Sequence to Sequence: Rigorous Statistical and Mathematical Analysis of Biological Sequence Data. Comparative genomics is fundamental for developing an understanding of genes and their function. For example, using statistical and computational techniques, it was recently demonstrated that 60% of genes are conserved between fly and human. When the human gene that confers susceptibility to Parkinson's disease was transferred into the fly it caused symptoms similar to those seen in humans. The futu ....Sequence to Sequence: Rigorous Statistical and Mathematical Analysis of Biological Sequence Data. Comparative genomics is fundamental for developing an understanding of genes and their function. For example, using statistical and computational techniques, it was recently demonstrated that 60% of genes are conserved between fly and human. When the human gene that confers susceptibility to Parkinson's disease was transferred into the fly it caused symptoms similar to those seen in humans. The future development of 'personalized medicine' will rely upon understanding the function of human genes, as will progress in the agricultural sector. Rigorous statistical analysis and development of appropriate bioinformatic methods are crucial to biological sequence analysis in comparative genomics.Read moreRead less
Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant ....Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant contributions to the new and evolving priority research area of Bioinformation Science (including bioinformatics). Outcomes will include novel techniques for analysis and mining of post-genome data, with applications to developments in Bio-medicine and Bio-agricultureRead moreRead less
Discovery Indigenous Researchers Development - Grant ID: DI0989056
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Adoption and Effective Use of Information Communication Technologies in Indigenous Communities in Australia. This project on Indigenous use of the internet aims to identify the reasons why Indigenous Australians are 69% less likely to access the Internet than their non-Indigenous counterparts as demonstrated in the last census. This research will assist in innovative policy development including the creation of a culturally-sensitive model to assist Indigenous communities to raise their use of c ....Adoption and Effective Use of Information Communication Technologies in Indigenous Communities in Australia. This project on Indigenous use of the internet aims to identify the reasons why Indigenous Australians are 69% less likely to access the Internet than their non-Indigenous counterparts as demonstrated in the last census. This research will assist in innovative policy development including the creation of a culturally-sensitive model to assist Indigenous communities to raise their use of computers and the internet. Ultimately the aim of the research is to provide mechanisms to engage Indigenous people with current technology to advance health, education and housing outcomes in their communities. Read moreRead less
Predicting cell wall mechanics from structure in a materials engineering approach to plant growth. The project fosters a novel, interdisciplinary approach to understanding how the structure of plant cell walls determines their mechanical properties. Such understanding requires combining biological and engineering approaches and will illuminate how plants grow and produce cells and organs with particular shapes. This is scientifically important but is also important for industries depending on sp ....Predicting cell wall mechanics from structure in a materials engineering approach to plant growth. The project fosters a novel, interdisciplinary approach to understanding how the structure of plant cell walls determines their mechanical properties. Such understanding requires combining biological and engineering approaches and will illuminate how plants grow and produce cells and organs with particular shapes. This is scientifically important but is also important for industries depending on specialised cell shapes such as those of cotton and wood fibres. Our work will improve our understanding of how wall structure determines fibre and other cell shapes and give us tools which can be used to understand how final wall structure determines the fibre mechanics on which industrial users depend. Read moreRead less
Learning from the development and implementation of Australia's National Indigenous Forestry Strategy. The project will undertake a multi-disciplinary study of the National Indigenous Forest Strategy (NIFS) in the native title era. A team comprising three academics from the ANU and key industry partners will collaborate with a very experienced APAI on the project. There has been considerable public policy concern and debate about the development problems facing Indigenous communities, particular ....Learning from the development and implementation of Australia's National Indigenous Forestry Strategy. The project will undertake a multi-disciplinary study of the National Indigenous Forest Strategy (NIFS) in the native title era. A team comprising three academics from the ANU and key industry partners will collaborate with a very experienced APAI on the project. There has been considerable public policy concern and debate about the development problems facing Indigenous communities, particularly in regional and remote Australia. Forestry offers one option for economic initiative, especially on the significant Indigenous estate. This project will inform and monitor the evolving NIFS and canvass options for policy-realistic and culturally-acceptable ways that forestry can ameliorate Indigenous socio-economic disadvantage.Read moreRead less