Three-dimensional structures, substrate specificities and catalytic mechanisms of polysaccharide synthases. Plant wall polysaccharides are extensively used for food and fibre, and are important dietary components in human nutrition. A precise knowledge of mechanisms used by plants to synthesize these polysaccharides is unavailable, but would reveal potential routes to manipulate their biosynthesis in important crop species. For example, the levels or structures of polysaccharides might be modif ....Three-dimensional structures, substrate specificities and catalytic mechanisms of polysaccharide synthases. Plant wall polysaccharides are extensively used for food and fibre, and are important dietary components in human nutrition. A precise knowledge of mechanisms used by plants to synthesize these polysaccharides is unavailable, but would reveal potential routes to manipulate their biosynthesis in important crop species. For example, the levels or structures of polysaccharides might be modified to improve their efficacy as anti-cancer agents in human diets, to enhance digestibility of animal stock feeds, or to synthesise pharmologically valuable compounds. Thus, economic, social and environmental benefits will flow to both producers and consumers. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453524
Funder
Australian Research Council
Funding Amount
$321,456.00
Summary
The Centre for Advanced Light Microscopy: Equipment for in-vivo multiphoton microscopy and high-throughput confocal microscopy. The Centre for Advanced Light Microscopy was established with ARC RIEF funding and is currently experiencing overwhelming demand as the sole confocal provider for 260 researchers at multiple institutions in south-east Queensland. The present joint application of the Universities of Queensland and Southern Queensland seeks to build on the resounding success of the origi ....The Centre for Advanced Light Microscopy: Equipment for in-vivo multiphoton microscopy and high-throughput confocal microscopy. The Centre for Advanced Light Microscopy was established with ARC RIEF funding and is currently experiencing overwhelming demand as the sole confocal provider for 260 researchers at multiple institutions in south-east Queensland. The present joint application of the Universities of Queensland and Southern Queensland seeks to build on the resounding success of the original initiative by introducing state-of-the-art confocal and multiphoton applications. This powerful platform technology will allow structural and functional information to be obtained from sensitive live samples with unprecedented spatial and temporal resolution, augmenting and accelerating vital research in the biosciences.
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