Identification Of Glaucoma Susceptibility Variants By Exome Sequencing In Extended Pedigrees Showing Prior Evidence Of Gene Segregation.
Funder
National Health and Medical Research Council
Funding Amount
$694,002.00
Summary
Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for tr ....Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for treatment or diagnosis.Read moreRead less
From The Synchrotron To The Clinic: Translation Of A Novel Functional Lung Imaging Technology
Funder
National Health and Medical Research Council
Funding Amount
$891,834.00
Summary
Our team has recently developed a synchrotron technology with a startling capacity for dynamic functional imaging that can act as a sensitive regional indicator of lung disease. We will demonstrate that this technology can be translated from the synchrotron to the lab and eventually the clinic. We will provide proof of this concept by the application of this technology to emphysema, asthma, lung cancer, cystic fibrosis lung disease and neonatal resuscitation.
ARC Centre of Excellence for Electromaterials Science. The ARC Centre of Excellence for Electromaterials Science (ACES) will create next generation electrochemical devices via the precision assembly of nano/micro dimensional components into macroscopic structures. Through the discovery of new materials and structures, and understanding how spatial arrangement in 3D influences chemical, physical and biological properties, ACES will define the cutting edge of Electromaterials Science. The resultin ....ARC Centre of Excellence for Electromaterials Science. The ARC Centre of Excellence for Electromaterials Science (ACES) will create next generation electrochemical devices via the precision assembly of nano/micro dimensional components into macroscopic structures. Through the discovery of new materials and structures, and understanding how spatial arrangement in 3D influences chemical, physical and biological properties, ACES will define the cutting edge of Electromaterials Science. The resulting technology breakthroughs will have a direct impact on some of today's most challenging global problems in clean energy, synthetic biosystems, diagnostics and soft robotics. National benefit to Australia will be realised through the creation of new manufacturing industries.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC140100026
Funder
Australian Research Council
Funding Amount
$2,997,000.00
Summary
ARC Training Centre for the Australian Food Processing Industry in the 21st Century. ARC Training Centre for the Australian Food Processing Industry in the 21st Century. The Training Centre will educate a new generation of engineers and scientists and foster the capacity of Australian food industries to further develop advanced technologies in manufacturing and product improvement. The key objective is to support industry production of nutraceuticals for the promotion of health and well-being. I ....ARC Training Centre for the Australian Food Processing Industry in the 21st Century. ARC Training Centre for the Australian Food Processing Industry in the 21st Century. The Training Centre will educate a new generation of engineers and scientists and foster the capacity of Australian food industries to further develop advanced technologies in manufacturing and product improvement. The key objective is to support industry production of nutraceuticals for the promotion of health and well-being. In enabling the production of these nutraceuticals the Training Centre will design cost effective and sustainable processes that minimise waste-products, enhance efficiency and minimize the energy consumption. These high value products have enormous potential globally to boost not only partner company revenues but to significantly increase Australian exports in agribusiness.Read moreRead less