Reducing skeletal malformations in cultured marine fish using gene expression, improved nutrition and advanced system operation. Reducing malformations in farmed fish will benefit the Australian economy and society by providing greater quantities of cheaper, higher quality fish. Increased farmed fish production, currently worth ~$300 million p.a., will increase exports and decrease imports (currently ~50% of all Australian consumed fish). To benefit are the important regional farming operations ....Reducing skeletal malformations in cultured marine fish using gene expression, improved nutrition and advanced system operation. Reducing malformations in farmed fish will benefit the Australian economy and society by providing greater quantities of cheaper, higher quality fish. Increased farmed fish production, currently worth ~$300 million p.a., will increase exports and decrease imports (currently ~50% of all Australian consumed fish). To benefit are the important regional farming operations in QLD, NSW, SA, NT, TAS and WA. In particular, the largest industry in Tasmania will profit by having a viable new species to farm (striped trumpeter) reducing risk due to climate change and global oversupply of salmon. Another important benefactor will be the rapidly expanding yellowtail kingfish industry. Read moreRead less
The link between environmental stress and disease onset in prawn aquaculture. The federal government has set a target for prawn aquaculture production to increase fourfold by 2010. A major barrier is disease: losses of 20% of production to viral diseases are not uncommon. To be internationally competitive, Australia needs to develop high health production systems. Most prawn stock carry chronic viral infections, but only exhibit disease symptoms following environmental stress. This project will ....The link between environmental stress and disease onset in prawn aquaculture. The federal government has set a target for prawn aquaculture production to increase fourfold by 2010. A major barrier is disease: losses of 20% of production to viral diseases are not uncommon. To be internationally competitive, Australia needs to develop high health production systems. Most prawn stock carry chronic viral infections, but only exhibit disease symptoms following environmental stress. This project will identify environmental stressors that activate viral disease in Penaeus monodon. Outcomes will be incorporated into on-farm managerial regimes to minimize risk of crop loss to disease. Development of biomarkers as indicators of stress related risks may be commercialized.Read moreRead less
Toward novel approaches for the control of parasitic nematodes via genomics/phenomics. The control of economically important parasitic worms of livestock relies heavily on the use of chemical compounds (anthelmintics). Their excessive and uncontrolled use has led to serious anthelmintic resistance problems in parasites, so that many treatments are no longer effective, and also to residue problems in meat, milk and the environment. We will use 'cutting edge' technologies to provide unique insight ....Toward novel approaches for the control of parasitic nematodes via genomics/phenomics. The control of economically important parasitic worms of livestock relies heavily on the use of chemical compounds (anthelmintics). Their excessive and uncontrolled use has led to serious anthelmintic resistance problems in parasites, so that many treatments are no longer effective, and also to residue problems in meat, milk and the environment. We will use 'cutting edge' technologies to provide unique insights into the molecular processes of parasite growth and reproduction, to develop safe and sustainable intervention strategies for parasites. The project will provide a unique technology platform and a skills base in parasite genomics and will generate significant intellectual property.Read moreRead less
Optimising barramundi production through early prediction of thermal tolerance and growth. Aquaculture is Australia's fastest growing primary industry and is increasingly becoming an important employer in regional Australia. Consequently, positive growth in this sector linked to productivity gains through R&D will result in improved socioeconomic prosperity of regional communities. This project will allow barramundi farmers to identify highly productive families early on in the culture process, ....Optimising barramundi production through early prediction of thermal tolerance and growth. Aquaculture is Australia's fastest growing primary industry and is increasingly becoming an important employer in regional Australia. Consequently, positive growth in this sector linked to productivity gains through R&D will result in improved socioeconomic prosperity of regional communities. This project will allow barramundi farmers to identify highly productive families early on in the culture process, thereby improving their efficiency of farming and increasing their international competitiveness in the rapidly expanding global market. The project will also establish Australia at the forefront of biotechnological research and its applications to aquaculture.Read moreRead less
The role of neurohormones in the regulation of appetite and successful sea water transfer in farmed Atlantic salmon. Cultured Atlantic salmon spend the first part of their life in freshwater and then following a physiological adaption phase called smoltification, the fish (now termed smolts) are transferred to sea cages for growout. A proportion of smolts fail to thrive after transfer, show slow or no growth and usually die some months later. This project will investigate the role that the neuro ....The role of neurohormones in the regulation of appetite and successful sea water transfer in farmed Atlantic salmon. Cultured Atlantic salmon spend the first part of their life in freshwater and then following a physiological adaption phase called smoltification, the fish (now termed smolts) are transferred to sea cages for growout. A proportion of smolts fail to thrive after transfer, show slow or no growth and usually die some months later. This project will investigate the role that the neurohomones that control both appetite and physiological stress in fish have in stimulating the resumption of feeding after sea water transfer.The basic knowledge generated will be used directly in development of strategies for minimising smolt failure in Atlantic salmon aquaculture.Read moreRead less
Improving vaccine performance through understanding host-pathogen interaction in yersiniosis. This project will significantly contribute to the economic and environmental sustainability of the Australian salmon industry. It will reduce salmon production costs, ensure sufficient supply of fish from hatchery to grow-out and reduce the use of antibiotics. Reduced use of antibiotics will benefit both the environment and human health. As the salmon industry is based in regional and rural areas, th ....Improving vaccine performance through understanding host-pathogen interaction in yersiniosis. This project will significantly contribute to the economic and environmental sustainability of the Australian salmon industry. It will reduce salmon production costs, ensure sufficient supply of fish from hatchery to grow-out and reduce the use of antibiotics. Reduced use of antibiotics will benefit both the environment and human health. As the salmon industry is based in regional and rural areas, this project will support rural and regional communities. This project will further strengthen Australian leadership in aquaculture research through use of molecular methods to address industry issues and will therefore increase the competitiveness of Australian science.Read moreRead less
Aquaculture of the tropical abalone: identifying and selecting for factors promoting high settlement, survival and growth. There is a growing demand worldwide for the 'cocktail'-sized tropical abalone Haliotis asinina. We have developed a full set of hatchery and grow-out procedures that Queensland Sea Scallops Pty Ltd will test on a commercial scale. At QSS, we will propagate and growout Haliotis asinina to determine the factors controlling settlement, survival, growth and health. We will do ....Aquaculture of the tropical abalone: identifying and selecting for factors promoting high settlement, survival and growth. There is a growing demand worldwide for the 'cocktail'-sized tropical abalone Haliotis asinina. We have developed a full set of hatchery and grow-out procedures that Queensland Sea Scallops Pty Ltd will test on a commercial scale. At QSS, we will propagate and growout Haliotis asinina to determine the factors controlling settlement, survival, growth and health. We will do this by combining breeding experiments with microarray gene profiling and other advanced gene expression studies. This knowledge will enhance the development of this new aquaculture industry in tropical Australia and our understanding of abalone aquaculture in general.Read moreRead less
The cellular basis of temperature impairment of reproductive function in Atlantic salmon. Elevated summer and autumn temperatures, either as a result of normal climate variation or global warming, inhibit reproduction in salmonid fishes by disrupting endocrine (hormonal processes). The mechanisms involved are unclear but are known to involve inhibition of ovarian estrogen and the assembly of egg-yolk proteins. This project will investigate the cellular basis of the inhibitory effect of high temp ....The cellular basis of temperature impairment of reproductive function in Atlantic salmon. Elevated summer and autumn temperatures, either as a result of normal climate variation or global warming, inhibit reproduction in salmonid fishes by disrupting endocrine (hormonal processes). The mechanisms involved are unclear but are known to involve inhibition of ovarian estrogen and the assembly of egg-yolk proteins. This project will investigate the cellular basis of the inhibitory effect of high temperature on reproduction, at the ovarian and hepatic levels. The understanding developed will be an essential component of amelioration strategies for managing the continued successful rearing of salmon and trout under warming environmental conditions.Read moreRead less
Practical application of gene silencing: is delivery of long double stranded ribonucleic acid (dsRNA) by plant cells efficient in conferring host resistance to parasitic nematodes? Nematode that attack plants cause $120 billion of crop losses worldwide. Chemicals used for their control are being phased out because of environmental concerns, and natural resistance is limited. The aim of this project is to use Australian IP to develop a new form of resistance to nematodes based on knowledge of th ....Practical application of gene silencing: is delivery of long double stranded ribonucleic acid (dsRNA) by plant cells efficient in conferring host resistance to parasitic nematodes? Nematode that attack plants cause $120 billion of crop losses worldwide. Chemicals used for their control are being phased out because of environmental concerns, and natural resistance is limited. The aim of this project is to use Australian IP to develop a new form of resistance to nematodes based on knowledge of the host-pathogen interactions. A successful outcome could contribute an additional 5-20% increase in crop yields (depending on the crop) through inherent resistance of crops to nematode pests. This would benefit rural communities and the national economy, and could also generate international royalties.Read moreRead less
Gene Expression Profiling and de novo Transcriptome Sequencing using Geneballs. The purpose of the project is to demonstrate that bead-based technology can be used in applications that currently require DNA hybridisation in order to overcome existing deficiencies in microarray technology. By providing the capability to quickly and efficiently produce, screen and utilize biomolecule libraries of nearly unlimited size, this technology provides the key to unlock the power of genomics and proteomics ....Gene Expression Profiling and de novo Transcriptome Sequencing using Geneballs. The purpose of the project is to demonstrate that bead-based technology can be used in applications that currently require DNA hybridisation in order to overcome existing deficiencies in microarray technology. By providing the capability to quickly and efficiently produce, screen and utilize biomolecule libraries of nearly unlimited size, this technology provides the key to unlock the power of genomics and proteomics for use in real world applications. The project has two aspects. First, relatively small directed cDNA-bead libraries will be compared to known low-density cDNA microarrays to validate the technique for utility in gene expression profiling. Secondly, large libraries containing short oligonucleotide sequences will be used for de novo sequencing of a complete transcriptome. Proof-of-concept in either case will pave the way for many genomic applications and catapult the technology to 'blockbuster' status.Read moreRead less