural nudges to improve the environmental behaviour of residents in the ACT, with a focus on adoption of low carbon technologies and the use of public transport. In partnership with the ACT Government, the proposal leverages recent research on cognitive biases to develop novel interventions and evaluate their effects via randomised controlled trials. Expected outcomes include new concepts for citizen-government interactions; advanced knowledge in public policy and behavioural economics; a new statistical programming tool; new methods to optimise policy and practice; and positive environmental and economic impacts for local governments and individuals.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0454052
Funder
Australian Research Council
Funding Amount
$733,595.00
Summary
Tandem Matrix-Assisted Laser Desorption/Ionisation Time-Of-Flight Mass Spectrometer and Robots for High Throughput Proteomics Analysis. This proposal seeks to establish the capacity to perform high-energy tandem mass spectrometry on a high throughput basis, through purchase and coordinated operation of a Matrix-Assisted Laser Desorption/Ionisation - Time of Flight / Time of Flight - Mass Spectrometer and ancillary equipment, to enhance the proteomics expertise, infrastructure and research plans ....Tandem Matrix-Assisted Laser Desorption/Ionisation Time-Of-Flight Mass Spectrometer and Robots for High Throughput Proteomics Analysis. This proposal seeks to establish the capacity to perform high-energy tandem mass spectrometry on a high throughput basis, through purchase and coordinated operation of a Matrix-Assisted Laser Desorption/Ionisation - Time of Flight / Time of Flight - Mass Spectrometer and ancillary equipment, to enhance the proteomics expertise, infrastructure and research plans of a network of institutions from Queensland and New South Wales and their collaborators. Access to such instrumentation is critical to high level achievement in proteomics, a key platform technology for National Research Priorities relating to Frontier Technologies. No comparable instrument currently exists in Australia.Read moreRead less
CesA (cellulose synthase) genes of Arabidopsis; all doing the same job or specialists cooperating to make the most abundant biopolymer. The biosphere makes more cellulose than any other polymer with fibre industries depending on its physical properties and atmospheric carbon dioxide levels depending on its stability as a carbon sink. Demonstrations that cellulose production needs CesA genes drove recent progress in elucidating the mechanism of synthesis. CesA proteins all look very similar but i ....CesA (cellulose synthase) genes of Arabidopsis; all doing the same job or specialists cooperating to make the most abundant biopolymer. The biosphere makes more cellulose than any other polymer with fibre industries depending on its physical properties and atmospheric carbon dioxide levels depending on its stability as a carbon sink. Demonstrations that cellulose production needs CesA genes drove recent progress in elucidating the mechanism of synthesis. CesA proteins all look very similar but if all do the same job, why do plants need so many and why do none seem redundant? We will make gene interchanges in transgenic plants, build chimeric genes and identify where each CesA protein operates. This will identify their individual and cooperative contributions to cellulose production.Read moreRead less
Embedded emissions accounting: frameworks for trade in a net-zero world. This project aims to inform Government on potential accounting frameworks for greenhouse emissions embedded in tradable products. Public frameworks are urgently needed given the emergence internationally of trade-related climate policies such as carbon border adjustment mechanisms. The project expects to contribute to global knowledge on embedded emissions frameworks by combining economic, engineering, science and policy pe ....Embedded emissions accounting: frameworks for trade in a net-zero world. This project aims to inform Government on potential accounting frameworks for greenhouse emissions embedded in tradable products. Public frameworks are urgently needed given the emergence internationally of trade-related climate policies such as carbon border adjustment mechanisms. The project expects to contribute to global knowledge on embedded emissions frameworks by combining economic, engineering, science and policy perspectives. Expected outcomes include improved: capability within Government; understanding among Australian stakeholders; and integration with international approaches. Expected benefits include lower regulatory barriers to global emissions reductions, and fairer access to international markets for Australian producers. Read moreRead less
Carbon neutral communities: making the transition. This project has well defined National benefits, both economic and social, for the collaborative partners, the business community, policy makers, community groups and the broader Australian community. It contributes toward NRP 1, through developing practical measures for reducing GHG emissions in Australian urban areas, and strategies for overcoming barriers to greater uptake of energy efficiency and alternative technologies; and helping Austra ....Carbon neutral communities: making the transition. This project has well defined National benefits, both economic and social, for the collaborative partners, the business community, policy makers, community groups and the broader Australian community. It contributes toward NRP 1, through developing practical measures for reducing GHG emissions in Australian urban areas, and strategies for overcoming barriers to greater uptake of energy efficiency and alternative technologies; and helping Australia to meet its greenhouse reduction targets. The project economic benefits to through energy savings; stimulating innovation in urban design, building design and transport use; promoting new business opportunities; and encouraging more sustainable lifestyle decisions. Read moreRead less
Lifetime Affordable Housing in Australia: Integrating environmental performance and affordability. Existing dwellings and the locations of suburban housing with respect to employment centres result in significant greenhouse gas emissions. Water and other environmental issues are also important in housing performance, and there is currently a perceived trade-off between these factors and the affordability of housing. For the first time in Australia, this study will focus on overcoming this appare ....Lifetime Affordable Housing in Australia: Integrating environmental performance and affordability. Existing dwellings and the locations of suburban housing with respect to employment centres result in significant greenhouse gas emissions. Water and other environmental issues are also important in housing performance, and there is currently a perceived trade-off between these factors and the affordability of housing. For the first time in Australia, this study will focus on overcoming this apparent policy dilemma. The research will inform future housing policy in strengthening Australia's economic and social fabric, while contributing towards Australia's National Research Priority 1 'Environmentally Sustainable Australia'. Outcomes will provide significant national economic, social, water use and greenhouse gas benefits for Australia.Read moreRead less
Recomputing the canon: using computational methods to develop an alternative understanding of the history of 20th century architecture. Because buildings are designed to last for many generations, and they represent a substantial economic investment, architecture remains one of the most tangible and persistent reflections of a culture's spiritual, social and political values. This is why it is said, to understand architecture is to understand society and its principles. This research develops an ....Recomputing the canon: using computational methods to develop an alternative understanding of the history of 20th century architecture. Because buildings are designed to last for many generations, and they represent a substantial economic investment, architecture remains one of the most tangible and persistent reflections of a culture's spiritual, social and political values. This is why it is said, to understand architecture is to understand society and its principles. This research develops an alternative history of 20th century architecture that will not only allow for a deeper understanding of, and appreciation for, our own constructed heritage, but will also inform the design and production of future buildings which are both socially and culturally responsive.Read moreRead less
Bioeconomic Modelling of Marine Reserves. Australian waters contain a huge range of biodiversity, but are under threat from human activities. To face this challenge and resolve the problems of depleted fisheries and habitat destruction, innovative approaches are required to integrate marine biology with fisheries economics. The research meets this immediate need by developing bioeconomic models of marine reserves to determine reserve location and size, and analyse interactions between reserves a ....Bioeconomic Modelling of Marine Reserves. Australian waters contain a huge range of biodiversity, but are under threat from human activities. To face this challenge and resolve the problems of depleted fisheries and habitat destruction, innovative approaches are required to integrate marine biology with fisheries economics. The research meets this immediate need by developing bioeconomic models of marine reserves to determine reserve location and size, and analyse interactions between reserves and harvested areas under environmental uncertainty. The models will be developed using the latest developments in economics, biology and numerical methods and will be used to conserve Australia's marine biodiversity and improve fisheries management.Read moreRead less
Development Of Therapeutically Useful Human Artificial Chromosomes For Gene Delivery And Optimal Gene Expression
Funder
National Health and Medical Research Council
Funding Amount
$496,986.00
Summary
Gene therapy is an exciting new form of treatment for genetic disorders aimed at providing long-term correction of the problems at source - namely the affected gene. The biggest technical hurdle facing gene therapy is to be able to deliver the therapeutic genes efficiently and safely into patient cells. Many gene therapy protocols are currently being trialled clinically. These protocols, based mostly on the use of attenuated viruses to deliver the genes, carry potential risks to the patients in ....Gene therapy is an exciting new form of treatment for genetic disorders aimed at providing long-term correction of the problems at source - namely the affected gene. The biggest technical hurdle facing gene therapy is to be able to deliver the therapeutic genes efficiently and safely into patient cells. Many gene therapy protocols are currently being trialled clinically. These protocols, based mostly on the use of attenuated viruses to deliver the genes, carry potential risks to the patients in terms of infection, immune response, and germline modification. We have developed the first stage of a new technology for gene delivery that does not require the use of viruses. This technology is based on the generation of human artificial chromosomes, which are smaller versions of the naturally occurring chromosomes that carry all the genes inside our cells. Safety in these artificial chromosomes comes from the use of entirely human materials for their engineering. These artificial chromosomes also have other advantages over the viral approaches, including allowing large genes to be carried, and providing a permanent cure in a single treatment. We have already successfully constructed, published, and patented a number of first-generation human artificial chromosomes. The current project aims to complete the next proof-of-concept milestone towards the further development of this technology. Specifically, we propose to demonstrate the ability of the artificial chromosomes to carry genes and provide sustainable expression of these genes in cells and in animal models. Success in this study will allow the technology to proceed rapidly into commercialisation and clinical trial as a new improved tool for gene delivery and gene therapy.Read moreRead less
Innovative procurement theories to optimise education per cost of school. Innovative procurement theories to optimise education per cost of school. This project aims to develop a whole-of-life procurement decision-making framework so schools can make delivering better education more cost effective. This framework—which draws on state-of-the-art and Nobel prize-winning theories and a new theory the project will develop—will be used in government and private schools. The effectiveness of this fram ....Innovative procurement theories to optimise education per cost of school. Innovative procurement theories to optimise education per cost of school. This project aims to develop a whole-of-life procurement decision-making framework so schools can make delivering better education more cost effective. This framework—which draws on state-of-the-art and Nobel prize-winning theories and a new theory the project will develop—will be used in government and private schools. The effectiveness of this framework in improving schools will be shown using a new approach to make school facilities deliver educational outcomes and account for their total production and transaction costs. This research is expected to deliver more efficient ways to future-proof schools to create a well performing school system and more resilient infrastructure vital to Australia’s future prosperity.Read moreRead less