Nutrition in the Gouldian finch - developing an optimal 'life-history diet'. Native Australian birds such as the budgerigar, cockatiel, cockatoo, zebra finch and Gouldian finch dominate the pet trade with tens of millions kept across the world. Currently these birds are fed inadequate diets based on a few generic seeds (of European origin). Our study will investigate the nutritional needs of the Gouldian finch and the nutritional content of native Australian seeds, ultimately designing an optima ....Nutrition in the Gouldian finch - developing an optimal 'life-history diet'. Native Australian birds such as the budgerigar, cockatiel, cockatoo, zebra finch and Gouldian finch dominate the pet trade with tens of millions kept across the world. Currently these birds are fed inadequate diets based on a few generic seeds (of European origin). Our study will investigate the nutritional needs of the Gouldian finch and the nutritional content of native Australian seeds, ultimately designing an optimal diet that will dramatically improve the health of these captive birds. We will develop a new product based on Australian plants, which are adapted to growing in even in the poorest soils and climates in Australia and which will form the basis of a new commercial crop for domestic and international markets. Read moreRead less
Genetic variation in the Cotesia flavipes complex of parasitic wasps: towards the effective biological control of stem-borer pests. This project will determine the genetic variation among world populations of the parasitic wasp Cotesia flavipes, as a prelude to the preemptive biological control of stemborer pests of sugarcane in Australia. These pests currently do not occur in Australia, but are found in crops across New Guinea and Indonesia, so that their incursion into Australia is highly lik ....Genetic variation in the Cotesia flavipes complex of parasitic wasps: towards the effective biological control of stem-borer pests. This project will determine the genetic variation among world populations of the parasitic wasp Cotesia flavipes, as a prelude to the preemptive biological control of stemborer pests of sugarcane in Australia. These pests currently do not occur in Australia, but are found in crops across New Guinea and Indonesia, so that their incursion into Australia is highly likely in the future. The results of this project will clarify the taxonomic status of C. flavipes-like species in Australia and provide the means, using molecular markers, to select host strains of this wasp suitable for the control of specific stemborer speciesRead moreRead less
Enhanced biocatalysis in organic solvents for pharmaceutical biotransformation. Enzymes such as hydrolases play an important role in biotechnology because of their extreme versatility with respect to substrate specificity and stereoselectivity. The use of lipases as catalysts for optical isomer-specific organic reactions is often limited by unacceptably low enantioselectivities. We will investigate recombinant enzymes cloned from thermophilic lipolytic bacteria for synthetic reactions in orga ....Enhanced biocatalysis in organic solvents for pharmaceutical biotransformation. Enzymes such as hydrolases play an important role in biotechnology because of their extreme versatility with respect to substrate specificity and stereoselectivity. The use of lipases as catalysts for optical isomer-specific organic reactions is often limited by unacceptably low enantioselectivities. We will investigate recombinant enzymes cloned from thermophilic lipolytic bacteria for synthetic reactions in organic solvents, especially chiral resolution of mixtures in the production of pharmaceutical intermediates. Genetic improvement of lipase enantiospecificity and regioselectivity will be achieved using in vitro evolution by recombination and screening. The outcome will be cost-effective production superior biocatalysts with specifically enhanced regiospecific, enantioselective and hydrolytic characteristics.
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In vitro evolution of more thermostable dextranases for the Australian sugar industry. Dextrans are polysaccharides that adversely affect the productivity of sugarcane mills. The Australian sugar industry currently imports dextranases to deal with this problem but they are not heat stable so the mills have run at lower temperatures than optimal. We have isolated dextranases from thermophilic microorganisms and aim to improve their performance by generating superior heat-stable dextranases using ....In vitro evolution of more thermostable dextranases for the Australian sugar industry. Dextrans are polysaccharides that adversely affect the productivity of sugarcane mills. The Australian sugar industry currently imports dextranases to deal with this problem but they are not heat stable so the mills have run at lower temperatures than optimal. We have isolated dextranases from thermophilic microorganisms and aim to improve their performance by generating superior heat-stable dextranases using in vitro evolution, creating new activity levels by random mutation and recombination. The research will be significant in providing novel enzymes for domestic use, allowing import substitution and an outcome will be the development of a product with export potential.
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Fruit fly pests in northwestern Australia: invasion, hybridisation or evolution? In northwestern Australia, recent events suggest that a new and serious fruit fly pest is now present, wher previously none existed. Due to difficulties in accurate identification, we do not know whether these new pest fruit flies are endemic fruit flies that have changed their behaviour, invasions of Queensland fruit fly, or hybrids between them. This project will use DNA microsatellites to distinguish between th ....Fruit fly pests in northwestern Australia: invasion, hybridisation or evolution? In northwestern Australia, recent events suggest that a new and serious fruit fly pest is now present, wher previously none existed. Due to difficulties in accurate identification, we do not know whether these new pest fruit flies are endemic fruit flies that have changed their behaviour, invasions of Queensland fruit fly, or hybrids between them. This project will use DNA microsatellites to distinguish between these possibilities. It will also establish whether the different species involved are actually different species, or should be regarded merely as different races. Such distinctions are important both scientifically and for export quarantine purposes.Read moreRead less
Phylogeography and host specificity of stemborer parasitoids: essential components for the pre-emptive biocontrol of sugarcane pests in Australia. Stemboring insects cause huge economic losses to the sugar industry world-wide but fortunately these pests are largely absent from Australia, in part because quarantine measures have prevented their introduction. However, given their proximity, incursion of foreign stemborers from Asia pose a serious threat to Australian sugarcane. To prepare effectiv ....Phylogeography and host specificity of stemborer parasitoids: essential components for the pre-emptive biocontrol of sugarcane pests in Australia. Stemboring insects cause huge economic losses to the sugar industry world-wide but fortunately these pests are largely absent from Australia, in part because quarantine measures have prevented their introduction. However, given their proximity, incursion of foreign stemborers from Asia pose a serious threat to Australian sugarcane. To prepare effective pest management plans that can be adopted promptly in a worst-case scenario, this study will 1) develop molecular diagnostic tools to select wasp biocontrol agents that are suitable for the control of specific foreign stemborer pests, and 2) evaluate whether any Australian native wasps have the ability to kill foreign stemborers. Read moreRead less