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Early life overfeeding - mechanisms for programming obesity and long-term immune dysfunction. Early life overfeeding can lead to obesity and related changes in adulthood. With this study we will discover how overfeeding can permanently alter an animal's development so that its body weight and immune functions are dysregulated. The outcomes will facilitate appropriate design of animal experiments considering the impact of neonatal programming. They will also contribute to more efficient feeding p ....Early life overfeeding - mechanisms for programming obesity and long-term immune dysfunction. Early life overfeeding can lead to obesity and related changes in adulthood. With this study we will discover how overfeeding can permanently alter an animal's development so that its body weight and immune functions are dysregulated. The outcomes will facilitate appropriate design of animal experiments considering the impact of neonatal programming. They will also contribute to more efficient feeding protocols for meat production in agriculture and identify targets for risk management and for preventing and ameliorating early life overfeeding effects in humans. This investigation therefore has clear benefits to the social, economic, and health aspects of obesity and to basic science and agriculture.Read moreRead less
Early Nutrition and the Programming of Body Composition in Cattle. Australia is the worlds largest beef exporter with the net value of beef export valued at $4.6 billion. The economy of rural and regional Australia relies upon cattle production with the industry bringing a total value to these communities of $7.4 billion. Cattle production in remote Australia is becoming less viable as input costs of production increase relative to income earned and the beef industry is keen to transform produc ....Early Nutrition and the Programming of Body Composition in Cattle. Australia is the worlds largest beef exporter with the net value of beef export valued at $4.6 billion. The economy of rural and regional Australia relies upon cattle production with the industry bringing a total value to these communities of $7.4 billion. Cattle production in remote Australia is becoming less viable as input costs of production increase relative to income earned and the beef industry is keen to transform production methods. Protein is the major limiting nutrient in the Australian rangelands and this proposal will provide new information on how providing protein to cattle during critical periods in their pregnancy can 'program' the body composition of the growing calf to be optimal for the market.Read moreRead less