Discovery of pathways to embryogenesis in pathogenic flatworm parasites using microdissection and transcriptomic technologies. The cost to Australia of flatworm parasites to animal production and human health is substantial (hundreds of millions of dollars per year). This research will give new insights into how flatworms reproduce and equip their progeny for survival, providing impetus for new vaccine or drug therapies to be developed. As these pathogens are more significant in Australia's ne ....Discovery of pathways to embryogenesis in pathogenic flatworm parasites using microdissection and transcriptomic technologies. The cost to Australia of flatworm parasites to animal production and human health is substantial (hundreds of millions of dollars per year). This research will give new insights into how flatworms reproduce and equip their progeny for survival, providing impetus for new vaccine or drug therapies to be developed. As these pathogens are more significant in Australia's near neighbours, this project will strengthen Australia's international leadership in this field. Our study will provide, for the first time for any helminth parasite, a freely available genetic database that profiles the gene expression repertoire of individual parasite tissues, a development likely to enhance the international effort in controlling these harmful diseases.Read moreRead less
Beyond the gene: Linking herbivore behaviour to plant defense gene expression. This collaborative project investigates insect herbivore avoidance of plant defence mechanisms. Our project is novel because it integrates changes in the plant at a number of different levels and links them to insect foraging behaviour. Researchers assume that insects respond to plant defences by changing their foraging behaviour. This has not been tested directly. We use the genetically well characterised plant Arabi ....Beyond the gene: Linking herbivore behaviour to plant defense gene expression. This collaborative project investigates insect herbivore avoidance of plant defence mechanisms. Our project is novel because it integrates changes in the plant at a number of different levels and links them to insect foraging behaviour. Researchers assume that insects respond to plant defences by changing their foraging behaviour. This has not been tested directly. We use the genetically well characterised plant Arabidopsis and the world-wide pest Helicoverpa (heliothis) as a model system. Damage caused to crops by insect herbivores is a direct function of behaviour. Understanding this behaviour will lead to improved pest management and reduced economic losses.Read moreRead less
Shallow water carbonate sediment dissolution in the global carbon cycle. Carbonate sediment dissolution is a globally significant process, but poorly understood in shallow marine waters. This project will determine whether the combined effect of organic matter, ocean acidification and pore water flow in shallow water carbonate sediments increases the release of calcium and alkalinity to the ocean. This project is significant because this release has not previously been accounted for and may lead ....Shallow water carbonate sediment dissolution in the global carbon cycle. Carbonate sediment dissolution is a globally significant process, but poorly understood in shallow marine waters. This project will determine whether the combined effect of organic matter, ocean acidification and pore water flow in shallow water carbonate sediments increases the release of calcium and alkalinity to the ocean. This project is significant because this release has not previously been accounted for and may lead to an additional uptake of atmospheric carbon dioxide into the global ocean, maybe some additional buffering against ocean acidification, but unfortunately, maybe also a loss of carbonate ecosystems. The outcomes of this project will make a significant contribution to our understanding of the global carbon cycle.
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Can eco-evolutionary theories explain outcomes of microbiome coalescence . Environmental microbial communities are among the most abundant and diverse natural communities, responsible for many ecologically and economically important ecosystem functions, including primary productivity and climate regulation. This project aims to identify the biotic and abiotic factors that regulate community and functional outcomes of microbiome coalescence (the mixing of two different communities) caused by natu ....Can eco-evolutionary theories explain outcomes of microbiome coalescence . Environmental microbial communities are among the most abundant and diverse natural communities, responsible for many ecologically and economically important ecosystem functions, including primary productivity and climate regulation. This project aims to identify the biotic and abiotic factors that regulate community and functional outcomes of microbiome coalescence (the mixing of two different communities) caused by natural and anthropogenic activities. The outcomes will provide a unifying ecological framework to predict variation in microbiomes across different scales, ecosystem types and disturbances, and will generate critical knowledge for the development of effective microbiome products, a rapidly growing industryRead moreRead less
Why do only some exotics become invasive? Combining ecological and genomic approaches to address alternative hypotheses in a recent Australian weed. This project will specifically test alternative hypotheses about how weeds become invasive. As invasive weeds affect both agricultural and native ecosystems equally, research on understanding the mechanisms of weed invasion is critical. Outcomes will benefit Australia by allowing better prioritisation of management against exotic plants already i ....Why do only some exotics become invasive? Combining ecological and genomic approaches to address alternative hypotheses in a recent Australian weed. This project will specifically test alternative hypotheses about how weeds become invasive. As invasive weeds affect both agricultural and native ecosystems equally, research on understanding the mechanisms of weed invasion is critical. Outcomes will benefit Australia by allowing better prioritisation of management against exotic plants already in the country by providing predictive tools to estimate likelihood of spread. For formal Pest Risk Analysis by regulators (eg Biosecurity Australia), our project will provide genomic tools by which the potential weediness of a regulated plant can be assessed through genetic screening, and forms part of an international effort to identify 'weedy genes'. Read moreRead less
Dissolution of CaCO3 in sediments in an acidifying ocean. Dissolution of calcium carbonate (CaCO3) in sediments in the context of ocean acidification is poorly understood. This project will use in situ advective benthic chamber incubations and experimental manipulations under future ocean acidification scenarios to determine the controls on the dissolution of CaCO3 in sediments. This project is significant because changes in the dissolution of CaCO3 in sediments in an acidifying ocean are at lea ....Dissolution of CaCO3 in sediments in an acidifying ocean. Dissolution of calcium carbonate (CaCO3) in sediments in the context of ocean acidification is poorly understood. This project will use in situ advective benthic chamber incubations and experimental manipulations under future ocean acidification scenarios to determine the controls on the dissolution of CaCO3 in sediments. This project is significant because changes in the dissolution of CaCO3 in sediments in an acidifying ocean are at least as important, and potentially more important, than calcification to the future accretion and survival of carbonate ecosystems. It is expected that outcomes of this project will significantly advance our understanding of the drivers of the dissolution of CaCO3 in sediments and the functioning of globally important carbonate ecosystems.Read moreRead less
Tree-mediated methane fluxes: A new frontier in the global carbon cycle. Methane is an extremely potent greenhouse gas. Recent evidence suggests that tree-mediated fluxes may be a significant, but overlooked source of methane to the atmosphere. This project aims to quantify the magnitude and drivers of tree-mediated methane fluxes from Australia’s dominant forest types. Innovatively, we will be using a novel combination of empirical field based measurements, gas tracer experiments, microbial ana ....Tree-mediated methane fluxes: A new frontier in the global carbon cycle. Methane is an extremely potent greenhouse gas. Recent evidence suggests that tree-mediated fluxes may be a significant, but overlooked source of methane to the atmosphere. This project aims to quantify the magnitude and drivers of tree-mediated methane fluxes from Australia’s dominant forest types. Innovatively, we will be using a novel combination of empirical field based measurements, gas tracer experiments, microbial analysis and modelling methods. Expected outcomes are a mechanistic understanding of tree-mediated methane fluxes, helping to constrain regional, national and global methane budgets. The results of this study will help inform publicly funded greenhouse gas abatement strategies, ensuring a maximal return on investment.Read moreRead less
eGenomics - Next generation biomonitoring of threatened species. DNA is the molecule of life and exists everywhere in the environment as a largely untapped source of information on evolution, biodiversity, and ecosystem health. Our overriding aim is to start mining that information to benefit threatened species. Based on optimized ancient DNA methods, powerful sequencing technology, whole genome analyses, and RNA profiling, we present a novel and holistic framework for genetic biomonitoring. In ....eGenomics - Next generation biomonitoring of threatened species. DNA is the molecule of life and exists everywhere in the environment as a largely untapped source of information on evolution, biodiversity, and ecosystem health. Our overriding aim is to start mining that information to benefit threatened species. Based on optimized ancient DNA methods, powerful sequencing technology, whole genome analyses, and RNA profiling, we present a novel and holistic framework for genetic biomonitoring. In two parallel model systems we will study corals and reptiles to improve environmental detection while simultaneously obtaining information on their population health. This will foster more efficient conservation of endangered species that are of tremendous importance to our marine and terrestrial ecosystems.Read moreRead less
Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Lively reproduction: do common molecules underlie all vertebrate live birth? Most animals lay eggs, but some (most mammals, including humans and some reptiles) give birth to live young. This project will reveal the molecules underlying the evolution of live birth and fundamental processes of early pregnancy, which potentially will lead to future developments in reproductive science.