Polyaniline Nanofibre Systems. Advanced materials such as the conducting polymer and applications of these materials at the nanoscale and up is clearly a cutting edge area of international interest. Development of readily processable nano systems has been a challenge with a clear scientific and commercial benefit. This proposal will bring linkages to Australia with the world leader in the field, Professor Kaner -UCLA, on the synthesis of polyaniline nanofibres and associated photowelding process ....Polyaniline Nanofibre Systems. Advanced materials such as the conducting polymer and applications of these materials at the nanoscale and up is clearly a cutting edge area of international interest. Development of readily processable nano systems has been a challenge with a clear scientific and commercial benefit. This proposal will bring linkages to Australia with the world leader in the field, Professor Kaner -UCLA, on the synthesis of polyaniline nanofibres and associated photowelding processes. The opportunities to Australia and the USA will be to expand the potential utility of such systems, which without such interactions would permit others to take a stake hold in this emergent and potentially lucrative technology.Read moreRead less
New Polymers for Cellulose-based Bioplastics. We will design new cellulose derivatives by combining carefully engineered synthetic polymers to cellulose. We will explore the fundamental science underpinning the manufacture of these bioplastics, and apply the concept to the design of two new materials, with (super)hydrophobic and antibacterial properties. These materials have the potential to replace synthetic plastics, which comprise one of the major outputs of the chemical industry worldwide. P ....New Polymers for Cellulose-based Bioplastics. We will design new cellulose derivatives by combining carefully engineered synthetic polymers to cellulose. We will explore the fundamental science underpinning the manufacture of these bioplastics, and apply the concept to the design of two new materials, with (super)hydrophobic and antibacterial properties. These materials have the potential to replace synthetic plastics, which comprise one of the major outputs of the chemical industry worldwide. Plastic is present everywhere in human life, but its manufacture and disposal have a strong negative impact on the environment; the new materials manufactured in this project are viable alternatives to plastics, and are sustainable from a production and disposal point of view.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453771
Funder
Australian Research Council
Funding Amount
$148,246.00
Summary
Electrochemical Electron Spin Resonance Spectrometer. Electron Spin Resonance Spectroscopy (ESR), is a technique used to determine the presence of free unpaired electrons in a sample. Detection and life time studies of radical species is critical to understanding the mechanisms involved in chemical reaction, sample degradation, performance upon exposure to light and oxidation or reduction processes. Combining ESR with an electrochemical interface permits in-situ studies on how electrons are inje ....Electrochemical Electron Spin Resonance Spectrometer. Electron Spin Resonance Spectroscopy (ESR), is a technique used to determine the presence of free unpaired electrons in a sample. Detection and life time studies of radical species is critical to understanding the mechanisms involved in chemical reaction, sample degradation, performance upon exposure to light and oxidation or reduction processes. Combining ESR with an electrochemical interface permits in-situ studies on how electrons are injected or removed from a sample, providing fundamental information on the processes occurring within the sample. Applications will be in the area of electrofunctional materials, complex biomolecular reactions, organic photovoltaics and new materials for nerve cell regeneration.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453637
Funder
Australian Research Council
Funding Amount
$256,804.00
Summary
Multi-dimensional polymer characterization facility. The microstructure of polymers dominates their physical properties. This integrated facility will create a world-leading means of characterizing in multiple dimensions the microstructure of complex polymers, eg copolymers and branched polymers. The facility will yield information on the distributions of chain end-groups, monomer microstructure, and branches, as functions of molecular weight. The facility will provide otherwise unobtainable dat ....Multi-dimensional polymer characterization facility. The microstructure of polymers dominates their physical properties. This integrated facility will create a world-leading means of characterizing in multiple dimensions the microstructure of complex polymers, eg copolymers and branched polymers. The facility will yield information on the distributions of chain end-groups, monomer microstructure, and branches, as functions of molecular weight. The facility will provide otherwise unobtainable data for a set of projects exploring questions ranging from how new synthetic materials with tailor-made properties can be created, through to how our understanding of natural polymers can be advanced to improve crop utilization.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100096
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
A unique soft matter high-performance scanning probe microscopy (HP-SPM) facility. Soft matter research touches every aspect of our lives as it covers materials from the range of plastics found in cars, television sets and other mass-manufactured products, to new medical materials for tissue engineering and sensors. The proposed facility will enable Australia's leading scientists in this area to understand better how soft matter, including both biological and new advanced soft materials, behave ....A unique soft matter high-performance scanning probe microscopy (HP-SPM) facility. Soft matter research touches every aspect of our lives as it covers materials from the range of plastics found in cars, television sets and other mass-manufactured products, to new medical materials for tissue engineering and sensors. The proposed facility will enable Australia's leading scientists in this area to understand better how soft matter, including both biological and new advanced soft materials, behaves on the nano-scale level. This will put Australian researchers and engineers in a leading position for developing new treatments against cancer and other diseases, as well as harnessing the power of biology for application in areas such as waste treatment and energy production.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100142
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
An integrated liquid chromatography mass spectrometry nuclear magnetic resonance (LC-MS-NMR) facility for applications in proteomics and organic chemistry. This application completes the requested liquid chromatography mass spectrometry nuclear magnetic resonance (LCMS-NMR) facility and will allow the training of over 150 researchers, significantly enhancing their research productivity and translation of outcomes in areas of national importance. New breakthroughs in drug development, smart mate ....An integrated liquid chromatography mass spectrometry nuclear magnetic resonance (LC-MS-NMR) facility for applications in proteomics and organic chemistry. This application completes the requested liquid chromatography mass spectrometry nuclear magnetic resonance (LCMS-NMR) facility and will allow the training of over 150 researchers, significantly enhancing their research productivity and translation of outcomes in areas of national importance. New breakthroughs in drug development, smart materials, organic electronic materials and biomedical research require routine access to cutting edge technology. The LCMS-NMR augments the capabilities of our research teams at the forefront of these efforts. These include understanding the impact of the environment on plant and animal development, pest animal control, development of new biotechnology tools, new drugs and new methods for the detection of narcotics and explosives.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668374
Funder
Australian Research Council
Funding Amount
$470,000.00
Summary
State-of-the-art NMR Facilities. This proposal will significantly enhance the NMR research capability and capacities at UoW and ANU. These schools have internationally recognised strengths in fundamentals of synthetic organic chemistry, therapeutic drug design and synthesis, protein chemistry and structural biology. This equipment will enhance the productivity of these researchers, increase their collaborative and scientific outputs and allow for training of students in the latest technologies ....State-of-the-art NMR Facilities. This proposal will significantly enhance the NMR research capability and capacities at UoW and ANU. These schools have internationally recognised strengths in fundamentals of synthetic organic chemistry, therapeutic drug design and synthesis, protein chemistry and structural biology. This equipment will enhance the productivity of these researchers, increase their collaborative and scientific outputs and allow for training of students in the latest technologies and importantly, contribute to Australia's development as a knowledge-based economy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346892
Funder
Australian Research Council
Funding Amount
$689,000.00
Summary
Protein Over-Expression/Purification and Macromolecular Structure Determination by X-Ray Diffraction. This proposal seeks funds for state-of-the-art facilities for protein over-expression and macromolecular X-ray diffraction. This will build upon recent initiatives within the collaborating institutions in the field of Structural Biology. It will enable research groups in Perth to pursue the large-scale production of important proteins and to conduct high-resolution structural studies using X-ray ....Protein Over-Expression/Purification and Macromolecular Structure Determination by X-Ray Diffraction. This proposal seeks funds for state-of-the-art facilities for protein over-expression and macromolecular X-ray diffraction. This will build upon recent initiatives within the collaborating institutions in the field of Structural Biology. It will enable research groups in Perth to pursue the large-scale production of important proteins and to conduct high-resolution structural studies using X-ray crystallographic techniques. This technology, which is one of the most important tools in modern biology, provides unique insights into the chemical mechanisms of biological macromolecules and will significantly enhance a great breadth of biological research in Western Australia.Read moreRead less
Molecular Mechanisms of Biochemical Regulation: Neutron and X-ray Scattering Studies. This project will develop and use novel neutron and x-ray scattering methods to study the molecular mechanisms by which nature regulates biochemical processes. Healthy function requires cells to tightly control and coordinate a myriad of molecular activities. My research focuses on a set of interdependent molecular networks inside cells whose behavior is controlled by the so-called 'second messengers' that tr ....Molecular Mechanisms of Biochemical Regulation: Neutron and X-ray Scattering Studies. This project will develop and use novel neutron and x-ray scattering methods to study the molecular mechanisms by which nature regulates biochemical processes. Healthy function requires cells to tightly control and coordinate a myriad of molecular activities. My research focuses on a set of interdependent molecular networks inside cells whose behavior is controlled by the so-called 'second messengers' that translate external signals into the right cellular responses. The proposed experiments will provide a unique structural framework by which we can understand how these signals are transmitted. Such knowledge is an important foundation for advances in biomedical research and biotechnology applications.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0237664
Funder
Australian Research Council
Funding Amount
$900,000.00
Summary
High Resolution Mass Spectrometer for (MS)n Chemical Characterisation. A Fourier transform ion cyclotron resonance ("FT-ICR") mass spectrometer equipped with electrospray ionisation (ESI) plus a "benchtop" matrix assisted laser desorption ionisation time of flight (MALDI-TOF) mass spectrometer are required to support the research of ca 28 research groups, including 44 postdoctoral fellows, and 138 honours and postgraduate students. By means of its high resolution and (MS)n capabilities, the FT- ....High Resolution Mass Spectrometer for (MS)n Chemical Characterisation. A Fourier transform ion cyclotron resonance ("FT-ICR") mass spectrometer equipped with electrospray ionisation (ESI) plus a "benchtop" matrix assisted laser desorption ionisation time of flight (MALDI-TOF) mass spectrometer are required to support the research of ca 28 research groups, including 44 postdoctoral fellows, and 138 honours and postgraduate students. By means of its high resolution and (MS)n capabilities, the FT-ICR-MS will provide key structural information on a wide range of synthetic and natural chemical substances, including sequence (e.g. peptides) and fragmentation patterns, while the MALDI-TOF instrument will be used primarily for high through-put proteomic analyses.Read moreRead less