Novel genomic technologies to improve fertility in northern beef cattle. This project aims to develop new genomic technologies to enable accelerated improvement of cow fertility. Increased global demand for beef is driving northern Australian beef enterprises to develop innovative ways to increase productivity. A substantial industry challenge is poor fertility of cows, with weaning rates frequently less than 40%. The expected outcomes of this project are an improvement in weaning rates to enabl ....Novel genomic technologies to improve fertility in northern beef cattle. This project aims to develop new genomic technologies to enable accelerated improvement of cow fertility. Increased global demand for beef is driving northern Australian beef enterprises to develop innovative ways to increase productivity. A substantial industry challenge is poor fertility of cows, with weaning rates frequently less than 40%. The expected outcomes of this project are an improvement in weaning rates to enable accelerated genetic gain for fertility in these enterprises by delivering a low cost array, which assays thousands of DNA variants affecting fertility simultaneously. This should provide significant benefits such as a new genomic prediction method informed by gene expression data from a unique resource of Brahman cattle with exceptionally high fertility, generating significant industry benefits.Read moreRead less
Cellular genomic approach to the pathogenesis of multiple sclerosis. This project compares the levels of gene usage in two important immune cell types between patients with multiple sclerosis and people who do not have the disease. It aims to identify the molecular basis for the disease, in order to identify new diagnostic, preventative and treatment options.
Catalytic production of health food additives from crustacean wastes. Cost-effective production of new synthetic amino acids as value-added food additives from crustacean wastes is vital for waste recycling and a sustainable economy. This project will develop a unique catalytic system for the selective conversion of waste-derived compounds into tailor-made products. Advanced in situ spectroscopic techniques will be employed to establish the structure-reactivity relationship of working catalysts ....Catalytic production of health food additives from crustacean wastes. Cost-effective production of new synthetic amino acids as value-added food additives from crustacean wastes is vital for waste recycling and a sustainable economy. This project will develop a unique catalytic system for the selective conversion of waste-derived compounds into tailor-made products. Advanced in situ spectroscopic techniques will be employed to establish the structure-reactivity relationship of working catalysts and thereby manipulate the key factors governing the activity/selectivity. Such cutting-edge knowledge gained is crucial for optimising process effciency and resource utilisation, which is essential for the success of the biorefining industry and a more environmentally-friendly chemical and food economy in Australia.Read moreRead less
Smarter fermentations through starter culture genomics. Australia makes over $1 billion dollars worth of cheese each year, however fermentation can be adversely affected by virus (phage) attack or sub-optimal strain mixtures. The latest genomics and molecular biology approaches will be used to characterise and optimise starter culture strains leading to improved flavour, quality and efficiency in cheese making.
Thermoelectric devices for high-performing localised coolers. This project aims to develop a lightweight, low-energy-consumption, and high-durability wearable thermoelectric cooler for localised cooling using a novel industry-led approach, coupled with device design and materials engineering strategies. The key breakthrough expected is to design wearable thermoelectric coolers by using flexible substrates and thermoelectric materials with engineered chemistry and unique structures for achieving ....Thermoelectric devices for high-performing localised coolers. This project aims to develop a lightweight, low-energy-consumption, and high-durability wearable thermoelectric cooler for localised cooling using a novel industry-led approach, coupled with device design and materials engineering strategies. The key breakthrough expected is to design wearable thermoelectric coolers by using flexible substrates and thermoelectric materials with engineered chemistry and unique structures for achieving localised, instant, and controllable cooling with super low power input for personal usage in building and mining industry. Expected outcomes include innovative technologies for achieving high-efficiency cooling, which will provide significant economic and commercial benefits for Australia.Read moreRead less
New high energy density cathode materials for lithium ion batteries. This project aims to develop new high-energy-density and low-cost lithium-rich cathode materials for advanced lithium-ion batteries that can store solar energy for Australian households and power the next generation electric vehicles. The project will design innovative strategies to suppress the voltage decay and capacity decline of the lithium rich materials over long-term cycling. The project expects to significantly improve ....New high energy density cathode materials for lithium ion batteries. This project aims to develop new high-energy-density and low-cost lithium-rich cathode materials for advanced lithium-ion batteries that can store solar energy for Australian households and power the next generation electric vehicles. The project will design innovative strategies to suppress the voltage decay and capacity decline of the lithium rich materials over long-term cycling. The project expects to significantly improve battery performance at a lower price and make a substantial impact to the energy supply technologies and industries in Australia and benefit the environment in the long run.Read moreRead less
Methods to infer dense genomic information from sparsely genotyped populations. Prediction of phenotype based on DNA polymorphisms or sequence has important applications such as prediction of disease risk in human medicine and prediction of genetic value in plant or animal breeding. This project will enhance precision and lower the cost of association studies leading to substantial increase in accuracy of such predictions. This will allow more effective genetic improvement, particularly of diff ....Methods to infer dense genomic information from sparsely genotyped populations. Prediction of phenotype based on DNA polymorphisms or sequence has important applications such as prediction of disease risk in human medicine and prediction of genetic value in plant or animal breeding. This project will enhance precision and lower the cost of association studies leading to substantial increase in accuracy of such predictions. This will allow more effective genetic improvement, particularly of difficult but important traits such as disease resistance, reduced green-house gas emissions and product quality. The same methods can be extended to improve genetic improvement in plants and better prediction of human disease risk. Read moreRead less
Improving academic outcomes by moderating anxiety in children with autism. The project aims to investigate links between anxiety and academic enablers for children with autism. As a group, these children are currently achieving at lower rates than their peers, with implications for their future social and economic wellbeing. Effective interventions to improve educational outcomes are lacking. This project will investigate how anxiety, a commonly occurring condition in autism, impacts attitudes a ....Improving academic outcomes by moderating anxiety in children with autism. The project aims to investigate links between anxiety and academic enablers for children with autism. As a group, these children are currently achieving at lower rates than their peers, with implications for their future social and economic wellbeing. Effective interventions to improve educational outcomes are lacking. This project will investigate how anxiety, a commonly occurring condition in autism, impacts attitudes and behaviours that facilitate students’ participation in and ability to benefit from academic instruction in the classroom. Findings are intended to provide an evidence base for the development of an intervention suitable for use by service providers to increase academic achievement in children with autism.Read moreRead less
Interfacial and Structural Changes During Digestion of Milk-like Systems. This project aims to enhance the understanding of the behaviour of milk and milk-like systems during digestion. Utilising new Australian research infrastructure the project aims to unlock the complex behaviour across different types of milk (including human breast milk) and infant formulae, linking how enzymes behave towards fat droplets and the consequences for lipid structuring and nutrient transport. The rational design ....Interfacial and Structural Changes During Digestion of Milk-like Systems. This project aims to enhance the understanding of the behaviour of milk and milk-like systems during digestion. Utilising new Australian research infrastructure the project aims to unlock the complex behaviour across different types of milk (including human breast milk) and infant formulae, linking how enzymes behave towards fat droplets and the consequences for lipid structuring and nutrient transport. The rational design of systems that function much more closely to human milk will enable the development of new products with flow on benefits in human nutrition and increased utilisation of products from our dairy industry.Read moreRead less
Sustainable Hydrogen Production from Used Water. The project aims to address the pressing challenge of water scarcity in hydrogen production by developing an innovative approach of using used water as the feed for water electrolysis. The project will result in an in-depth understanding of the impacts of water impurities in used water on the performance and durability of water electrolysers, and develop guidelines for the design of highly durable water electrolysers and the operation and upgrade ....Sustainable Hydrogen Production from Used Water. The project aims to address the pressing challenge of water scarcity in hydrogen production by developing an innovative approach of using used water as the feed for water electrolysis. The project will result in an in-depth understanding of the impacts of water impurities in used water on the performance and durability of water electrolysers, and develop guidelines for the design of highly durable water electrolysers and the operation and upgrade of existing wastewater treatment plants. The project will advance the practical applications of water electrolysis for scalable and sustainable hydrogen production and help Australia secure a leading position in the global emerging hydrogen economy.Read moreRead less