Why do only some exotics become invasive? Combining ecological and genomic approaches to address alternative hypotheses in a recent Australian weed. This project will specifically test alternative hypotheses about how weeds become invasive. As invasive weeds affect both agricultural and native ecosystems equally, research on understanding the mechanisms of weed invasion is critical. Outcomes will benefit Australia by allowing better prioritisation of management against exotic plants already i ....Why do only some exotics become invasive? Combining ecological and genomic approaches to address alternative hypotheses in a recent Australian weed. This project will specifically test alternative hypotheses about how weeds become invasive. As invasive weeds affect both agricultural and native ecosystems equally, research on understanding the mechanisms of weed invasion is critical. Outcomes will benefit Australia by allowing better prioritisation of management against exotic plants already in the country by providing predictive tools to estimate likelihood of spread. For formal Pest Risk Analysis by regulators (eg Biosecurity Australia), our project will provide genomic tools by which the potential weediness of a regulated plant can be assessed through genetic screening, and forms part of an international effort to identify 'weedy genes'. Read moreRead less
Going beyond genetics: the shape of marsupial evolution and conservation. This project aims to explain the past and protect the present biodiversity of endangered marsupial mammals such as bilbies and koalas. It will generate new knowledge using an interdisciplinary combination of 3D analysis of skull shape, reflecting a mammal’s ability to feed and sense its surrounds, with the fast-moving fields of marsupial conservation and evolutionary genetics. This will help to anticipate if, and how, chan ....Going beyond genetics: the shape of marsupial evolution and conservation. This project aims to explain the past and protect the present biodiversity of endangered marsupial mammals such as bilbies and koalas. It will generate new knowledge using an interdisciplinary combination of 3D analysis of skull shape, reflecting a mammal’s ability to feed and sense its surrounds, with the fast-moving fields of marsupial conservation and evolutionary genetics. This will help to anticipate if, and how, changing environments and declining numbers reduce these species’ ability to adapt. Benefits include better information to support improved conservation decisions and identification of genes underlying the evolution of marsupial skull diversity.Read moreRead less
Seagrass adaptation and acclimation responses to extreme climatic events. This project aims to advance our understanding of how temperate marine plants in their northern limit will respond to the effects of synergistic stressors from extreme events combined with climate change. The project will study Shark Bay, a UNESCO World Heritage site, where a semi-permanent, salinity gradient maintained by shallow seagrass banks has resulted in unique ecosystems like stromatolites to persist. Expected outc ....Seagrass adaptation and acclimation responses to extreme climatic events. This project aims to advance our understanding of how temperate marine plants in their northern limit will respond to the effects of synergistic stressors from extreme events combined with climate change. The project will study Shark Bay, a UNESCO World Heritage site, where a semi-permanent, salinity gradient maintained by shallow seagrass banks has resulted in unique ecosystems like stromatolites to persist. Expected outcomes include practical solutions for building resilience to climate change mitigation in marine ecosystems. This will benefit the broader Australian community through changing how we manage significant resources and services these systems support, such as fisheries, coastal protection.Read moreRead less
A molecular/morphological view of animal evolution based on marsupials. This project aims to provide high-accuracy methods of evolutionary inference extendable to nearly all other organisms. It aims to research the evolution of animal diversity and calibrate evolutionary timescales on a case study of marsupial mammals, and differentiate between internal and external factors that govern animals’ ability to adapt and diversify. The project will collate a large, open-source three-dimensional catalo ....A molecular/morphological view of animal evolution based on marsupials. This project aims to provide high-accuracy methods of evolutionary inference extendable to nearly all other organisms. It aims to research the evolution of animal diversity and calibrate evolutionary timescales on a case study of marsupial mammals, and differentiate between internal and external factors that govern animals’ ability to adapt and diversify. The project will collate a large, open-source three-dimensional catalogue of the evolving marsupial skeleton, which could provide a detailed and publicly accessible narrative of the evolutionary past and future adaptability of Australian marsupials. The proposed development of methods to quantify the effect of past and present biodiversity crises (e.g. environmental change) is expected to inform longer-term conservation planning.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561030
Funder
Australian Research Council
Funding Amount
$441,100.00
Summary
Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiative ....Developmental Imaging Facility. This application seeks to establish a facility to undertake expression profiling in vertebrate tissues on a genomic scale and at the highest resolution. Undertaking large scale projects of this nature requires specialised robotics and dedicated infrastructure for microscopy and tissue preparation. This facility will be the first of its type in Australia will permit researchers to perform genomic scale in situ screens, many as part of large international initiatives in developmental and cellular biology. This large-scale, high-resolution expression profiling infrastructure is required to maintain international competitiveness and will dramatically improve our gene discovery, functional assessment and understanding of vertebrate development.Read moreRead less
Special Research Initiatives - Grant ID: SR0354908
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Insect-Plant Chemical Ecology Network (IPCEN). We bring together plant molecular biology, entomology and analytical chemistry to transform three leading fields of Australian research into an advanced science with far reaching capabilities in innovative research and applied outcomes. Expertise studying the biochemical pathways that produce specific plant compounds and expertise in insect recognition and response to these chemicals will be brought together. This will lead to new research outco ....The Insect-Plant Chemical Ecology Network (IPCEN). We bring together plant molecular biology, entomology and analytical chemistry to transform three leading fields of Australian research into an advanced science with far reaching capabilities in innovative research and applied outcomes. Expertise studying the biochemical pathways that produce specific plant compounds and expertise in insect recognition and response to these chemicals will be brought together. This will lead to new research outcomes and solutions to problems in agriculture, horticulture, forestry and protection of Australia's native flora. Researchers are struggling to create these links, constrained by disciplinary boundaries and geographical isolation. Key industries and researchers already support this proposal.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347607
Funder
Australian Research Council
Funding Amount
$306,000.00
Summary
FishWorks - collaborative infrastructure for zebrafish research. Zebrafish have emerged as a powerful and cost-effective animal model for studying development, biology, and disease. FishWorks represents a large-scale co-operative initiative to develop state-of-the-art zebrafish housing, manipulation, genomics and screening infrastructure in Australia. This will both support and further enhance a core group of high quality researchers to engage in cutting-edge research in areas of acknowledged ex ....FishWorks - collaborative infrastructure for zebrafish research. Zebrafish have emerged as a powerful and cost-effective animal model for studying development, biology, and disease. FishWorks represents a large-scale co-operative initiative to develop state-of-the-art zebrafish housing, manipulation, genomics and screening infrastructure in Australia. This will both support and further enhance a core group of high quality researchers to engage in cutting-edge research in areas of acknowledged expertise as well as priority within their respective institutions. In addition, it will facilitate wide-ranging collaborative arrangements to further develop and exploit this research area.Read moreRead less
The role of the immune system in pain is emerging from recent discoveries, and may hold the key to novel pain treatments. Most people experience brief gut infections from food or contagion without long-term consequences. Many others suffer symptoms for years afterwards - probably the best example of immune-based pain. Our project investigates how immune cells communicate with sensory nerves, and how these communications change from both angles after gut infection or inflammation.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100035
Funder
Australian Research Council
Funding Amount
$1,205,137.00
Summary
Founding an Australian Critical Zone Observatory Network. This proposal founds a new network of Australian Critical Zone Observatories. The network will fill essential knowledge gaps about interactions of under- and above-ground environmental processes and their responses to disturbance and change. These interactions determine the sustainability of food, clean water, mineral resources and Australian ecosystems, and cannot be studied with existing environmental infrastructure. The 5 foundation ....Founding an Australian Critical Zone Observatory Network. This proposal founds a new network of Australian Critical Zone Observatories. The network will fill essential knowledge gaps about interactions of under- and above-ground environmental processes and their responses to disturbance and change. These interactions determine the sustainability of food, clean water, mineral resources and Australian ecosystems, and cannot be studied with existing environmental infrastructure. The 5 foundational sites will host integrated monitoring equipment to observe stocks and fluxes of carbon, water, energy and mass across the “Critical Zone” – the vertical span from plant canopies to fresh bedrock. Joining a burgeoning international movement, the network will catalyse Critical Zone science in Australia.Read moreRead less
Transient Receptor Potential Channels (TRPs) As Transducers And Targets In Primary Visceral Afferents
Funder
National Health and Medical Research Council
Funding Amount
$669,130.00
Summary
Transient receptor potential, or TRP channels, are involved in generating many of the sensations we perceive, such as heat, cold, touch and pain. Some TRP channels are specialized to signal pain from visceral organs, which we must investigate if we are to find treatments for visceral pain, which are currently lacking.