Identifying Target Genes For Novel Anti-epileptic Therapies In The Mouse
Funder
National Health and Medical Research Council
Funding Amount
$469,802.00
Summary
Epilepsy is a disease which affects 2-4% of the population. There are a wide range of drugs available to treat the condition but there is consistently 30-40% of patients who do not respond well to any of these drugs and who continue to have seizures. The reason that there are no drugs available for these people is that most of the drugs available have been designed along the same principles. A new set of principles is needed to develop new drugs which will be able to treat those people not respo ....Epilepsy is a disease which affects 2-4% of the population. There are a wide range of drugs available to treat the condition but there is consistently 30-40% of patients who do not respond well to any of these drugs and who continue to have seizures. The reason that there are no drugs available for these people is that most of the drugs available have been designed along the same principles. A new set of principles is needed to develop new drugs which will be able to treat those people not responding to current therapy. This project is designed to identify new biologic pathways which may be interrupted with drugs to prevent seizures in people with epilepsy. This project uses a procedure to induce mutations into genes in mice and then screens for mice which do not seize when challenged with a drug which generates seizures in mice. Genetic studies will identify the mutated genes and these will be used as potential targets for new therapies or will identify new biological pathway which should expand the use of future anti-epileptic drugs.Read moreRead less
Special Research Initiatives - Grant ID: SR0354466
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Mathematics in Contemporary Science. The Mathematics in Contemporary Science Research Network brings contemporary methods of non-linear analysis and differential equations, geometric reasoning and relevant algebraic and topological ideas to enrich six application areas in modern science: Complex Systems, Computer Vision, Optimal Transportation, Nanotechnology, Physics and Shortest Networks. MiCS will develop both the mathematics and the application areas in parallel. It will focus on postgradu ....Mathematics in Contemporary Science. The Mathematics in Contemporary Science Research Network brings contemporary methods of non-linear analysis and differential equations, geometric reasoning and relevant algebraic and topological ideas to enrich six application areas in modern science: Complex Systems, Computer Vision, Optimal Transportation, Nanotechnology, Physics and Shortest Networks. MiCS will develop both the mathematics and the application areas in parallel. It will focus on postgraduate training through workshops, summer schools and web based resources and build long-term international collaborations with EU networks and NSERC, NSF and EPSRC institutes as well as bringing together academic and industry leaders.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100048
Funder
Australian Research Council
Funding Amount
$466,097.00
Summary
Ammonium-selective membranes to shift water industry into circular economy. The project aims to develop ammonium-selective membranes which are urgently needed in Australian key industries for sustainable ammonia recovery. The project expects to construct the membranes to achieve desirable pore size and surface functionality for fast and selective ammonia transport. The developed membranes should make ammonia recovery from wastewater more effective and sustainable, leading to the healthy waterway ....Ammonium-selective membranes to shift water industry into circular economy. The project aims to develop ammonium-selective membranes which are urgently needed in Australian key industries for sustainable ammonia recovery. The project expects to construct the membranes to achieve desirable pore size and surface functionality for fast and selective ammonia transport. The developed membranes should make ammonia recovery from wastewater more effective and sustainable, leading to the healthy waterway and reduced energy for both ammonia production and removal. Recovered ammonia expects to produce valuable products, supporting agriculture industry and hydrogen economy. The developed membranes should enable water industry's shift into circular economy, providing significant economic and environmental benefits to Australia.Read moreRead less
Sustainable Hydrogen Production from Used Water. The project aims to address the pressing challenge of water scarcity in hydrogen production by developing an innovative approach of using used water as the feed for water electrolysis. The project will result in an in-depth understanding of the impacts of water impurities in used water on the performance and durability of water electrolysers, and develop guidelines for the design of highly durable water electrolysers and the operation and upgrade ....Sustainable Hydrogen Production from Used Water. The project aims to address the pressing challenge of water scarcity in hydrogen production by developing an innovative approach of using used water as the feed for water electrolysis. The project will result in an in-depth understanding of the impacts of water impurities in used water on the performance and durability of water electrolysers, and develop guidelines for the design of highly durable water electrolysers and the operation and upgrade of existing wastewater treatment plants. The project will advance the practical applications of water electrolysis for scalable and sustainable hydrogen production and help Australia secure a leading position in the global emerging hydrogen economy.Read moreRead less
Using 3D printing to improve access to graphics by vision-impaired people. This project aims to investigate the possible benefits of 3D printing for production of accessible materials for vision-impaired people. Currently tactile graphics are used to provide severely vision-impaired adults and children with access to graphical content used in education and in orientation and mobility training. This project is expected to clarify the kinds of graphics for which 3D prints are better suited than ta ....Using 3D printing to improve access to graphics by vision-impaired people. This project aims to investigate the possible benefits of 3D printing for production of accessible materials for vision-impaired people. Currently tactile graphics are used to provide severely vision-impaired adults and children with access to graphical content used in education and in orientation and mobility training. This project is expected to clarify the kinds of graphics for which 3D prints are better suited than tactile graphics, and to build capacity within the national accessible format provision sector for the production and use of 3D prints. Benefits will include increased educational opportunities and quality of life for Australians with severe vision impairment, through improved access to graphic materials used in education and orientation and mobility training.
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Industrial Transformation Research Hubs - Grant ID: IH230100005
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub in Zero-emission Power Generation for Carbon Neutrality. This Hub aims to develop sustainable zero-emission power generation technologies to transform gaseous waste (mainly CO2) from our energy and manufacturing sectors into valuable products and create scalable pathways to market for driving industry transformation. This Hub expects to harvest renewable energy from the environment by using zero-emission power generators and then store it in green and safer batteries for convert ....ARC Research Hub in Zero-emission Power Generation for Carbon Neutrality. This Hub aims to develop sustainable zero-emission power generation technologies to transform gaseous waste (mainly CO2) from our energy and manufacturing sectors into valuable products and create scalable pathways to market for driving industry transformation. This Hub expects to harvest renewable energy from the environment by using zero-emission power generators and then store it in green and safer batteries for converting gaseous waste from sectors that cannot easily avoid emission into useful chemicals, which in turn realize carbon neutrality and negativity. The outcomes of this Hub are likely to be transformative for industry, the economy, and society in new-type renewable energy resources through decreasing environmental pollutants. Read moreRead less