Genomic Analysis Of DNA Binding And Gene Regulation By The Chromatin Remodelling Factor UBF
Funder
National Health and Medical Research Council
Funding Amount
$624,254.00
Summary
Synthesis of ribosomes, the cellular protein synthetic machinery, is the major anabolic event of a growing cell and is frequently dysregulated during disease such as cancer. This grant will examine a protein termed UBF that we think plays an important role in orchestrating the cellular response to dysregulated ribosome biogenesis. By understanding how UBF functions we hope to uncover novel therapeutic approaches to treat diseases associated with ribosome stress .
Preparing Australia For Genomic Medicine: A Proposal By The Australian Genomics Health Alliance
Funder
National Health and Medical Research Council
Funding Amount
$25,000,000.00
Summary
The sequencing of the human genome brings the possibility of more accurate identification of the underlying basis of many diseases. This technology has moved so rapidly, however, that clinical access has been limited. In this application, a national alliance of clinicians, researchers, health economists and policymakers will evaluate the case for clinical genomics across inherited disease and cancer, determine how best to deliver this to the patient and train a capable workforce.
Special Research Initiatives - Grant ID: SR0354466
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Mathematics in Contemporary Science. The Mathematics in Contemporary Science Research Network brings contemporary methods of non-linear analysis and differential equations, geometric reasoning and relevant algebraic and topological ideas to enrich six application areas in modern science: Complex Systems, Computer Vision, Optimal Transportation, Nanotechnology, Physics and Shortest Networks. MiCS will develop both the mathematics and the application areas in parallel. It will focus on postgradu ....Mathematics in Contemporary Science. The Mathematics in Contemporary Science Research Network brings contemporary methods of non-linear analysis and differential equations, geometric reasoning and relevant algebraic and topological ideas to enrich six application areas in modern science: Complex Systems, Computer Vision, Optimal Transportation, Nanotechnology, Physics and Shortest Networks. MiCS will develop both the mathematics and the application areas in parallel. It will focus on postgraduate training through workshops, summer schools and web based resources and build long-term international collaborations with EU networks and NSERC, NSF and EPSRC institutes as well as bringing together academic and industry leaders.Read moreRead less
Operator algebras as models for dynamics and geometry. Operator algebra is the mathematical theory which describes quantum physics and predicts how quantum systems will behave. Through this project, the researcher's recent discoveries in operator algebra will give us new insight into the dynamics and geometry - that is, the behaviour and shape - of the quantum world.
Core-scale geodynamic rock-typing of reservoir rock. This project aims to develop a robust classification method for reservoir rock incorporating static, dynamic and mechanical attributes via multiscale digital core analysis using the concept of regional measures. Rock-types are used to populate reservoir models in a sophisticated routine of geological classification, spatial modelling and uncertainty analysis. Introducing high-resolution rock-types incorporating hydraulic properties and compact ....Core-scale geodynamic rock-typing of reservoir rock. This project aims to develop a robust classification method for reservoir rock incorporating static, dynamic and mechanical attributes via multiscale digital core analysis using the concept of regional measures. Rock-types are used to populate reservoir models in a sophisticated routine of geological classification, spatial modelling and uncertainty analysis. Introducing high-resolution rock-types incorporating hydraulic properties and compaction allows the development of a new generation of reservoir simulators. The project aims to derive a consistent high-resolution definition of rock-types incorporating compaction for petrophysical, geological and reservoir engineering purposes. This would greatly enhance our capacity to develop thinly layered reservoirs with direct applications in 4-D seismic reservoir characterisation and the development of unconventional reservoirs.Read moreRead less
Modular Index Theory. This project capitilises on Australian advances in mathematics, particularly noncommutative geometry. It will maintain and extend Australia's prominence in this subject, providing excellent opportunities for young researchers via the research networks this project will establish. Being at the interface of ideas in mathematics and physics, there is potential for future technological spin offs for Australia.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100177
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Advanced electron paramagnetic resonance (EPR) facilities for chemical, biological and materials sciences. New instrumentation to advance national research in hydrogen fuel generation from renewable sources, new generation photo-voltaic technologies, novel polymer and other chemical materials and advanced computing systems will be provided by this project. A new high sensitivity electron paramagnetic resonance facility, located at the Australian National University, will serve researchers in the ....Advanced electron paramagnetic resonance (EPR) facilities for chemical, biological and materials sciences. New instrumentation to advance national research in hydrogen fuel generation from renewable sources, new generation photo-voltaic technologies, novel polymer and other chemical materials and advanced computing systems will be provided by this project. A new high sensitivity electron paramagnetic resonance facility, located at the Australian National University, will serve researchers in the ACT region devoted to the broad range of activities summarised above. A particular focus involves novel, biologically inspired energy systems and high efficiency solar cell technology.Read moreRead less
Improving access to phylogenomic resources for under-resourced species: a new look at existing tools. This project will have an impact on our understanding of how to most effectively use existing genomic resources to benefit a wider range of species and to better design new genomic resources. By doing so, improved access to genomic resources will be provided to species that currently have few options.