The Influence Of Physical Activity And Sedentary Behaviour On Physical Function
Funder
National Health and Medical Research Council
Funding Amount
$1,269,867.00
Summary
Declines in physical function (e.g. stair climbing, bending/kneeling) can lead to a loss of personal independence. Physical activity can prevent or delay these declines, whereas a sedentary lifestyle can hasten them. This project examines the contribution of physical activity and sedentary behaviour to declines in physical function among baby boomers. Results will inform policy aimed at maintaining people’s independence and minimizing health care costs associated with an ageing population.
The Tasmanian Healthy Brain Project: A Longitudinal Intervention Study To Reduce The Risk Of Ageing-related Cognitive Decline And Dementia
Funder
National Health and Medical Research Council
Funding Amount
$878,792.00
Summary
It has been proposed that engagement in purposeful complex mental stimulation provides protection against dementia. The Tasmanian Healthy Brain Project (THBP) is a unique, large-scale prospective trial that examines whether university-level study in older adult population reduces ageing-related cognitive decline and risk of dementia. This project will also examine how an individual’s genetic profile may influence the potential benefits of complex mental stimulation as well as risk of dementia.
The Healthy Brain Project: A Prospective Cohort Study To Examine How Later-life University Education May Affect The Trajectory Of Ageing-related Cognitive Decline
Funder
National Health and Medical Research Council
Funding Amount
$1,085,742.00
Summary
Previous research has indicated that higher levels of education in early adulthood are associated with lower risk for dementia in older adults. This world-first project will examine if older adults who undertake university education have reduced rates of age-related cognitive decline than older adults who do not undertake further education. This would support the notion that boosting cognitive reserve in later life is protective against age- and disease-related neurodegenerative change.
Identifying Resistance Mechanisms Of Targeted BRAF Inhibitors In Metastatic Melanoma
Funder
National Health and Medical Research Council
Funding Amount
$379,015.00
Summary
Late-stage melanoma is an aggressive skin cancer for which traditional treatment strategies such as chemotherapy are ineffective. Recently, a new class of targeted drugs (BRAF inhibitors) has become the standard of care for a subset of melanoma patients; however, long term treatment success is complicated by drug resistance. This study will identify the causes of resistance with the purpose to improve targeted drug strategies and increase survival rates for late-stage melanoma patients.
New high energy density cathode materials for lithium ion batteries. This project aims to develop new high-energy-density and low-cost lithium-rich cathode materials for advanced lithium-ion batteries that can store solar energy for Australian households and power the next generation electric vehicles. The project will design innovative strategies to suppress the voltage decay and capacity decline of the lithium rich materials over long-term cycling. The project expects to significantly improve ....New high energy density cathode materials for lithium ion batteries. This project aims to develop new high-energy-density and low-cost lithium-rich cathode materials for advanced lithium-ion batteries that can store solar energy for Australian households and power the next generation electric vehicles. The project will design innovative strategies to suppress the voltage decay and capacity decline of the lithium rich materials over long-term cycling. The project expects to significantly improve battery performance at a lower price and make a substantial impact to the energy supply technologies and industries in Australia and benefit the environment in the long run.Read moreRead less
Neural Mechanisms Of Language Facilitation In Aphasia Due To Transcranial Direct Current Stimulation.
Funder
National Health and Medical Research Council
Funding Amount
$523,192.00
Summary
This project will assess the underlying neural mechanisms by which neurostimulation improves impaired language functions after stroke (aphasia). This will be accomplished by using a novel combination of functional magnetic resonance imaging and simultaneous transcranial direct current stimulation (tDCS) administered to different brain regions. These studies will provide crucial information necessary to optimise future clinical trials that combine tDCS with language therapy.
New hierarchical electrode design for high-power lithium ion batteries. This project aims to develop new types of hierarchical electrodes for high-rate lithium ion batteries with long cycling life. The key concepts are the development of multi-shelled hollow structured silicon-based anode and Li-rich layered oxides cathode to achieve both high power and energy density, and the adoption of graphene to further improve rate capability and cycling stability. Effective energy storage systems play an ....New hierarchical electrode design for high-power lithium ion batteries. This project aims to develop new types of hierarchical electrodes for high-rate lithium ion batteries with long cycling life. The key concepts are the development of multi-shelled hollow structured silicon-based anode and Li-rich layered oxides cathode to achieve both high power and energy density, and the adoption of graphene to further improve rate capability and cycling stability. Effective energy storage systems play an important role in the development of renewable energies and electric vehicles. The project outcomes will lead to innovative technologies in low carbon emission transportation and efficient energy storage systems.Read moreRead less
Engineered Polymer Scaffolds for Controlled Proliferation and Differentiation of Stem Cells. This project aims to develop a new methodology to sculpt 3D polymer scaffolds coated with cell adhesion and growth factors to control environmental cues, for the first time rapidly generating large quantities of undifferentiated stem cells. This project aims to exponentially increase cell generation in order to finally be able to unlock the potential of stem cells for application in regenerative medicine ....Engineered Polymer Scaffolds for Controlled Proliferation and Differentiation of Stem Cells. This project aims to develop a new methodology to sculpt 3D polymer scaffolds coated with cell adhesion and growth factors to control environmental cues, for the first time rapidly generating large quantities of undifferentiated stem cells. This project aims to exponentially increase cell generation in order to finally be able to unlock the potential of stem cells for application in regenerative medicine. The resulting cell repositories could make a significant contribution to human health outcomes.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100892
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Designing compressible hybrid supercapacitors from graphene aerogels. This project aims to develop high-performance compressible energy storage devices. Compressible hybrid supercapacitors are promising energy storage devices for elastic and wearable electronics under large strain and deformation. However, the controlled fabrication of such devices is challenging. This project aims to design and synthesise compressible hybrid supercapacitors using graphene aerogels as substrates through structur ....Designing compressible hybrid supercapacitors from graphene aerogels. This project aims to develop high-performance compressible energy storage devices. Compressible hybrid supercapacitors are promising energy storage devices for elastic and wearable electronics under large strain and deformation. However, the controlled fabrication of such devices is challenging. This project aims to design and synthesise compressible hybrid supercapacitors using graphene aerogels as substrates through structural design and surface modification. The success of the project will benefit Australia’s booming graphite industry and promote Australian competitiveness in wearable electronics markets.Read moreRead less