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TARGETING ROS-INDUCED DAMAGE RESCUES THE DIABETIC HEART
Funder
National Health and Medical Research Council
Funding Amount
$487,669.00
Summary
Over 1 million Australians have diabetes. Many of these patients die from cardiovascular disease. We have identified free radicals as a major cause of decreased pumping function and impaired recovery from each heartbeat in the diabetic heart. Stronger antioxidant approaches and-or activation of protective protein pathways is a more effective treatment for reversing impaired function in the diabetic heart, preventing or delaying heart failure in patients with diabetes.
In autoimmune diseases the immune system attacks the body’s own tissues. Although we know that both genetic and environmental factors contribute to the risk of disease, identifying these genes and the environmental factors involved is very difficult. Furthermore, we have almost no idea how these factors interact with each other, something we need to understand in order to predict the risk of disease and reliably identify possible therapies. These are the aims of this fellowship.
A New framework to improve human-robot interaction in financial markets. This project aims to investigate the interaction of humans with robots (automated, algorithmic traders) in financial markets. It will build a novel environment based on controlled experiments within the context of financial markets. It is expected to discover how market participants choose to engage robots, and when and why robots are disengaged. The project will also investigate how the use of robots affects price behavio ....A New framework to improve human-robot interaction in financial markets. This project aims to investigate the interaction of humans with robots (automated, algorithmic traders) in financial markets. It will build a novel environment based on controlled experiments within the context of financial markets. It is expected to discover how market participants choose to engage robots, and when and why robots are disengaged. The project will also investigate how the use of robots affects price behaviour, and efficiency of allocation. This will provide significant benefits, such as enhancing Australia’s capacity for the scientific study of financial markets and for developing financial technology using an experimental method.Read moreRead less
Current therapy for AAV has major toxicities and 30% of Patients are dead or on dialysis within 3 years. This proposal aims to study a unique form of cell death termed Neutrophil extracellular traps (NETs) that initiates and perpetuates inflammation in this disease. We will use an animal model of the disease that mirrors human disease. We will inhibit crucial molecules in NET production to attenuate disease. This will provide proof of concept evidence to promote clinical trials in patients.
Discovery Early Career Researcher Award - Grant ID: DE190100887
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Economic analysis of time constraints on decision-making in health. This project aims to determine whether and how time constraints affect decision-making. Time constraints can impair the quality of decisions in health, resulting in serious medical and financial consequences. This project will employ experimental economic methods to examine how misaligned preferences and incentives influence decision-making under time constraints. The project will offer scientific evidence and accurate measureme ....Economic analysis of time constraints on decision-making in health. This project aims to determine whether and how time constraints affect decision-making. Time constraints can impair the quality of decisions in health, resulting in serious medical and financial consequences. This project will employ experimental economic methods to examine how misaligned preferences and incentives influence decision-making under time constraints. The project will offer scientific evidence and accurate measurements, provide insights into interventions to align the preferences of doctors and patients, and to lower the overtreatment of patients in the health-care market. The project expects to benefit society and contribute to a more efficient healthcare system.Read moreRead less