The link between environmental stress and disease onset in prawn aquaculture. The federal government has set a target for prawn aquaculture production to increase fourfold by 2010. A major barrier is disease: losses of 20% of production to viral diseases are not uncommon. To be internationally competitive, Australia needs to develop high health production systems. Most prawn stock carry chronic viral infections, but only exhibit disease symptoms following environmental stress. This project will ....The link between environmental stress and disease onset in prawn aquaculture. The federal government has set a target for prawn aquaculture production to increase fourfold by 2010. A major barrier is disease: losses of 20% of production to viral diseases are not uncommon. To be internationally competitive, Australia needs to develop high health production systems. Most prawn stock carry chronic viral infections, but only exhibit disease symptoms following environmental stress. This project will identify environmental stressors that activate viral disease in Penaeus monodon. Outcomes will be incorporated into on-farm managerial regimes to minimize risk of crop loss to disease. Development of biomarkers as indicators of stress related risks may be commercialized.Read moreRead less
Aquaculture of the tropical abalone: identifying and selecting for factors promoting high settlement, survival and growth. There is a growing demand worldwide for the 'cocktail'-sized tropical abalone Haliotis asinina. We have developed a full set of hatchery and grow-out procedures that Queensland Sea Scallops Pty Ltd will test on a commercial scale. At QSS, we will propagate and growout Haliotis asinina to determine the factors controlling settlement, survival, growth and health. We will do ....Aquaculture of the tropical abalone: identifying and selecting for factors promoting high settlement, survival and growth. There is a growing demand worldwide for the 'cocktail'-sized tropical abalone Haliotis asinina. We have developed a full set of hatchery and grow-out procedures that Queensland Sea Scallops Pty Ltd will test on a commercial scale. At QSS, we will propagate and growout Haliotis asinina to determine the factors controlling settlement, survival, growth and health. We will do this by combining breeding experiments with microarray gene profiling and other advanced gene expression studies. This knowledge will enhance the development of this new aquaculture industry in tropical Australia and our understanding of abalone aquaculture in general.Read moreRead less
Origin of multicellularity in animals: identification and analysis of intercellular signalling pathways in a basal metazoan, the demosponge Reniera. The Reniera genome project is a multi-million dollar collaboration between JGI (US-DOE) and Australian scientists that will see the sequencing of the first Australian marine animal by 2006. This project will significantly advance our understanding of the origins of animals and contribute to the reconstruction of creatures that lived over 600 million ....Origin of multicellularity in animals: identification and analysis of intercellular signalling pathways in a basal metazoan, the demosponge Reniera. The Reniera genome project is a multi-million dollar collaboration between JGI (US-DOE) and Australian scientists that will see the sequencing of the first Australian marine animal by 2006. This project will significantly advance our understanding of the origins of animals and contribute to the reconstruction of creatures that lived over 600 million years ago. A major outcome of this reconstruction will be a fundamental understanding of how cells communicate with each other during the process of development to give rise to the diversity of cell types within multicellular animals. This study will also shed light on what happens when cell communication goes astray, as observed in a range of human malignancies, including cancer. Read moreRead less
The sponge genome project and the evolution of multicellularity: using comparative genomics and developmental biology to reconstruct the first animals. Recently the entire genome from a living fossil - a sponge from the Great Barrier Reef - was sequenced (jointly supported by the ARC and US Department of Energy). As this genome is assembled and analysed, many of the fundamental biological processes that underlie the construction and evolution of all animals, including humans, will be revealed. ....The sponge genome project and the evolution of multicellularity: using comparative genomics and developmental biology to reconstruct the first animals. Recently the entire genome from a living fossil - a sponge from the Great Barrier Reef - was sequenced (jointly supported by the ARC and US Department of Energy). As this genome is assembled and analysed, many of the fundamental biological processes that underlie the construction and evolution of all animals, including humans, will be revealed. In addition, sponge genomics will fuel innovations in medicine and biotechnology. Specifically, sponges are renowned for their capacity to synthesise bioactive compounds used in drug development, and high-grade silica used for semi-conductor construction. This project will identify the gene networks controlling these biosynthetic processes.Read moreRead less
Variation in larval gene expression in a marine invertebrate: implications for population divergence via differential settlement response. Evolutionary and ecological functional genomics is an emerging field that integrates gene profiling technologies with experimental and field approaches of ecology and evolution. I take this approach to address a key problem in marine invertebrate biology: how do larvae respond to their environment and how does variation in this response influence the distribu ....Variation in larval gene expression in a marine invertebrate: implications for population divergence via differential settlement response. Evolutionary and ecological functional genomics is an emerging field that integrates gene profiling technologies with experimental and field approaches of ecology and evolution. I take this approach to address a key problem in marine invertebrate biology: how do larvae respond to their environment and how does variation in this response influence the distribution and evolution of a species? I will use a marine gastropod (abalone) model, for which there exists substantial development and population genetic data, and established aquaculture methodologies. Outcomes of this study will enhance knowledge of the stock structure of this and other commercial fisheries, as well as aquaculture efficiency.Read moreRead less
Translating genomic discoveries into improved commercial outcomes for the South Sea pearl industry. The purpose of this project is to understand the relationship between gene expression and pearl quality. By identifying the relationship between genes and pearls this project will determine the best conditions to grow selected pearl oyster stocks for the Australian South Sea pearl industry.
Cross-kingdom communications via small non-coding RNAs. This project aims to determine the role of small non-coding RNAs in mosquito-Wolbachia interactions, including Wolbachia microRNAs, concentrating on exchanged microRNAs between the two organisms and explore microRNAs effect on Wolbachia maintenance and its anti-viral property. Small non-coding RNAs play significant roles in various biological processes, including host-microorganism interactions. Recent evidence suggests that small RNAs can ....Cross-kingdom communications via small non-coding RNAs. This project aims to determine the role of small non-coding RNAs in mosquito-Wolbachia interactions, including Wolbachia microRNAs, concentrating on exchanged microRNAs between the two organisms and explore microRNAs effect on Wolbachia maintenance and its anti-viral property. Small non-coding RNAs play significant roles in various biological processes, including host-microorganism interactions. Recent evidence suggests that small RNAs can be exchanged between microorganisms and their hosts and regulate gene expression in the other organism. The endosymbiotic bacterium, Wolbachia, has attracted worldwide attention due to inhibiting replication of various vector-borne pathogens in mosquito vectors.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101089
Funder
Australian Research Council
Funding Amount
$371,800.00
Summary
Understanding masculinity, the crustacean way. The androgenic gland is responsible for maleness in crustaceans. This project will characterise the genes that control the masculinisation process in crustaceans, discovering new targets for sex reversal and sterility induction. These findings will have implications for aquaculture and the development of innovative tools for invasive/pest crustacean control.
Sleeping snails: investigating hypometabolism to reveal critical factors that aid life extension. The apparent state of eternal dormancy has fascinated people for hundreds of years. This project will explore new frontiers in life extension and snail control by defining those genes and peptides involved in snail hypometabolism. To achieve this, the project will interrogate the snails' natural state of hypometabolism called estivation.