Long Noncoding RNA In Space And Time, And The Regulation Of Fear Extinction
Funder
National Health and Medical Research Council
Funding Amount
$1,012,245.00
Summary
Most of our genome is made up noncoding RNA; however, nothing is known about why a special class of noncoding RNA would be expressed in synapses, and how this affects learning and memory related to neuropsychiatric disorders. Understanding the fundamental molecular machinery underlying the formation of fear extinction memory will enable the development of new treatment approaches for anxiety-related disorders that are characterised by memory deficits.
Identifying A Modifiable Risk Factor For PTSD: Insomnia-related Disruption Of Trauma Recovery Mechanisms
Funder
National Health and Medical Research Council
Funding Amount
$1,072,993.00
Summary
About 4.6 million Australians will experience PTSD during their life. Having insomnia before or immediately after trauma exposure makes it 2.5-3 times more likely someone will develop PTSD, but no one knows why. This project will, for the first time, propose and test a reason why insomnia increases the risk of PTSD. If successful, we will identify one of the few risk factors that can actually be modified in order to reduce the likelihood of developing PTSD after a trauma.