Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100036
Funder
Australian Research Council
Funding Amount
$440,000.00
Summary
National in-situ transmission electron microscope facilities. This project will establish six complementary transmission electron microscope (TEM) facilities at various locations. The establishment of the facilities will be a key step in developing advanced capacity in Australia and will support ground-breaking research in diverse material systems for various high-performing applications, including electronics, optoelectronics, light metals, biomaterials, energy, and environment.
Engineered Polymer Scaffolds for Controlled Proliferation and Differentiation of Stem Cells. This project aims to develop a new methodology to sculpt 3D polymer scaffolds coated with cell adhesion and growth factors to control environmental cues, for the first time rapidly generating large quantities of undifferentiated stem cells. This project aims to exponentially increase cell generation in order to finally be able to unlock the potential of stem cells for application in regenerative medicine ....Engineered Polymer Scaffolds for Controlled Proliferation and Differentiation of Stem Cells. This project aims to develop a new methodology to sculpt 3D polymer scaffolds coated with cell adhesion and growth factors to control environmental cues, for the first time rapidly generating large quantities of undifferentiated stem cells. This project aims to exponentially increase cell generation in order to finally be able to unlock the potential of stem cells for application in regenerative medicine. The resulting cell repositories could make a significant contribution to human health outcomes.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100121
Funder
Australian Research Council
Funding Amount
$270,000.00
Summary
An integrated system for characterisation of mechanical behaviour of bio- and nanomaterials at micro and nano scales in Queensland. Australia's material sciences will benefit from a new integrated system capable of microforce and nanomechanical testing of biomaterials, polymers and thin films, medical devices and electronics at the micro and nano scales. This facility will support ground-breaking research. It will help promote strategic collaboration and ensure the competitiveness of related and ....An integrated system for characterisation of mechanical behaviour of bio- and nanomaterials at micro and nano scales in Queensland. Australia's material sciences will benefit from a new integrated system capable of microforce and nanomechanical testing of biomaterials, polymers and thin films, medical devices and electronics at the micro and nano scales. This facility will support ground-breaking research. It will help promote strategic collaboration and ensure the competitiveness of related and emerging industries.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100012
Funder
Australian Research Council
Funding Amount
$890,000.00
Summary
Dual Column-Focused Ion Beam/Scanning Electron Microscope facility for Queensland. Dual column focused ion beam/scanning electron microscope facility: This facility will precisely cut specimens and surfaces that can be imaged in a variety of ways, including crystallographic and elemental space, of particular use for physical scientists, as well as biological specimens. This instrument will provide information at resolutions between optical and transmission electron microscopy, images that will ....Dual Column-Focused Ion Beam/Scanning Electron Microscope facility for Queensland. Dual column focused ion beam/scanning electron microscope facility: This facility will precisely cut specimens and surfaces that can be imaged in a variety of ways, including crystallographic and elemental space, of particular use for physical scientists, as well as biological specimens. This instrument will provide information at resolutions between optical and transmission electron microscopy, images that will effectively provide the biologist with the ability to develop the complete correlative picture of organelles and cells. The instrument will also provide a much needed resource for researchers across disciplines such as physics, chemistry, biology, geology and engineering.Read moreRead less
Biodegradable magnesium alloy scaffolds for bone tissue engineering. This project aims to develop a class of porous, biocompatible, biofunctional and biodegradable magnesium alloy scaffolds with designed pore architecture and mechanical properties mimicking those of natural bone for tissue engineering applications. These magnesium alloy scaffolds will be biocompatible, able to bear loads, and will be gradually replaced by natural bone. The outcomes are expected to benefit the ageing population a ....Biodegradable magnesium alloy scaffolds for bone tissue engineering. This project aims to develop a class of porous, biocompatible, biofunctional and biodegradable magnesium alloy scaffolds with designed pore architecture and mechanical properties mimicking those of natural bone for tissue engineering applications. These magnesium alloy scaffolds will be biocompatible, able to bear loads, and will be gradually replaced by natural bone. The outcomes are expected to benefit the ageing population and people with bone abnormalities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100115
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploi ....High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploit interfacial phenomena and to tailor processing-microstructure-composition correlations, so as to design new materials with the best performance possible. Probes with unique capabilities will measure surface morphology, optical properties, elemental composition and crystallographic phase.The facility will be the first in Australia to offer a comprehensive study of structure and properties at high temperature.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775592
Funder
Australian Research Council
Funding Amount
$388,000.00
Summary
A High Resolution Analytical Scanning Electron Microscope for South-East Queensland. Scanning electron microscopy is the major visualization tool for a diverse range of research disciplines. This new generation of instrument will be able to image features close to atomic resolution and obtain quantitative analytical information from regions only a few atoms across. Because of the nature of the way the electron beam is produced, the new instrument will be able to examine particularly sensitive ma ....A High Resolution Analytical Scanning Electron Microscope for South-East Queensland. Scanning electron microscopy is the major visualization tool for a diverse range of research disciplines. This new generation of instrument will be able to image features close to atomic resolution and obtain quantitative analytical information from regions only a few atoms across. Because of the nature of the way the electron beam is produced, the new instrument will be able to examine particularly sensitive materials, such as soft bio-materials, without any loss in resolving power. This machine will be unique in Australia and be available to researchers from diverse fields of study working towards building and transforming Australian Industries and underpinning scientific discovery in nanotechnology, materials science and bioengineering.Read moreRead less
Soft materials containing hierarchy via 3D sacrificial micro-moulding. The project seeks to develop sophisticated new polymeric materials and devices not possible using current manufacturing techniques. Biomaterials based on hydrogels are ideal substrates for synthetic extra-cellular matrices due to their high water content. However, one of the challenges hindering the use of hydrogels is reproducing the transport properties found in natural tissue with hierarchical features such as vascularisat ....Soft materials containing hierarchy via 3D sacrificial micro-moulding. The project seeks to develop sophisticated new polymeric materials and devices not possible using current manufacturing techniques. Biomaterials based on hydrogels are ideal substrates for synthetic extra-cellular matrices due to their high water content. However, one of the challenges hindering the use of hydrogels is reproducing the transport properties found in natural tissue with hierarchical features such as vascularisation. To address this, the project plans to develop a 3D moulding process for generating soft materials containing precise channels decorated with defined molecules. Intended outcomes include a fundamental understanding of the 3D moulding process, and new polymers and advanced tools for bioengineers for future applications such as tissue transplants, cell guides for treating spinal cord injuries, soft robotics and microfluidic devices to study cancer metastasis. Read moreRead less
Novel manufacturing methods for tissue engineering scaffolds. Novel methods of manufacturing biodegradable polymer scaffolds around which new tissue can be grown within the human body will be developed. Surfactant - polymer assemblies will be used to produce highly porous scaffolds of tunable pore size and connectivity, shape and strength. The results will create a new avenue for systematic investigations into the effects of scaffold structure on tissue growth. This research will lead to the dev ....Novel manufacturing methods for tissue engineering scaffolds. Novel methods of manufacturing biodegradable polymer scaffolds around which new tissue can be grown within the human body will be developed. Surfactant - polymer assemblies will be used to produce highly porous scaffolds of tunable pore size and connectivity, shape and strength. The results will create a new avenue for systematic investigations into the effects of scaffold structure on tissue growth. This research will lead to the development of reliable, well-controlled manufacturing techniques for tissue engineering scaffolds, revolutionising current scaffold manufacturing practices. It will enhance existing collaborations between the University of Melbourne and the Bernard O'Brien Institute of Microsurgery.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561247
Funder
Australian Research Council
Funding Amount
$168,810.00
Summary
An advanced scanning probe microscopy facility. The development of advanced materials with high performance and functionality for applications such as medical implants, solar energy, drug delivery and gas separation is facilitated by the availability of sophisticated characterisation methods. Scanning probe microscopy (SPM) has become an essential tool in materials science, biomaterials development, nanotechnology and biology. The aim of this proposal is to provide a high performance SPM system ....An advanced scanning probe microscopy facility. The development of advanced materials with high performance and functionality for applications such as medical implants, solar energy, drug delivery and gas separation is facilitated by the availability of sophisticated characterisation methods. Scanning probe microscopy (SPM) has become an essential tool in materials science, biomaterials development, nanotechnology and biology. The aim of this proposal is to provide a high performance SPM system as an enabling technology to advance the excellent research being performed at the collaborating universities.Read moreRead less