Mechanisms Of Premature Cranial Fusion: Role Of Retinol Binding Protein 4 In Osteogenesis And Suture Fusion
Funder
National Health and Medical Research Council
Funding Amount
$555,855.00
Summary
Craniosynostosis is a condition where the skull bones fuse prematurely, affecting skull shape, vision and cognition. It occurs in 1 in 2,500 births. The only treatment is surgery, which is life-threatening, costly and may need to be repeated. By studying how fusion happens in this project we may be able to devise therapies to minimize the risks and need for re-operation. Here, we hope to show that modification of a single substance in the skull of mouse models can prevent premature bone fusion.
Deciphering The Transcriptional Program That Instructs Lymphatic Endothelial Cell Fate.
Funder
National Health and Medical Research Council
Funding Amount
$541,950.00
Summary
Lymphatic vessels are essential to maintain fluid balance in most tissues of the human body. Further the lymphatic vasculature plays a central role during cancer and contributes to tumour metastasis. Despite this integral function in health and disease little is known about the molecular programs that coordinate gene expression to build a functional vasculature. This research project will address this gap in our knowledge and will open up new therapeutic avenues for lymphatic vascular disorders
Development Of Diagnostic Tools To Characterise Predictors Of Therapeutic Outcome In Severe Constipation
Funder
National Health and Medical Research Council
Funding Amount
$433,999.00
Summary
This project will use fibre-optic technology to create detailed high resolution maps of colonic motor patterns in both health and in patients with severe constipation. The data will be used in combination with actual patient symptoms to help identify specific markers of disease that can differentiate sub-types of constipation and ultimately guide and improve treatment in constipated patients
Transmission beyond linear capacity in fibre optics. This project aims to develop the concept and demonstrate the practicality of a new fibre optic communication technology that allows data transmission rates beyond currently accepted fundamental limits. This project aims to design and demonstrate the feasibility and practicality of utilising nonlinear modes of data transmission. This would assist in the management of fibre impairments that fundamentally limit further increase in data rate causi ....Transmission beyond linear capacity in fibre optics. This project aims to develop the concept and demonstrate the practicality of a new fibre optic communication technology that allows data transmission rates beyond currently accepted fundamental limits. This project aims to design and demonstrate the feasibility and practicality of utilising nonlinear modes of data transmission. This would assist in the management of fibre impairments that fundamentally limit further increase in data rate causing the capacity crunch problem. This is expected to present Australia with leading edge technology to compete in the area of high-speed, high-capacity communication, which is the backbone of our economy, heath, education, social participation, and security.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100752
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Fully-integrated fibre-based platform for a quantum information network. This project aims to combine Australia’s pioneering work developing specialised atom-filled optical fibres with world-leading quantum information storage protocols to probe the extreme limits of atom-light interactions. This will enable the creation of a compact, robust and modular node to efficiently store and process packets of optical quantum information. The node will integrate directly with current communications infra ....Fully-integrated fibre-based platform for a quantum information network. This project aims to combine Australia’s pioneering work developing specialised atom-filled optical fibres with world-leading quantum information storage protocols to probe the extreme limits of atom-light interactions. This will enable the creation of a compact, robust and modular node to efficiently store and process packets of optical quantum information. The node will integrate directly with current communications infrastructure, enabling the creation of a quantum Internet - the vital missing ingredient needed to overcome experimental hurdles that limit quantum technologies. This project is expected to enable the rapid uptake of quantum technology, boosting Australia’s capacity in this burgeoning field.Read moreRead less
Low-energy electro-photonics: novel materials, devices and systems. This project aims to develop low-power technologies for programming and tuning photonic integrated circuits (PICs). By replacing thermal tuning, the project will reduce power consumption from watts to milliwatts, which also eliminates the thermal crosstalk that limits the complexity of today's PICs. The expected outcome will be the basis for a generic field-programmable photonic chip, which can be used to rapidly prototype desig ....Low-energy electro-photonics: novel materials, devices and systems. This project aims to develop low-power technologies for programming and tuning photonic integrated circuits (PICs). By replacing thermal tuning, the project will reduce power consumption from watts to milliwatts, which also eliminates the thermal crosstalk that limits the complexity of today's PICs. The expected outcome will be the basis for a generic field-programmable photonic chip, which can be used to rapidly prototype designs for production as full custom chips as part of a new Australian industry capability. The expected benefits will be a faster innovation cycle, greater adoption of photonic technologies, and support of research into, for example, neuromorphic optical processing, and advanced communications and sensing systems.Read moreRead less
Intelligent and objective measurement of wool fibre diameter. More than a half million tones of wool produced in Australia per year are visually evaluated by human woolclassers. This fibre-classing process is subjective and heavily dependent on the experience of the classers. In this project, we will objectively measure wool fibre diameter by extracting features used by human woolclassers and by combining image processing and artificial intelligence. The fractal dimension calculated by fracta ....Intelligent and objective measurement of wool fibre diameter. More than a half million tones of wool produced in Australia per year are visually evaluated by human woolclassers. This fibre-classing process is subjective and heavily dependent on the experience of the classers. In this project, we will objectively measure wool fibre diameter by extracting features used by human woolclassers and by combining image processing and artificial intelligence. The fractal dimension calculated by fractal based texture analysis will be correlated to fibre diameter. This approach will provide an insight into an on farm and/or in shed objective measurement of wool fibre diameter.Read moreRead less
Creating a national time and frequency network for Australia. This project will develop the means to distribute accurate time and frequency across the Australian continent via an optical fibre network. This network will meet the needs of future telecommunications, science and astronomy projects including the Australian bid for the Square Kilometre Array radio-astronomy project.