A Randomised Placebo-controlled Trial Of Antibiotics To Prevent Urinary Tract Infection In Children
Funder
National Health and Medical Research Council
Funding Amount
$735,000.00
Summary
This study is needed to determine whether a common clinical practice long-term antibiotic treatment for children following urinary tract infection (UTI) - is safe and effective in preventing further UTI and if so, whether all appropriate children are being treated. UTI will affect about 10% of Australian children by high school age (88,000 children per year). Because UTI may damage the kidneys, the management priority for children with UTI has been prevention of further infection. Currently this ....This study is needed to determine whether a common clinical practice long-term antibiotic treatment for children following urinary tract infection (UTI) - is safe and effective in preventing further UTI and if so, whether all appropriate children are being treated. UTI will affect about 10% of Australian children by high school age (88,000 children per year). Because UTI may damage the kidneys, the management priority for children with UTI has been prevention of further infection. Currently this means the identification of children thought to be most at risk of recurrent UTI by renal tract imaging. Those found to have reflux of urine from the bladder to the kidney (present in about 30% of those with UTI) are then placed on antibiotics fro 2-5 years. Unfortunately there has never been a properly designed trial to test whether antibiotics do really prevent UTI and if so, whether children with reflux are the appropriate and only group requiring treatment. Long term antibiotics may in fact do more harm than good because of side effects like skin, bowel and blood problems and because resistant bacteria may develop. The design of this study involves the random allocation of placebo or antibiotic (cotrimoxazole, the usual antibiotic given in this case) to about 800 children after their first symptomatic UTI. These children are treated and followed for one year to determine the rate of futher UTI in both groups. Any difference in outcome between the two groups of children will be because of the antibiotic treatment. This study may prove long-term antibiotics are ineffective and therefore should not be routinely used. In this case investigation of children to detect vesicoureteric reflux would serve little purpose and should be abandoned. Alternatively antibiotic treatment may be shown as effective treatment for preventing further UTI and in this case the study will clearly identify those children who will benefit.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240101337
Funder
Australian Research Council
Funding Amount
$433,000.00
Summary
Unpacking the policy process: alcohol policy in complex social environments. In pursuit of effective alcohol policies, experts have focused on promoting evidence-based solutions, assuming that policymakers will select policies on the basis of research evidence. However, this linear model of evidence-based policy rarely plays out when related to highly contested social issues such as alcohol use. We need new ways of thinking about influencing alcohol policy that account for and engage with the re ....Unpacking the policy process: alcohol policy in complex social environments. In pursuit of effective alcohol policies, experts have focused on promoting evidence-based solutions, assuming that policymakers will select policies on the basis of research evidence. However, this linear model of evidence-based policy rarely plays out when related to highly contested social issues such as alcohol use. We need new ways of thinking about influencing alcohol policy that account for and engage with the realities of policymaking in socially complex regions, particularly policy relating to Aboriginal and Torres Strait Islander peoples. This DECRA will address this critical gap in knowledge by generating knowledge on alcohol policy processes, with a view to informing more effective engagement in the alcohol policymaking process.Read moreRead less
Creative Tropical City: Mapping Darwin's Creative Industries. This research will improve our knowledge and understanding of the creative industries in Darwin. It will provide a strong evidence base for the development of policy options for growing the creative industries in Darwin. And it will interrogate national and international creative industry policy frameworks for their applicability to Darwin.
Integrating measures of Indigenous land management effectiveness. Land management is the fastest growing Indigenous employment sector in Australia yet methods for assessing its effectiveness are poorly developed. This project will work with Indigenous land managers and their major environmental service delivery partners to develop and agree on measures of land management effectiveness to meet multiple objectives.
Evaluation Of The Effectiveness Of Mobile Preschool For Child Health And Development In Remote Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$456,369.00
Summary
This project is a retrospective study of the effectiveness of the NT Mobile Preschool Program using assessment data for children's emergent literacy, social and emotional competencies and health status. Effectiveness will be established by comparison with achievement and health status data for children not attending preschool and those in communities with no preschool service. The study will identify and describe the key factors influencing the health and learning outcomes of the three groups.
Home internet for remote Indigenous communities. While mainstream communications policies focus on the home, programs for remote Indigenous communities rely on shared community facilities. This project will analyse the benefits and complexities of home internet in three remote Indigenous communities by examining the social, economic, cultural and technical factors influencing take-up and use.
Evaluating the impact of Indigenous preferential procurement programs. This project aims to conduct a multi-disciplinary, multi-method evaluation of the implementation and impacts of Indigenous preferential procurement programs (IPPPs) on Indigenous businesses, Indigenous communities, procurers’ operations and outcomes. Bringing together researchers in partnership with corporate and government procurers, Indigenous data custodians and the Australian Bureau of Statistics we aim to produce a signi ....Evaluating the impact of Indigenous preferential procurement programs. This project aims to conduct a multi-disciplinary, multi-method evaluation of the implementation and impacts of Indigenous preferential procurement programs (IPPPs) on Indigenous businesses, Indigenous communities, procurers’ operations and outcomes. Bringing together researchers in partnership with corporate and government procurers, Indigenous data custodians and the Australian Bureau of Statistics we aim to produce a significant national program evaluation of IPPPs and the impact at the community level. The project aims to highlight ways in which IPPPs can be [re]designed to reduce implementation friction, facilitate access and participation among Indigenous businesses and help guarantee positive effects on Indigenous communities.Read moreRead less
Analysis of legislation and policies affecting the development of Indigenous wildlife-based enterprises. Entrepreneurial enterprise development by Indigenous people in remote regions is being encouraged as part of government policy to move people off welfare and into work. Indigenous knowledge of wildlife makes it a logical source of wealth generation but a range of legal and policy constraints add to substantial existing social and logistical problems. An understanding of the legal processes in ....Analysis of legislation and policies affecting the development of Indigenous wildlife-based enterprises. Entrepreneurial enterprise development by Indigenous people in remote regions is being encouraged as part of government policy to move people off welfare and into work. Indigenous knowledge of wildlife makes it a logical source of wealth generation but a range of legal and policy constraints add to substantial existing social and logistical problems. An understanding of the legal processes involved in establishing and maintaining sustainable and ongoing wildlife-based enterprises will improve their chances of success, and will also offer the opportunity to change regulatory frameworks to ensure consistency, remove contradictions and encourage workforce participation. The research will have national and international implications.Read moreRead less
Special Research Initiatives - Grant ID: SR200200677
Funder
Australian Research Council
Funding Amount
$180,000.00
Summary
Staying on Country: Infrastructure Needs for Remote Community Viability. This project introduces the concept of infrastructural biographies to revisit the history of remote community formations from the self-determination era to today. Using ethnographic approaches to understand infrastructural legacies, it aims to interrogate the governance and hardware requirements for supporting Indigenous residents to stay on country. The project will produce four case studies capturing community resilience ....Staying on Country: Infrastructure Needs for Remote Community Viability. This project introduces the concept of infrastructural biographies to revisit the history of remote community formations from the self-determination era to today. Using ethnographic approaches to understand infrastructural legacies, it aims to interrogate the governance and hardware requirements for supporting Indigenous residents to stay on country. The project will produce four case studies capturing community resilience efforts in northern and central Australia. Expected benefits include an enhanced understanding of infrastructural issues in relation to viability concerns, and improved policy strategies for Indigenous corporations, NGOs, and governments working on remote Indigenous governance, maintenance programs, and climate-readiness.Read moreRead less
Reducing young women’s offending through improved service delivery . Young women’s contact with justice and welfare agencies has increased rapidly across Australia and the world, creating a crisis that is costly and harmful, especially for young Indigenous women. Pathways into these systems are gendered; but the systems were designed to address the needs of young male offenders. This project therefore aims to discover how these systems could be better designed to improve outcomes for young women ....Reducing young women’s offending through improved service delivery . Young women’s contact with justice and welfare agencies has increased rapidly across Australia and the world, creating a crisis that is costly and harmful, especially for young Indigenous women. Pathways into these systems are gendered; but the systems were designed to address the needs of young male offenders. This project therefore aims to discover how these systems could be better designed to improve outcomes for young women. The project uses a novel approach that gives young women a voice in how five Anglicare end-users (the research partners) and other end-users can enhance their service provision in the welfare and justice sectors and become models of best practice.Read moreRead less