An MRI Study Of Emotional Processing Deficits In Childhood
Funder
National Health and Medical Research Council
Funding Amount
$578,985.00
Summary
The ability to recognise and process emotions in other people is fundamental to healthy social interactions. Conduct disordered children with callous and unemotional traits have difficulty recognizing fearful expressions, possibly due to lack of attention to cues such as facial expressions that healthy people naturally attend to. This study will use neuroimaging to determine if brain activity changes to look more like typically developing children if their gaze is redirected to facial cues of em ....The ability to recognise and process emotions in other people is fundamental to healthy social interactions. Conduct disordered children with callous and unemotional traits have difficulty recognizing fearful expressions, possibly due to lack of attention to cues such as facial expressions that healthy people naturally attend to. This study will use neuroimaging to determine if brain activity changes to look more like typically developing children if their gaze is redirected to facial cues of emotion.Read moreRead less
From Brain Maps To Mechanisms: Modeling The Pathophysiology Of Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$320,891.00
Summary
My Fellowship will develop a framework that integrates brain imaging data with mathematical models of the brain to help understand the mechanisms responsible for schizophrenia. By linking functional Magnetic Resonance Imaging (fMRI) measurements to models of their underlying causes, the work may lead to new treatments that target the specific dysfunction in individuals with this debilitating brain disorder.
Optimising Radiation Therapy Delivery For Cancer Patients Using Daily Image Guidance To Maximize Cure And Reduce Normal Tissue Side Effects
Funder
National Health and Medical Research Council
Funding Amount
$510,968.00
Summary
When using radiotherapy to kill tumours, the radiation beams need to be targeted at the tumour, plus a margin of error around it to ensure that it receives sufficient dose despite uncertainties in its exact location relative to reference points used for beam alignment. Advanced statistical modelling techniques applied to data collected from patients will be used to determine the optimal margin width for individual patients to maximise cancer cure while minimising normal tissue side effects.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100092
Funder
Australian Research Council
Funding Amount
$1,100,000.00
Summary
Quantum microscopy facility for ultrasensitive nanoscale magnetic imaging. Investigations of 2D and van der Waals materials, biological samples, energy materials, and quantum devices on the nano- and microscale are revolutionising medicine, communications, information technology, energy production and storage by virtue of new phenomena. The new quantum microscopy facility will enable state-of-the-art capabilities in mapping chemical, magnetic, optical, electronic, and spectral properties, provid ....Quantum microscopy facility for ultrasensitive nanoscale magnetic imaging. Investigations of 2D and van der Waals materials, biological samples, energy materials, and quantum devices on the nano- and microscale are revolutionising medicine, communications, information technology, energy production and storage by virtue of new phenomena. The new quantum microscopy facility will enable state-of-the-art capabilities in mapping chemical, magnetic, optical, electronic, and spectral properties, providing cutting-edge tools that will enable breakthroughs in both existing and future multi-disciplinary projects in photonics, quantum devices, nanomaterials, nanoelectronics, biotechnology, and energy technology as key drivers of the new economy in Australia.Read moreRead less
Low Cost High Precision Radiotherapy: A Synergistic Framework For Tumour Tracking During Treatment
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Advances in technology have enabled radiotherapy to become more sophisticated and more efficient at treating cancer. Yet, despite its sophistication, today radiotherapy suffers from a major problem: whilst we routinely image patients prior to treatment, no anatomical information is available during treatment. This project aims to solve this problem by making use of a number of sensors that are already available in a radiotherapy to track the tumours positions during treatment, when it counts.
Precision Nanomedicine-based Diagnostics And Therapeutics For Refractory Malignancies
Funder
National Health and Medical Research Council
Funding Amount
$7,329,484.00
Summary
The vast majority of cancer patients die of their disease due to the emergence of drug resistant cancer cells or metastatic disease that is diagnosed at late stages. Our program aims to develop new types of therapy to specifically target aggressive cancers. To detect cancer early and evaluate the effectiveness of cancer therapy, we will develop sensitive diagnostic tools and devices. This research has application to both childhood and adult cancers.