Proteomic and Transcriptional Profiling of Cartilage. Gene expression and signalling pathways that regulate cartilage formation, and its orderly transition to bone, are poorly described. Our studies will, for the first time, combine two complementary cutting-edge approaches, protein identification by proteomic analysis, and mRNA profiling by microarray analysis, to define these pathways and develop a comprehensive catalogue of proteins and gene expression patterns during cartilage development a ....Proteomic and Transcriptional Profiling of Cartilage. Gene expression and signalling pathways that regulate cartilage formation, and its orderly transition to bone, are poorly described. Our studies will, for the first time, combine two complementary cutting-edge approaches, protein identification by proteomic analysis, and mRNA profiling by microarray analysis, to define these pathways and develop a comprehensive catalogue of proteins and gene expression patterns during cartilage development and bone formation. This information will provide insight into the regulation of cartilage differentiation, maturation and structure, and will provide a critical platform for the development of more sophisticated cartilage and bone biomaterials for improved tissue repair and regeneration.Read moreRead less
Mary Astell (1666-1731): An Historical-Intellectual Role Model for Women in Philosophy. Mary Astell was an early modern English philosopher of exceptional eloquence and skill. This project will produce the first overview of her philosophical thought, the first authoritative critical edition of her magnum opus, and the first assessment of her philosophical relevance today. These outputs have the potential to encourage women's participation in philosophy and in intellectual life more generally, ou ....Mary Astell (1666-1731): An Historical-Intellectual Role Model for Women in Philosophy. Mary Astell was an early modern English philosopher of exceptional eloquence and skill. This project will produce the first overview of her philosophical thought, the first authoritative critical edition of her magnum opus, and the first assessment of her philosophical relevance today. These outputs have the potential to encourage women's participation in philosophy and in intellectual life more generally, outcomes that would be of tremendous benefit to Australia's social and economic fabric. The project will also enhance Australia's already outstanding scholarly reputation for early modern studies and the history of women's ideas.Read moreRead less
The Criticism of Heaven and Earth. Two issues have returned with vigour to public debate: the role of religion in secular society and the relation between theology and political theory. This project provides a much needed reference work that sets the current debates within a long and rich tradition. Apart from enabling us to avoid the mistakes of the past, it also brings to the fore forgotten solutions to such issues. Further, given the central role of many of these critics in a range of discipl ....The Criticism of Heaven and Earth. Two issues have returned with vigour to public debate: the role of religion in secular society and the relation between theology and political theory. This project provides a much needed reference work that sets the current debates within a long and rich tradition. Apart from enabling us to avoid the mistakes of the past, it also brings to the fore forgotten solutions to such issues. Further, given the central role of many of these critics in a range of disciplines, the series will have repercussions across a wide range of discussions within Australia and abroad. Finally, is a further step in international leadership emanating from Australia.Read moreRead less
A model of the mind which explains the role of emotions in normal cognition and affective disorder. Depression is recognised as one of the most burdensome diseases in Australia. Though we of course make no claims, as philosophers, to cure depression our contribution is to engage philosophy productively with a vital national area of empirical research. The other area of national benefit is to consolidate Australia's developing reputation as a site for the involvement of philosophy in interdiscipl ....A model of the mind which explains the role of emotions in normal cognition and affective disorder. Depression is recognised as one of the most burdensome diseases in Australia. Though we of course make no claims, as philosophers, to cure depression our contribution is to engage philosophy productively with a vital national area of empirical research. The other area of national benefit is to consolidate Australia's developing reputation as a site for the involvement of philosophy in interdisciplinary projects which link the humanities to the sciences. Furthermore, with the project's anchoring in the humanities, there is hope that a focus on, and increased understanding of, depression will have flow-on effects in the Australian community that will help ease the stigmatisation that is still felt by many of its sufferers.Read moreRead less
The Political Thought of European Women: 1400-1800. Women's political theory has so far received scant attention in the
history of political thought. Our research aims to address this problem by providing an introduction to the major political texts written by women during the period of 1400-1800. It will result in the first book-length analysis of the political theories of early modern European women and their influence on European political practice. It will highlight the work of many unjustl ....The Political Thought of European Women: 1400-1800. Women's political theory has so far received scant attention in the
history of political thought. Our research aims to address this problem by providing an introduction to the major political texts written by women during the period of 1400-1800. It will result in the first book-length analysis of the political theories of early modern European women and their influence on European political practice. It will highlight the work of many unjustly neglected female thinkers and contribute to the understanding of European traditions of political justice and the origins of our political institutions.Read moreRead less
Dhenia: A study of regionalism, population and society in Bronze Age Cyprus. The cemetery complex at Dhenia in Cyprus was in use for 2500 years, from the beginning of the Bronze Age (2,400 BCE) to the end of the Iron Age. This project is designed to sample this extensive site to assess its changing size and structure during periods of major social transformation. Comparative studies of contemporary sites will provide the basis for monitoring and explaining local, regional and island-wide relatio ....Dhenia: A study of regionalism, population and society in Bronze Age Cyprus. The cemetery complex at Dhenia in Cyprus was in use for 2500 years, from the beginning of the Bronze Age (2,400 BCE) to the end of the Iron Age. This project is designed to sample this extensive site to assess its changing size and structure during periods of major social transformation. Comparative studies of contemporary sites will provide the basis for monitoring and explaining local, regional and island-wide relationships, viewed in a context of expanding population and increasing interaction with the wider Mediterranean world. New data and approaches will contribute significantly to Cypriot archaeology and to broader archaeological theory.Read moreRead less
Mereological Composition and Material Constitution. This project embodies a number of advances in metaphysics, which is a field of research in which Australia enjoys a considerable international reputation. Our work on material constitution will also further Australia's reputation in the philosophy of mind; some of the most celebrated 20th Century contributions in the philosophy of mind have been written by Australian philosophers.
Racial Classifications in Transnational Context: Aborigines and Islanders in Australia, Native Americans, African Americans and Afro-Brazilians. This ongoing project seeks to develop a new and more powerful scholarly paradigm for understanding race through a comparative historical study designed to identify features which are common to concepts of race as they have emerged and shifted in the different societies studied, and to distinguish these from features which are specific to particular soc ....Racial Classifications in Transnational Context: Aborigines and Islanders in Australia, Native Americans, African Americans and Afro-Brazilians. This ongoing project seeks to develop a new and more powerful scholarly paradigm for understanding race through a comparative historical study designed to identify features which are common to concepts of race as they have emerged and shifted in the different societies studied, and to distinguish these from features which are specific to particular societies and/or eras. In addition to developing and demonstrating the approach, the project will reanalyse the racialisation of the four colonised groups, each of which have figured centrally in studies of race. One monograph and at least three major journal articles will result.Read moreRead less
Probability and necessity in the physical sciences. This is a philosophical study of concepts that are vital to the conduct of science: namely, dispositional concepts such as force in physics, solubility in chemistry, biological fitness, and psychological traits. By offering a radical and novel interpretation of such concepts, this project has the potential to influence the future development of Australian science. Moreover, dispositions are crucial to understanding our distinctively human persp ....Probability and necessity in the physical sciences. This is a philosophical study of concepts that are vital to the conduct of science: namely, dispositional concepts such as force in physics, solubility in chemistry, biological fitness, and psychological traits. By offering a radical and novel interpretation of such concepts, this project has the potential to influence the future development of Australian science. Moreover, dispositions are crucial to understanding our distinctively human perspective on the world. The abilities to predict, reason, communicate meanings, and to act intentionally all involve dispositional states. This project addresses the fundamental nature of such states, and will thus be of significance to anyone who hopes to understand these distinctively human phenomena.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560679
Funder
Australian Research Council
Funding Amount
$932,870.00
Summary
Materials and Surface Characterisation Facility. Australian scientists are well positioned to be at the forefront of nanotechnology, biotechnology and advanced materials development. The proposed Facility, housing state-of-the-art equipment, will enable cutting-edge research in these areas by internationally renowned researchers at the University of Melbourne, Monash University, RMIT University, and CSIRO. Such research will facilitate the development of advanced materials for diverse applicatio ....Materials and Surface Characterisation Facility. Australian scientists are well positioned to be at the forefront of nanotechnology, biotechnology and advanced materials development. The proposed Facility, housing state-of-the-art equipment, will enable cutting-edge research in these areas by internationally renowned researchers at the University of Melbourne, Monash University, RMIT University, and CSIRO. Such research will facilitate the development of advanced materials for diverse applications including drug delivery, quantum computing, photonics and tissue engineering. The multi-user Facility will enable closer collaboration with researchers in academia and industry, and will be integral in training the next generation of Australian scientists in the nano- and biosciences.Read moreRead less